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SCO6570 SCO6570 SCO2285 SCO2285 SCO6984 SCO6984 SCO0263 SCO0263 SCO6988 SCO6988 mmyG mmyG SCO7685 SCO7685 SCO7254 SCO7254 SCO0276 SCO0276 SCO0387 SCO0387 SCO0529 SCO0529 SCO0714 SCO0714 SCO1885 SCO1885 SCO1337 SCO1337 SCO1049 SCO1049 SCO0735 SCO0735 SCO2752 SCO2752 SCO2847 SCO2847 SCO6255 SCO6255
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO6570SC3F9.05, possible oxidoreductase, len: 430 aa; similar to e.g. Zymomonas mobilisTR:P75002 (EMBL:Z80356) glucose-fructose oxidoreductase (433 aa), fasta scores; opt: 310 z-score: 305.5 E(): 8.4e-10, 27.2% identity in 426 aa overlap. (430 aa)
SCO2285SCC75A.31, possible oxidoreductase, len: 351 aa. Similar to many Eukaryotic dimeric dihydrodiol dehydrogenases e.g. Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) TR:BAA83489(EMBL:AB021932) dimeric dihydrodiol dehydrogenase (EC 1.3.1.20) (334 aa), fasta scores opt: 741 z-score: 868.2 E():0 39.1% identity in 335 aa overlap. Also similar to Prokaryotic oxidoreductases e.g. Streptomyces antibioticus TR:AAD55450(EMBL:AF055579) putative 3-ketoreductase (328 aa), fasta scores opt: 434 z-score: 510.8 E(): 4.5e-21 34.0% identity in 300 aa overlap. Contains a Pfam match to entry [...] (351 aa)
SCO6984Putative oxidoreductase; SC8F11.10c, possible oxidoreductase, len: 358 aa. Similar to many including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 715 z-score: 789.8 E(): 0 39.6% identity in 338 aa overlap and Streptomyces coelicolor TR:CAB60174(EMBL:AL132824) putative dehydrogenase, SCAH10.20C (337 aa), fasta scores opt: 1068 z-score: 1176.0 E(): 0 50.8% identity in 333 aa overlap. Note codon 25 offers an alternative translational start site. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (358 aa)
SCO0263SCF1.05c, possible oxidoreductase, len: 371 aa; weakly similar to many e.g. TR:O69945 (EMBL:AL023862) putative oxidoreductase from Streptomyces coelicolor (430 aa) fasta scores; opt: 224, z-score: 247.7, E(): 2e-06, (26.0% identity in 392 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (371 aa)
SCO6988Putative oxidoreductase; SC8F11.14c, possible oxidoreductase, len: 387 aa. Similar to several including: Sinorhizobium meliloti TR:O68965(EMBL:) myo-inositol dehydrogenase (EC 1.1.1.18) IdhA (330 aa), fasta scores opt: 287 z-score: 332.8 E(): 4.2e-11 30.1% identity in 356 aa overlap and Streptomyces coelicolor TR:O69945(EMBL:AL023862) putative oxidoreductase, SC3F9.05 (430 aa), fasta scores opt: 721 z-score: 825.3 E():0 34.6% identity in 390 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (387 aa)
mmyGSCP1.239c, mmyG, possible oxidoreductase, len: 393aa; previously sequenced and annotated as TR:Q9JN86 (EMBL:AJ276673). Similar to many eg. TR:Q9RK99 (EMBL:AL117322) putative oxidoreductase from Streptomyces coelicolor (371 aa) fasta scores; opt: 675, z-score: 754.9, E(): 0, 36.4% identity in 357 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (393 aa)
SCO7685SC4C2.20, conserved hypothetical protein, len: 677 aa; similar to TR:Q9Z602 (EMBL:AF116557) Pseudomonas aeruginosa protein necessary for the formation of the siderophore pyochelin PchG, 349 aa; fasta scores: opt: 559 z-score: 589.4 E(): 2.7e-25; 36.6% identity in 350 aa overlap and to Streptomyces coelicolor hypothetical protein SC4C2.23, 242 aa; fasta scores: opt: 705 z-score: 579.4 E(): 1.3e-26; 50.2% identity in 243 aa overlap. (677 aa)
SCO7254Putative myo-inositol dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (342 aa)
SCO0276SCF85.04, possible oxidoreductase, len: 417 aa. Weakly similar to many including: Bacillus subtilis TR:O34371 (EMBL:AF008220) YteT (428 aa), fasta scores opt: 296 z-score: 340.2 E(): 1.3e-11 25.3% identity in 379 aa overlap and Alcaligenes sp. (strain BR60) SW:CBAC_ALCSB (EMBL; U18133) 1-carboxy-3-chloro-3,4-dihydroxycyclo hexa-1,5-diene dehydrogenase (497 aa), fasta scores opt: 300 z-score: 345.3 E(): 7e-12 32.4% identity in 216 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (417 aa)
SCO0387SCF62.13. possible bi-domain oxidoreductase, len: 726 aa. The N-terminus is similar to many Zinc-binding dehydrogenases e.g. Sinorhizobium meliloti TR:O31186 (EMBL; AF031940) alcohol dehydrogenase (340 aa), fasta scores pt: 224 z-score: 241.8 E(): 4.1e-06 25.5% identity in 333 aa overlap. The C-terminus is similar to other oxidoreductases e.g. Zymomonas mobilis SW:GFO_ZYMMO (EMBL; M97379) glucose-fructose oxidoreductase precursor (EC 1.1.99.28) (439 aa), fasta scores opt: 243 z-score: 260.3 E(): 3.8e-07 26.1% identity in 272 aa overlap. Note this CDS is also weakly similar to the C-ter [...] (726 aa)
SCO0529Probable oxidoreductase (putative secreted protein); Glycosidase (By similarity). Has no alpha-N- acetylgalactosaminidase activity. (472 aa)
SCO0714SCF42.24, possible oxidoreductase, len: 295 aa. Identical to the previously sequenced Streptomyces coelicolor TR:Q9ZIW7 (EMBL:AF009336) Orf1 (fragment) (>195 aa). Also weakly similar to Sinorhizobium meliloti TR:O68965 (EMBL:AF059313) myo-inositol dehydrogenase (EC 1.1.1.18) (330 aa), fasta scores opt: 242 z-score: 275.5 E(): 5.9e-08 26.5% identity in 302 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (295 aa)
SCO1885SCI7.03c, possible oxidoreductase, len: 385 aa; similar to many proteins of undefined function eg. TR:Q45376 (EMBL:X90711) from a locus required for lipopolysaccharide biosynthesis in Bordetella pertussis (350 aa) fasta scores; opt: 232, z-score: 266.7, E(): 1.6e-07, (28.0% identity in 275 aa overlap). Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (385 aa)
SCO13372SCG61.19c, possible oxidoreductase, len: 301 aa; similar to SW:P37168 (MVIM_SALTY) virulence factor MviM from Salmonella typhimurium (307 aa) fasta scores; opt: 467, z-score: 533.5, E(): 3.1e-22, 33.9% identity in 304 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (301 aa)
SCO1049SCG20A.29c, probable secreted oxidoreductase, len: 387 aa; similar to SW:GFO_ZYMMO (EMBL:M97379) Zymomonas mobilis glucose-fructose oxidoreductase precursor (EC 1.1.99.28) Gfo, 439 aa; fasta scores: opt: 287 z-score: 318.4 E(): 2.9e-10; 26.6% identity in 350 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family and possible N-terminal region signal peptide sequence. (387 aa)
SCO07353SC5B7.13, possible oxidoreductase, len: 400 aa; low similarity to TR:Q9KDG5 (EMBL:AP001511) Bacillus halodurans NADH-dependent dehydrogenase BH1248, 340 aa; fasta scores: opt: 243 z-score: 286.8 E(): 1.9e-08; 24.8% identity in 242 aa overlap. Contains Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (400 aa)
SCO2752SCC57A.23c, possible oxidoreductase, len: 378 aa. Weakly similar to several other putative oxidoreductases e.g. Streptomyces coelicolor TR:O69945 (EMBL:AL023862) putative oxidoreductase (430 aa), fasta scores opt: 252 z-score: 300.4 E(): 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (378 aa)
SCO2847Putative oxidoreductase; SCE20.21, possible oxidoreductase, len: 360 aa. Similar to several other putative oxidoreductases e.g. Escherichia coli SW:YDGJ_ECOLI(EMBL:AE000258) hypothetical oxidoreductase (346 aa), fasta scores opt: 873 z-score: 972.9 E():0 45.0% identity in 353 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family. (360 aa)
SCO6255SCAH10.20, possible dehydrogenase, len: 337 aa; similar to SW:STRI_STRGR (EMBL:Y00459) Stretomyces griseus streptomycin resistance protein StrI, 348 aa; fasta scores: opt: 582 z-score: 670.0 E(): 6.1e-30; 39.5% identity in 344 aa overlap and to SW:MI2D_BACSU (EMBL;M76431) Bacillus subtilis myo-inositol dehydrogenase (EC 1.1.1.18) Idh or IolG OR e83G, 330 aa; fasta scores: opt: 534 z-score: 615.6 E(): 6.5e-27; 28.8% identity in 351 aa overlap. Contains match to Pfam entry PF01408 GFO_IDH_MocA, oxidoreductase family. (337 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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