(4 nodes) SnoaL-like domain network (Streptomyces coelicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mmyY	SCP1.229c, mmyY, hypothetical protein, len: 153aa; previously partially sequenced and annotated as TR:Q9JN76 (EMBL:AJ276673). (153 aa)
	SCO5071	SCBAC20F6.14c, ORFA hydroxylacyl-CoA dehydrogenase, len: 146 aa; identical to previously sequenced TR:Q53925 (EMBL:X62373) Streptomyces coelicolor hydroxylacyl-CoA dehydrogenase ORFA, 146 aa. (146 aa)
	SCO2412	SC4A7.40c, possible membrane protein, len: 219 aa; similar to C-terminus of TR:P71415 (EMBL:U75438) Halobacterium salinarium transducer Htd protein, 777 aa; fasta scores: opt: 182 z-score: 198.8 E(): 0.0011; 30.6% identity in 193 aa overlap and to S. coelicolor SC4A7.38c, 253 aa; fasta scores: opt: 323 z-score: 286.8 E(): 1.4e-10; 40.5% identity in 200 aa overlap. (219 aa)
	SCO2411	SC4A7.39c, possible membrane protein, len: 184 aa; similar to various hypothetical proteins, e.g. SW:Y07R_MYCTU (EMBL:Z75555) Mycobacterium tuberculosis hypothetical 28.3 kD protein, 261 aa; fasta scores: opt: 188 z-score: 223.5 E(): 4.6e-05; 28.7% identity in 164 aa overlap and to S/ coelicolor SC4A7.41c, >165 aa; fasta scores: opt: 240 z-score: 255.3 E(): 7.9e-09; 36.0% identity in 161 aa overlap. Contains possible hydrophobic membrane spanning region. (184 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO2411	SCO2412	gene:17760010	gene:17760011	SC4A7.39c, possible membrane protein, len: 184 aa; similar to various hypothetical proteins, e.g. SW:Y07R_MYCTU (EMBL:Z75555) Mycobacterium tuberculosis hypothetical 28.3 kD protein, 261 aa; fasta scores: opt: 188 z-score: 223.5 E(): 4.6e-05; 28.7% identity in 164 aa overlap and to S/ coelicolor SC4A7.41c, >165 aa; fasta scores: opt: 240 z-score: 255.3 E(): 7.9e-09; 36.0% identity in 161 aa overlap. Contains possible hydrophobic membrane spanning region.	SC4A7.40c, possible membrane protein, len: 219 aa; similar to C-terminus of TR:P71415 (EMBL:U75438) Halobacterium salinarium transducer Htd protein, 777 aa; fasta scores: opt: 182 z-score: 198.8 E(): 0.0011; 30.6% identity in 193 aa overlap and to S. coelicolor SC4A7.38c, 253 aa; fasta scores: opt: 323 z-score: 286.8 E(): 1.4e-10; 40.5% identity in 200 aa overlap.	0.963
SCO2412	SCO2411	gene:17760011	gene:17760010	SC4A7.40c, possible membrane protein, len: 219 aa; similar to C-terminus of TR:P71415 (EMBL:U75438) Halobacterium salinarium transducer Htd protein, 777 aa; fasta scores: opt: 182 z-score: 198.8 E(): 0.0011; 30.6% identity in 193 aa overlap and to S. coelicolor SC4A7.38c, 253 aa; fasta scores: opt: 323 z-score: 286.8 E(): 1.4e-10; 40.5% identity in 200 aa overlap.	SC4A7.39c, possible membrane protein, len: 184 aa; similar to various hypothetical proteins, e.g. SW:Y07R_MYCTU (EMBL:Z75555) Mycobacterium tuberculosis hypothetical 28.3 kD protein, 261 aa; fasta scores: opt: 188 z-score: 223.5 E(): 4.6e-05; 28.7% identity in 164 aa overlap and to S/ coelicolor SC4A7.41c, >165 aa; fasta scores: opt: 240 z-score: 255.3 E(): 7.9e-09; 36.0% identity in 161 aa overlap. Contains possible hydrophobic membrane spanning region.	0.963