(2 nodes) Permease MlaE network (Streptomyces coelicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCO2421	SCC42.02c, possible ABC-transporter integral membrane protein, len: 254 aa; similar to TR:O53546 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 26.6 kD protein MTV023.08c, 254 aa; fasta scores: opt: 881 z-score: 1004.0 E(): 0; 50.8% identity in 242 aa overlap. Contains possible hydrophobic membrane spanning regions. (254 aa)
	SCO2420	SCC42.01c, possible ABC-transporter integral membrane protein (fragment), len: >161 aa; similar to TR:O53545 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 29.6 kD protein MTV023.07c, 280 aa; fasta scores: opt: 565 z-score: 630.0 E(): 1.3e-27; 54.5% identity in 154 aa overlap. Contains possible hydrophobic membrane spanning regions; SC8A2.08c, conserved hypothetical protein (fragment), len: >139 aa; similar to TR:O53966 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 28.1 kDa protein MTV051.03, 271 aa; fasta scores: opt: 474 z-score: 595.0 E(): 1.3e-25; 48.6% identity [...] (268 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO2420	SCO2421	gene:17760019	gene:17760020	SCC42.01c, possible ABC-transporter integral membrane protein (fragment), len: >161 aa; similar to TR:O53545 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 29.6 kD protein MTV023.07c, 280 aa; fasta scores: opt: 565 z-score: 630.0 E(): 1.3e-27; 54.5% identity in 154 aa overlap. Contains possible hydrophobic membrane spanning regions; SC8A2.08c, conserved hypothetical protein (fragment), len: >139 aa; similar to TR:O53966 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 28.1 kDa protein MTV051.03, 271 aa; fasta scores: opt: 474 z-score: 595.0 E(): 1.3e-25; 48.6% identity [...]	SCC42.02c, possible ABC-transporter integral membrane protein, len: 254 aa; similar to TR:O53546 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 26.6 kD protein MTV023.08c, 254 aa; fasta scores: opt: 881 z-score: 1004.0 E(): 0; 50.8% identity in 242 aa overlap. Contains possible hydrophobic membrane spanning regions.	0.994
SCO2421	SCO2420	gene:17760020	gene:17760019	SCC42.02c, possible ABC-transporter integral membrane protein, len: 254 aa; similar to TR:O53546 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 26.6 kD protein MTV023.08c, 254 aa; fasta scores: opt: 881 z-score: 1004.0 E(): 0; 50.8% identity in 242 aa overlap. Contains possible hydrophobic membrane spanning regions.	SCC42.01c, possible ABC-transporter integral membrane protein (fragment), len: >161 aa; similar to TR:O53545 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 29.6 kD protein MTV023.07c, 280 aa; fasta scores: opt: 565 z-score: 630.0 E(): 1.3e-27; 54.5% identity in 154 aa overlap. Contains possible hydrophobic membrane spanning regions; SC8A2.08c, conserved hypothetical protein (fragment), len: >139 aa; similar to TR:O53966 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 28.1 kDa protein MTV051.03, 271 aa; fasta scores: opt: 474 z-score: 595.0 E(): 1.3e-25; 48.6% identity [...]	0.994