(12 nodes) (2013) Dual positive feedback regulation of protein degradation of an extra-cytoplasmic function sigma factor for cell differentiation in Streptomyces coelicolor. network (Streptomyces coelicolor)

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Your Input:
	SCO4938	SCK13.30, possible ECF-sigma factor, len: 304 aa; similar to TR:Q9RJS2 (EMBL:AL132707) Streptomyces coelicolor putative RNA polymerase sigma factor SCF51.13c, 298 aa; fasta scores: opt: 1110 z-score: 1299.2 E(): 0; 58.4% identity in 296 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 144..165 (+2.59 SD). (304 aa)
	SCO7144	SC9A4.06, possible ECF sigma factor, len: 245 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 395 z-score: 475.1 E(): 5.3e-19; 35.0% identity in 197 aa overlap and to SW:RPSH_PSEAE (EMBL:L14760) Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU, 193 aa; fasta scores: opt: 143 z-score: 180.2 E(): 0.014; 26.0% identity in 177 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (245 aa)
	SCO4769	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
	SCO0159	SCJ1.08 putative ECF sigma factor, len: 322 aa, similar to many e.g. S. coelicolor TR:CAB44418 (EMBL:AL078610) putative ECF sigma factor SCH35.09 (223 aa) fasta scores, opt: 656 z-score: 777.0 E(): 0 64.6% identity in 175 aa overlap and Mycobacterium tuberculosis SIGI protein TR:O50445 (EMBL; AL010186)(290 aa), fasta scores opt: 385 z-score: 458.0 E(): 3.7e-18 30.0% identity in 290 aa overlap. Contains a Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Possible helix-turn-helix motif between 142-163 aa, score +4.11 SD. (322 aa)
	SCO1263	2SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (295 aa)
	SCO2619	ATP dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). Probably partially responsible for degradation of ECF sigma factor SigR prime; Belongs to the peptidase S14 family. (219 aa)
	SCO3356	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme. (177 aa)
	SCO3709	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family. (184 aa)
	SCO3715	SCH35.09, possible ECF sigma factor, len: 223aa; similar to many egs. TR:O53378 (EMBL:AL021841) putative sigma factor from Mycobacterium tuberculosis (312 aa) fasta scores; opt: 357, z-score: 418.3, E(): 5.7e-16, (33.2% identity in 226 aa overlap) and SW:RPOE_STRCO sigma factor E from Streptomyces coelicolor (176 aa) fasta scores; opt: 131, z-score: 162.5, E(): 0.1, (33.3% identity in 114 aa overlap). NB. Overlaps with downstream CDS. (223 aa)
	SCO3892	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13. (236 aa)
	SCO4864	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (225 aa)
	SCO4866	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (220 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO1263	SCO3892	gene:17758846	gene:17761519	2SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	0.696
SCO3356	SCO3892	gene:17760978	gene:17761519	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	0.896
SCO3356	SCO4769	gene:17760978	gene:17762418	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	0.502
SCO3356	SCO4864	gene:17760978	gene:17762513	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.606
SCO3356	SCO4866	gene:17760978	gene:17762515	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.664
SCO3709	SCO3892	gene:17761333	gene:17761519	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	0.900
SCO3709	SCO4864	gene:17761333	gene:17762513	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.470
SCO3709	SCO4866	gene:17761333	gene:17762515	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.685
SCO3715	SCO3892	gene:17761339	gene:17761519	SCH35.09, possible ECF sigma factor, len: 223aa; similar to many egs. TR:O53378 (EMBL:AL021841) putative sigma factor from Mycobacterium tuberculosis (312 aa) fasta scores; opt: 357, z-score: 418.3, E(): 5.7e-16, (33.2% identity in 226 aa overlap) and SW:RPOE_STRCO sigma factor E from Streptomyces coelicolor (176 aa) fasta scores; opt: 131, z-score: 162.5, E(): 0.1, (33.3% identity in 114 aa overlap). NB. Overlaps with downstream CDS.	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	0.650
SCO3892	SCO1263	gene:17761519	gene:17758846	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	2SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.696
SCO3892	SCO3356	gene:17761519	gene:17760978	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	0.896
SCO3892	SCO3709	gene:17761519	gene:17761333	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	0.900
SCO3892	SCO3715	gene:17761519	gene:17761339	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCH35.09, possible ECF sigma factor, len: 223aa; similar to many egs. TR:O53378 (EMBL:AL021841) putative sigma factor from Mycobacterium tuberculosis (312 aa) fasta scores; opt: 357, z-score: 418.3, E(): 5.7e-16, (33.2% identity in 226 aa overlap) and SW:RPOE_STRCO sigma factor E from Streptomyces coelicolor (176 aa) fasta scores; opt: 131, z-score: 162.5, E(): 0.1, (33.3% identity in 114 aa overlap). NB. Overlaps with downstream CDS.	0.650
SCO3892	SCO4769	gene:17761519	gene:17762418	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	0.911
SCO3892	SCO4864	gene:17761519	gene:17762513	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.841
SCO3892	SCO4866	gene:17761519	gene:17762515	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.912
SCO3892	SCO4938	gene:17761519	gene:17762587	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SCK13.30, possible ECF-sigma factor, len: 304 aa; similar to TR:Q9RJS2 (EMBL:AL132707) Streptomyces coelicolor putative RNA polymerase sigma factor SCF51.13c, 298 aa; fasta scores: opt: 1110 z-score: 1299.2 E(): 0; 58.4% identity in 296 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 144..165 (+2.59 SD).	0.695
SCO3892	SCO7144	gene:17761519	gene:17764804	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	SC9A4.06, possible ECF sigma factor, len: 245 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 395 z-score: 475.1 E(): 5.3e-19; 35.0% identity in 197 aa overlap and to SW:RPSH_PSEAE (EMBL:L14760) Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU, 193 aa; fasta scores: opt: 143 z-score: 180.2 E(): 0.014; 26.0% identity in 177 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.650
SCO4769	SCO3356	gene:17762418	gene:17760978	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	0.502
SCO4769	SCO3892	gene:17762418	gene:17761519	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	SCH24.14c, sigT, probable RNA polymerase sigma factor, len: 236 aa; previously sequenced as TR:O86856 (EMBL:AJ007313), SigT. Similar to other S.coelicolor putative sigma factors TR:O54163 (EMBL:AL021411) possible sigma factor (200 aa) (32.2% identity in 199 aa overlap) and SCH10.35 putative RNA polymerase sigma factor from cosmid StH10 (294 aa) (37.7% identity in 159 aa overlap). Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily), score 57.10, E-value 3.8e-13.	0.911