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SCO5820 SCO5820 SCO0159 SCO0159 SCO0194 SCO0194 SCO0414 SCO0414 SCO0600 SCO0600 SCO0632 SCO0632 SCO0803 SCO0803 SCO0864 SCO0864 SCO0866 SCO0866 SCO0895 SCO0895 SCO0942 SCO0942 SCO1263 SCO1263 SCO1276 SCO1276 SCO1564 SCO1564 SCO1723 SCO1723 SCO1876 SCO1876 SCO2465 SCO2465 SCO2639 SCO2639 SCO2742 SCO2742 SCO2954 SCO2954 SCO3068 SCO3068 SCO3202 SCO3202 SCO3323 SCO3323 SCO3356 SCO3356 SCO3450 SCO3450 SCO3613 SCO3613 SCO3626 SCO3626 SCO3709 SCO3709 SCO3736 SCO3736 SCO3892 SCO3892 SCO4005 SCO4005 SCO4034 SCO4034 SCO4035 SCO4035 SCO4117 SCO4117 SCO4146 SCO4146 SCO4409 SCO4409 SCO4452 SCO4452 SCO4757 SCO4757 SCO4864 SCO4864 SCO4866 SCO4866 SCO4895 SCO4895 SCO4908 SCO4908 SCO4938 SCO4938 SCO4996 SCO4996 SCO5147 SCO5147 SCO5216 SCO5216 SCO5243 SCO5243 SCO5621 SCO5621 SCO5934 SCO5934 SCO6239 SCO6239 SCO6520 SCO6520 SCO6996 SCO6996 SCO7105 SCO7105 SCO7112 SCO7112 SCO7144 SCO7144 SCO7192 SCO7192 SCO7278 SCO7278 SCO7314 SCO7314 SCO7341 SCO7341 SCP1.116 SCP1.116 SCP1.151c SCP1.151c
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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SCO5820Major vegetative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Its activity is stimulated by RbpA. (511 aa)
SCO0159SCJ1.08 putative ECF sigma factor, len: 322 aa, similar to many e.g. S. coelicolor TR:CAB44418 (EMBL:AL078610) putative ECF sigma factor SCH35.09 (223 aa) fasta scores, opt: 656 z-score: 777.0 E(): 0 64.6% identity in 175 aa overlap and Mycobacterium tuberculosis SIGI protein TR:O50445 (EMBL; AL010186)(290 aa), fasta scores opt: 385 z-score: 458.0 E(): 3.7e-18 30.0% identity in 290 aa overlap. Contains a Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Possible helix-turn-helix motif between 142-163 aa, score +4.11 SD. (322 aa)
SCO0194SCJ12.06, possible sigma factor, len: 202 aa. Similar to many including: Rhodobacter sphaeroide TR:O33546 (EMBL; U11283) RpoE homologue (168 aa), fasta scores opt: 291 z-score: 373.4 E(): 1.9e-13 35.4% identity in 161 aa overlap and Streptomyces coelicolor TR:O54163 (EMBL; AL021411) putative sigma factor SC7H1.04 (200 aa), fasta scores opt: 255 z-score: 327.4 E(): 7.1e-11 33.7% identity in 184 aa overlap. Contains a PS01063 Sigma-70 factors ECF subfamily signature and a Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Contains a possible helix-turn-helix motif [...] (202 aa)
SCO0414SCF51.13c, possible RNA polymerase sigma factor, len: 298 aa; similar to TR:CAB42013 (EMBL:AL049754) Streptomyces coelicolor putative RNA polymerase sigma factor SCH10.4c, 294aa; fasta scores: opt: 614 z-score: 721.0 E(): 8.7e-33; 41.4% identity in 285 aa overlap and to TR:O86856 (EMBL:AJ007313) Streptomyces coelicolor sigma factor, SigT, 236aa; fasta scores: opt: 160 z-score: 194.6 E(): 0.0018; 31.0% identity in 158 aa overlap; Belongs to the sigma-70 factor family. (298 aa)
SCO0600RNA polymerase sigma factor sig8; SCF55.24, sig8, len: 266 aa; identical to previously sequenced TR:CAB55833 (EMBL:AJ249580) Streptomyces coelicolor Sig8 protein, 266 aa and similar to SW:RPOF_STRCO (EMBL:L11648) Streptomyces coelicolor RNA polymerase sigma-F factor, SigF, 287 aa; fasta scores: opt: 759 z-score: 872.2 E(): 0; 47.6% identity in 269 aa overlap and to Streptomyces coelicolor putative RNA polymerase sigma factor SC5H1.14, 295 aa; fasta scores: opt: 1265 z-score: 1335.0 E(): 0; 73.8% identity in 263 aa overlap. Contains match to Pfam entry PF00140 sigma70, Sigma-70 factor a [...] (281 aa)
SCO0632SCF56.16, probable RNA polymerase sigma factor, len: 194 aa; similar to TR:CAB50938 (EMBL:AL096849) Streptomyces coelicolor SCI11.12c, 185 aa; fasta scores: opt: 710 z-score: 848.0 E(): 0; 62.4% identity in 173 aa overlap and to SW:SIGW_BACSU (EMBL:AB002150) Bacillus subtilis RNA polymerase sigma factor SigW, 187 aa; fasta scores: opt: 209 z-score: 258.8 E(): 4.9e-07; 24.9% identity in 181 aa overlap. Contains a possible helix-turn-helix motif at residues 159..180 (+2.77 SD); Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
SCO0803SCF43.14c, possible RNA polymerase sigma factor, len: 330 aa. Similar to Mycobacterium smegmatis TR:O05767 (EMBL:U87307) extracytoplasmic function alternative sigma factor SigE (204 aa), fasta scores opt: 234 z-score: 278.1 E(): 4.1e-08 29.1% identity in 175 aa overlap. Also highly similar to many other putative sigma factors e.g. Streptomyces coelicolor TR:Q9X8P3 (EMBL:AL049754) putative RNA polymerase sigma factor SCH10.04C (294 aa), fasta scores opt: 915 z-score: 1056.2 E():0 52.9% identity in 293 aa overlap. (324 aa)
SCO0864SCM2.17c, probable ECF-family sigma factor, len: 198 aa. Highly similar to many sigma factors including: Streptomyces coelicolor TR:O86856 (EMBL:AJ007313) sigma factor SigT (236 aa), fasta scores opt: 268 z-score: 337.2 E(): 2.1e-11 34.3% identity in 181 aa overlap and Mycobacterium tuberculosis SW:RPSC_MYCTU (EMBL:Z73966) probable RNA polymerase sigma-C factor SigC (185 aa), fasta scores opt: 517 z-score: 643.3 E(): 1.9e-28 50.8% identity in 177 aa overlap. Note this CDS appears to be a duplicated on this cosmid and shares 68.5 % identity, in 197 aa overlap, with the downstream gene, [...] (198 aa)
SCO0866SCM2.19c, probable ECF-family sigma factor, len: 213 aa. Highly similar to many sigma factors including: Streptomyces coelicolor TR:O86856 (EMBL:AJ007313) sigma factor SigT (236 aa), fasta scores opt: 292 z-score: 354.1 E(): 2.4e-12 35.7% identity in 185 aa overlap and Mycobacterium tuberculosis SW:RPSC_MYCTU(EMBL:Z73966) probable RNA polymerase sigma-C factor SigC (185 aa), fasta scores opt: 530 z-score: 636.2 E(): 4.6e-28 51.7% identity in 178 aa overlap. Note this CDS appears to be a duplicated on this cosmid and shares 68.5 % identity, in 197 aa overlap, with the upstream gene, SCM [...] (213 aa)
SCO0895RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (339 aa)
SCO0942SCM10.30, possible RNA polymerase sigma factor, len: 184 aa; similar to various sigma factors, e.g. TR:O53798 (EMBL:AL021958) Mycobacterium tuberculosis, and Mycobacterium bovis RNA polymerase sigma factor SigJ, 177 aa; fasta scores: opt: 364 z-score: 454.2 E(): 6.6e-18; 42.0% identity in 174 aa overlap, to TR:O86856 (EMBL:AJ007313) Streptomyces coelicolor sigma factor SigT, 236 aa; fasta scores: opt: 235 z-score: 295.6 E(): 4.5e-09; 35.4% identity in 161 aa overlap, to SW:RPSC_MYCTU (EMBL:Z73966) Mycobacterium tuberculosis probable RNA polymerase sigma-C factor SigC, 185 aa; fasta sco [...] (184 aa)
SCO12632SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (295 aa)
SCO12762SCG18.23, sigJ, RNA polymerase ECF sigma factor, len: 198 aa; identical to previously sequenced TR:AAF35371 (EMBL:AF225460) Streptomyces coelicolor RNA polymerase ECF sigma factor SigJ, 198 aa. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (198 aa)
SCO1564SCL11.20c, possible RNA polymerase sigma factor ECF subfamily, len: 166 aa; similar to SW:RFAY_XANCP (EMBL:U19896) Xanthomonas campestris probable RNA polymerase sigma factor RfaY, 217 aa; fasta scores: opt: 135 z-score: 168.4 E(): 0.058; 30.9% identity in 136 aa overlap. (166 aa)
SCO1723SCI11.12c, possible RNA polymerase sigma factor, len: 185 aa; weakly similar to RNA polymerase sigma factors e.g. SW:CARQ_MYXXA (EMBL:X71062), CarQ, Myxococcus xanthus RNA polymerase sigma factor (174 aa), fasta scores; opt: 233 z-score: 295.7 E(): 3.9e-09, 29.3% identity in 167 aa overlap. Similar to many putative sigma factors e.g. TR:O53730 (EMBL:AL021932), SigK, Mycobacterium tuberculosis probable RNA polymerase sigma factor (187 aa) (51.4% identity in 173 aa overlap). Similar to others from S.coelicolor e.g. TR:O54163 (EMBL:AL021411) S. coelicolor possible sigma factor (200 aa) (3 [...] (185 aa)
SCO1876SCI39.23, possible RNA polymerase sigma factor, len: 190 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma-E factor SigE, 176 aa; fasta scores: opt: 210 Z-score: 262.1 bits: 55.1 E(): 5.2e-07; 34.177% identity in 158 aa overlap. Contains possible helix-turn-helix motif at residues 132..153 (+3.59 SD); Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
SCO2465RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (396 aa)
SCO2639SC8E4A.09c, possible RNA polymerase sigma factor, len: 208 aa; similar to TR:O53798 (EMBL:AL021958) Mycobacterium tuberculosis RNA polymerase sigma factor SigJ, 177 aa; fasta scores: opt: 221 z-score: 269.6 E(): 1.3e-07; 34.9% identity in 146 aa overlap and to SW:SIGV_BACSU (EMBL:U93874) Bacillus subtilis RNA polymerase sigma factor SigV, 166 aa; fasta scores: opt: 177 z-score: 218.8 E(): 8.9e-05; 28.2% identity in 142 aa overlap. Contains possible helix-turn-helix motif at residues 171..192 (+2.79 SD); Belongs to the sigma-70 factor family. ECF subfamily. (208 aa)
SCO2742SCC57A.13c, possible sigma factor, len: 315 aa. Similar to many putative Streptomyces coelicolor ECF sigma factors e.g. TR:CAB53126 (EMBL:AL109962) SCJ1.08 (322 aa), fasta scores opt: 506 z-score: 595.6 E(): 8.7e-26 34.5% identity in 290 aa overlap. Also similar to Mycobacterium tuberculosis TR:O53378 (EMBL:AL021841) putative sigma factor (fragment)(312 aa), fasta scores opt: 525 z-score: 617.9 E(): 5e-27 33.7% identity in 291 aa overlap. Contains a putative helix-turn-helix motif situated between residues 152..173 (+2.66 SD); Belongs to the sigma-70 factor family. (315 aa)
SCO2954SCE59.13c, probable RNA polymerase sigma factor, len: 194 aa; similar to TR:CAB63191 (EMBL:AL133469) Streptomyces coelicolor putative RNA polymerase sigma factor SCM10.30, 184 aa; fasta scores: opt: 522 z-score: 641.7 E(): 2.5e-28; 54.7% identity in 161 aa overlap and to SW:SIGY_BACSU (EMBL:D83026) Bacillus subtilis RNA polymerase sigma factor SigY, 178 aa; fasta scores: opt: 211 z-score: 266.1 E(): 2.1e-07; 27.2% identity in 169 aa overlap Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) PS01063 Sigma-70 factors ECF subfamily signature. (194 aa)
SCO3068SCE25.09, sig15, putative RNA polymerase sigma factor, len: 304 aa; identical to previously sequenced TR:CAB55836 (EMBL:AJ249581) Streptomyces coelicolor A3(2) putative RNA polymerase sigma factor Sig15, 304 aa. Contains Pfam match to entry PF00140 sigma70, Sigma-70 factor and match to Prosite entry PS00715 Sigma-70 factors family signature 1. Contains also possible helix-turn-helix motif at residues 269..290 (+6.83 SD). (304 aa)
SCO3202RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (332 aa)
SCO3323SCE68.21, probable RNA polymerase sigma factor, len: 177 aa; similar to many members of the extracytoplasmic function sigma factor family e.g. SW:CARQ_MYXXA (EMBL:X71062), CarQ, Myxococcus xanthus RNA polymerase sigma factor (174 aa), fasta scores; opt: 237 z-score: 281.3 E(): 2.4e-08, 32.0% identity in 169 aa overlap. Similar to others from S. coelicolor e.g. TR:O54163 (EMBL:AL021411), SC7H1.04, possible sigma factor (200 aa) (30.8% identity in 172 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (177 aa)
SCO3356ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme. (177 aa)
SCO3450SCE46.07c, probable RNA polymerase sigma factor (ECF subfamily), len: 201 aa; similar to TR:O87834 (EMBL:AJ010320) Streptomyces coelicolor RNA polymerase sigma factor SigR, 227 aa; fasta scores: opt: 337 z-score: 413.7 E(): 1.1e-15; 34.1% identity in 208 aa overlap and to SW:RPOE_MYCTU (EMBL:Z95120) Mycobacterium tuberculosis RNA polymerase sigma-E factor (sigma-24), 216 aa; fasta socres: opt: 339 z-score: 416.4 E(): 7.5e-16; 35.4% identity in 189 aa overlap. Contains match to Pfam entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and match to PS01063 Sigma-70 factors ECF subf [...] (201 aa)
SCO3613SC66T3.24c, possible RNA polymerase sigma factor, len: 190 aa; weakly similar to many e.g. SW:RPOE_STRCO (EMBL:L29636), AigE, S.coelicolor RNA polymerase sigma-E factor (176 aa), fasta scores; opt: 236 z-score: 274.0 E(): 6.1e-08, 30.9% identity in 162 aa overlap. The start site is uncertain as there is a second possible start site at codon 7; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
SCO3626SCH10.04c, probable RNA polymerase sigma factor, len: 294 aa; similar to many e.g. TR:O05735 (EMBL:U87308) SigE, Mycobacterium avium extracytoplasmic function alternative sigma factor (251 aa), fasta scores; opt: 226 z-score: 266.2 E(): 1.6e-07, 29.8% identity in 168 aa overlap; Belongs to the sigma-70 factor family. (294 aa)
SCO3709SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family. (184 aa)
SCO3736SCH22A.14c, probable RNA polymerase ECF sigma factor, len: 163 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma-E factor SigE, 176 aa; fasta scores: opt: 214 z-score: 282.2 E(): 2.7e-08; 32.7% identity in 159 aa overlap; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
SCO3892SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13. (236 aa)
SCO40052SC10A7.09, probable RNA polymerase sigma factor, len: 157 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma-E factor SigE, 176 aa; fasta scores: opt: 451 z-score: 556.7 E(): 1.7e-23; 48.7% identity in 150 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 120..141 (+3.36 SD). (157 aa)
SCO40342SC10A7.38c, probable RNA polymerase sigma factor, len: 318 aa; highly similar to TR:Q9RIS5 (EMBL:AJ249581) Streptomyces coelicolor A3(2) Sig15 protein, 304 aa; fasta scores: opt: 1201 z-score: 1341.5 E(): 0; 66.6% identity in 287 aa overlap and to SW:RPOF_STRCO (EMBL:L11648) Streptomyces coelicolor RNA polymerase sigma-F factor SigF or RpoX, 287 aa; fasta scores: opt: 950 z-score: 1063.4 E(): 0; 58.6% identity in 261 aa overlap. Contains Pfam match to entry PF00140 sigma70, Sigma-70 factor and match to Prosite entry PS00715 Sigma-70 factors family signature 1. Also contains a possible [...] (318 aa)
SCO4035RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal spore maturation. (287 aa)
SCO4117SCD72A.03, possible membrane protein, len: 687aa; contains possible membrane-spanning hydrophobic region (358-453aa) and proline-rich region (495-540aa); Belongs to the sigma-70 factor family. ECF subfamily. (687 aa)
SCO4146SCD84.13, probable ECF subfamily sigma factor, len: 180 aa; similar to TR:Q9WWP4 (EMBL:AF121850) Synechococcus sp. SigH, 199 aa; fasta scores: opt: 273 z-score: 333.6 E(): 4e-11; 37.4% identity in 163 aa overlap and to TR:O05767 (EMBL:U87307) Mycobacterium smegmatis extracytoplasmic function alternative sigma factor, SigE, 204 aa; fasta scores: opt: 261 z-score: 319.3 E(): 2.5e-10; 33.5% identity in 188 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (180 aa)
SCO4409SC6F11.07c, possible RNA polymerase sigma factor, len: 197 aa; similar to SW:SIGZ_BACSU (EMBL:U93875) Bacillus subtilis RNA polymerase sigma factor SigZ, 176 aa; fasta scores: opt: 166 z-score: 208.5 E(): 0.00041; 27.0% identity in 148 aa overlap; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa)
SCO4452Putative RNA polymerase sigma factor; SCD6.30c, hypothetical protein, len: 383 aa; similar to TR:O86798 (EMBL:AL031317) Streptomyces coelicolor hypothetical 45.7 kD protein SC6G4.35, 419 aa; fasta scores: opt: 312 z-score: 358.2 E(): 1.7e-12; 42.3% identity in 404 aa overlap and to many putative RNA polymerase sigma facotrs, e.g. TR:Q984U6 (EMBL:AP003012) Rhizobium loti (Mesorhizobium loti) sigma-70 factor, ECF subfamily MLL7837 417 aa; fasta scores: opt: 535 Z-score: 594.4 E(): 1.8e-25; 43.325% identity in 397 aa overlap. (383 aa)
SCO4757Conserved hypothetical protein; SC6G4.35, unknown, len: 419 aa; similar to hypotheti cal protein from Rhizobium meliloti TR:Q52997 (EMBL:L39265) (66 aa, partial) opt: 154 z-score: 162.6 E(): 0.086, 40.0% identity in 50 aa overlap. N-terminus is weakly similar to several sigma factors e.g. CARQ_MYXXA RNA polymerase sigma factor carQ (174 aa), fasta scores; opt: 153 z-score: 172. 4 E(): 0.024, 29.8% identity in 161 aa overlap. (419 aa)
SCO4864SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (225 aa)
SCO4866SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (220 aa)
SCO48952SCK8.21c, possible ECF sigma factor, len: 334 aa; similar to TR:O07426 (EMBL:Z97050) Mycobacterium tuberculosis RNA polymerase sigma subunit MTCI28.22c, 370 aa; fasta scores: opt: 818 z-score: 941.2 E(): 0; 44.7% identity in 318 aa overlap and to TR:Q9K3H7 (EMBL:AL390188) Streptomyces coelicolor putative ECF-sigma factor 2SCG18.10c, 295 aa; fasta scores: opt: 219 z-score: 257.6 E(): 8.8e-07; 31.8% identity in 314 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 159..180 (+4.07 SD). (334 aa)
SCO49082SCK8.34, probable RNA polymerase sigma factor (fragment), len: 196 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma factor SigE, 176 aa; fasta scores: opt: 377 z-score: 396.4 E(): 1.7e-14; 44.6% identity in 148 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 148..169 (+3.34 SD). (196 aa)
SCO4938SCK13.30, possible ECF-sigma factor, len: 304 aa; similar to TR:Q9RJS2 (EMBL:AL132707) Streptomyces coelicolor putative RNA polymerase sigma factor SCF51.13c, 298 aa; fasta scores: opt: 1110 z-score: 1299.2 E(): 0; 58.4% identity in 296 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 144..165 (+2.59 SD). (304 aa)
SCO49962SCK36.19c, probable RNA polymerase ECF sigma factor, len: 169 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma-E factor SigE or SCE94.07, 176 aa; fasta scores: opt: 278 Z-score: 347.2 bits: 70.7 E(): 9.9e-12; 36.527% identity in 167 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (169 aa)
SCO5147SCP8.10, probable ECF-subfamily sigma factor, len: 223 aa; similar to TR:O05735 (EMBL:U87308) Mycobacterium avium extracytoplasmic function alternative sigma factor SigE, 251 aa; fasta scores: opt: 852 z-score: 1013.1 E(): 0; 62.5% identity in 216 aa overlap and to SW:CARQ_MYXXA (EMBL:X71062) Myxococcus xanthus RNA polymerase sigma factor CarQ, 174 aa; fasta scores: opt: 285 z-score: 347.6 E(): 6.8e-12; 36.5% identity in 159 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Also contains a possible helix-turn-helix motif at residues 164..185 [...] (223 aa)
SCO5216RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor (RsrA) until released. Responds to thiol-oxidative stress, involved in regulation of about 30 genes and operons, including the thioredoxin system (trxB-trxA, trxC), ribosomal protein L31, RNA polymerase-binding protein RbpA and mycothiol (MSH) biosynthetic (mshA) and recycling genes (mca). In conjunction with its cognate anti-s [...] (227 aa)
SCO52432SC7G11.05c, sig1, RNA polymerase sigma factor, len: 361 aa; identical to previously sequenced TR:Q9RIT0 (EMBL:AJ249450) Streptomyces coelicolor A3(2) Sig1 protein, 361 aa and similar TR:CAB93744 (EMBL:AL357613) Streptomyces coelicolor regulatory protein SC5F8.16c, 83 aa; fasta scores: opt: 414 z-score: 534.4 E(): 3.9e-24; 72.0% identity in 82 aa overlap. Contains Pfam match to entry PF00140 sigma70, Sigma-70 factor and possible helix-turn-helix motif at residues 326..347 (+7.10 SD). (361 aa)
SCO5621RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (280 aa)
SCO5934SC7H1.04, possible sigma factor, len: 200 aa; some similarity to sigma factors (ECF subfamily) from diverse organisms e.g. Alcaligenes eutrophus CNRH_ALCEU P37978 rna polymerase sigma factor cnrh (191 aa), fasta scores; opt: 230 z-score: 337.3 E(): 1.4e-11, 29.5% identity in 183 aa overlap; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)
SCO6239SCAH10.04c, possible sigma factor, len: 322 aa; similar to TR:CAB42013 (EMBL:AL049754) Streptomyces coelicolor putative sigma factor, SCH10.04c, 294 aa; fasta scores: opt: 379 z-score: 438.7 E(): 4.6e-17; 34.7% identity in 291 aa overlap and to (EMBL:AL132707) Streptomyces coelicolor SCF51.13c, 298 aa; fasta scores: opt: 833 z-score: 802.7 E(): 0; 44.9% identity in 305 aa overlap; Belongs to the sigma-70 factor family. (322 aa)
SCO6520SC5C7.05, probable RNA polymerase sigma factor, len: 266 aa; simlar to S. coelicolor sigma factors of the SigB subfamily e.g. TR:O52313 (EMBL:AF036131) putative RNA polymerase secondary sigma factor SigG (263 aa), fasta scores; opt: 1258 z-score: 1540.5 E(): 0, 72.9% identity in 251 aa overlap, and to RPOF_STRAU RNA polymerase sigma-F factor (297 aa), fasta scores; opt: 713 z-score: 858.3 E(): 0, 42.6% identity in 312 aa overlap. Possible alternative start 216 bp upstream, not supported by FramePlot. Contains helix-turn-helix motif at aa 228-249 (Score 2104, +6.35 SD) and Pfam match to [...] (266 aa)
SCO6996SC8F11.22, possible RNA polymerase sigma factor, len: 191 aa. Weakly similar to Streptomyces coelicolor sigma factor TR:CAB76082 (EMBL:AL157953) putative RNA polymerase sigma factor, SCL11.20C (166 aa), fasta scores opt: 206 z-score: 259.9 E(): 4.8e-07 30.4% identity in 161 aa overlap; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
SCO7105SC4B10.06c, possible RNA polymerase sigma factor, len: 301 aa; similar to TR:Q9S1V5 (EMBL:AL109950) Streptomyces coelicolor putative sigma factor SCJ24.18c, 250 aa; fasta scores: opt: 877 z-score: 1049.7 E(): 0; 54.7% identity in 236 aa overlap and to Streptomyces coelicolor St4B10.13c, 298; fasta scores: opt: 1112 z-score: 1131.2 E(): 0; 57.3% identity in 288 aa overlap. Also contains a possible helix-turn-helix motif at residues 133..154 (+3.38 SD); Belongs to the sigma-70 factor family. (301 aa)
SCO7112SC4B10.13c, probable ECF-family RNA polymerase sigma factor, len: 298 aa; similar to TR:Q9S1V5 (EMBL:AL109950) Streptomyces coelicolor putative sigma factor SCJ24.18c, 250 aa; fasta scores: opt: 1127 z-score: 1362.0 E(): 0; 72.8% identity in 243 aa overlap and to Streptomyces coelicolor SC4B10.06c, 301 aa; fasta scores: opt: 1112 z-score: 1158.1 E(): 0; 57.3% identity in 288 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (298 aa)
SCO7144SC9A4.06, possible ECF sigma factor, len: 245 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 395 z-score: 475.1 E(): 5.3e-19; 35.0% identity in 197 aa overlap and to SW:RPSH_PSEAE (EMBL:L14760) Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU, 193 aa; fasta scores: opt: 143 z-score: 180.2 E(): 0.014; 26.0% identity in 177 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (245 aa)
SCO7192SC8A11.20, possible sigma factor, len: 221 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 381 z-score: 442.9 E(): 3.4e-17; 39.9% identity in 178 aa overlap; Belongs to the sigma-70 factor family. (221 aa)
SCO7278SC5H1.14, probable RNA polymerase sigma factor, len: 295 aa; similar to many e.g. SW:RPOF_STRCO (EMBL:L11648), SigF, RpoX, Streptomyces coelicolor RNA polymerase sigma-F factor (287 aa), fasta scores; opt: 707 z-score: 817.4 E(): 0, 43.6% identity in 282 aa overlap. Contains probable helix-turn-helix motif at aa 258-279 (Score 2096, +6.33 SD). Contains Pfam match to entry PF00140 sigma70, Sigma-70 factors, score 230.40, E-value 2.6e-65 and PS00715 Sigma-70 factors family signature 1. (295 aa)
SCO7314SC5F8.24, probable RNA polymerase sigma factor, len: 299 aa. Highly similar to many e.g. Streptomyces coelicolor SW:RPOF_STRCO (EMBL:L11648) RNA polymerase sigma-F factor, SigF (287 aa), fasta scores opt: 687 z-score: 772.9 E(): 0 43.6% identity in 275 aa overlap. Contains a Pfam match to entry PF00140 sigma70, Sigma-70 factor and a putative helix-turn-helix motif situated between residues 242..263 (+6.95 SD). (299 aa)
SCO7341SC4G10.20c, sigG, possible RNA polymerase secondary sigma factor, len: 263 aa. Previously sequenced region: Streptomyces coelicolor TR:O52313 (EMBL:AF036131) (263 aa). Highly similar to Streptomyces coelicolor SW:RPOF_STRCO (EMBL:L11648) RNA polymerase sigma-F factor (287 aa), fasta scores opt: 682 z-score: 820.1 E(): 0 49.2% identity in 240 aa overlap. Contains a Prosite hit to PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2 and a Pfam match to entry PF00140 sigma70, Sigma-70 factor. A possible helix-turn-helix motif situated between residues 227..248 (+6.87 SD). (263 aa)
SCP1.116SCP1.116, possible ECF-family sigma factor, len: 380aa; region similar to many eg. TR:Q9RIT1 (EMBL:AJ010584) ECF sigma factor from Streptomyces coelicolor (264 aa) fasta scores; opt: 485, z-score: 519.3, E(): 1.9e-21, 39.0% identity in 223 aa overlap and SW:P35165 (SIGX_BACSU) RNA polymerase sigma factor SigX from Bacillus subtilis (194 aa) fasta scores; opt: 215, z-score: 237.7, E(): 9e-06, 29.0% identity in 162 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Contains a TTA encoded leucine at residue 31, possible target for bldA regulation. (380 aa)
SCP1.151cSCP1.151c, possible sigma factor, len: 174aa; weakly similar to many eg. TR:Q9X8Z1 (EMBL:AL078610) putative ECF sigma factor from Streptomyces coelicolor (184 aa) fasta scores; .opt: 187, z-score: 235.0, E(): 1.3e-05, 28.0% identity in 164 aa overlap and TR:O05767 (EMBL:U87307) SigE, extracytoplasmic function alternative sigma factor from Mycobacterium smegmatis (204 aa) fasta scores; opt: 160, z-score: 202.2, E(): 0.00085, 27.8% identity in 187 aa overlap; Belongs to the sigma-70 factor family. (174 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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