(12 nodes) (2017) Themes and variations in gene regulation by extracytoplasmic function (ECF) sigma factors. network (Streptomyces coelicolor)

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	SCO4769	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
	SCO4864	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (225 aa)
	SCO4866	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (220 aa)
	SCO4938	SCK13.30, possible ECF-sigma factor, len: 304 aa; similar to TR:Q9RJS2 (EMBL:AL132707) Streptomyces coelicolor putative RNA polymerase sigma factor SCF51.13c, 298 aa; fasta scores: opt: 1110 z-score: 1299.2 E(): 0; 58.4% identity in 296 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily) and possible helix-turn-helix motif at residues 144..165 (+2.59 SD). (304 aa)
	SCO5217	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress. (105 aa)
	SCO7144	SC9A4.06, possible ECF sigma factor, len: 245 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 395 z-score: 475.1 E(): 5.3e-19; 35.0% identity in 197 aa overlap and to SW:RPSH_PSEAE (EMBL:L14760) Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU, 193 aa; fasta scores: opt: 143 z-score: 180.2 E(): 0.014; 26.0% identity in 177 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (245 aa)
	SCO0159	SCJ1.08 putative ECF sigma factor, len: 322 aa, similar to many e.g. S. coelicolor TR:CAB44418 (EMBL:AL078610) putative ECF sigma factor SCH35.09 (223 aa) fasta scores, opt: 656 z-score: 777.0 E(): 0 64.6% identity in 175 aa overlap and Mycobacterium tuberculosis SIGI protein TR:O50445 (EMBL; AL010186)(290 aa), fasta scores opt: 385 z-score: 458.0 E(): 3.7e-18 30.0% identity in 290 aa overlap. Contains a Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Possible helix-turn-helix motif between 142-163 aa, score +4.11 SD. (322 aa)
	SCO3709	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family. (184 aa)
	SCO3715	SCH35.09, possible ECF sigma factor, len: 223aa; similar to many egs. TR:O53378 (EMBL:AL021841) putative sigma factor from Mycobacterium tuberculosis (312 aa) fasta scores; opt: 357, z-score: 418.3, E(): 5.7e-16, (33.2% identity in 226 aa overlap) and SW:RPOE_STRCO sigma factor E from Streptomyces coelicolor (176 aa) fasta scores; opt: 131, z-score: 162.5, E(): 0.1, (33.3% identity in 114 aa overlap). NB. Overlaps with downstream CDS. (223 aa)
	SCO1263	2SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). (295 aa)
	SCO3149	Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (286 aa)
	SCO3356	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme. (177 aa)

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO0159	SCO5217	gene:17757743	gene:17762868	SCJ1.08 putative ECF sigma factor, len: 322 aa, similar to many e.g. S. coelicolor TR:CAB44418 (EMBL:AL078610) putative ECF sigma factor SCH35.09 (223 aa) fasta scores, opt: 656 z-score: 777.0 E(): 0 64.6% identity in 175 aa overlap and Mycobacterium tuberculosis SIGI protein TR:O50445 (EMBL; AL010186)(290 aa), fasta scores opt: 385 z-score: 458.0 E(): 3.7e-18 30.0% identity in 290 aa overlap. Contains a Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Possible helix-turn-helix motif between 142-163 aa, score +4.11 SD.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO1263	SCO5217	gene:17758846	gene:17762868	2SCG18.10c, probable ECF-sigma factor, len: 295 aa; similar to TR:Q9RDI5 (EMBL:AL136519) Streptomyces coelicolor putative sigma factor SCC57A.13c, 315 aa; fasta scores: opt: 887 z-score: 1027.2 E(): 0; 50.5% identity in 285 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO3149	SCO5217	gene:17760766	gene:17762868	Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.418
SCO3356	SCO4769	gene:17760978	gene:17762418	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	0.502
SCO3356	SCO4864	gene:17760978	gene:17762513	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.606
SCO3356	SCO4866	gene:17760978	gene:17762515	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.664
SCO3356	SCO5217	gene:17760978	gene:17762868	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO3709	SCO4864	gene:17761333	gene:17762513	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.470
SCO3709	SCO4866	gene:17761333	gene:17762515	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.685
SCO3709	SCO5217	gene:17761333	gene:17762868	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO3715	SCO5217	gene:17761339	gene:17762868	SCH35.09, possible ECF sigma factor, len: 223aa; similar to many egs. TR:O53378 (EMBL:AL021841) putative sigma factor from Mycobacterium tuberculosis (312 aa) fasta scores; opt: 357, z-score: 418.3, E(): 5.7e-16, (33.2% identity in 226 aa overlap) and SW:RPOE_STRCO sigma factor E from Streptomyces coelicolor (176 aa) fasta scores; opt: 131, z-score: 162.5, E(): 0.1, (33.3% identity in 114 aa overlap). NB. Overlaps with downstream CDS.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO4769	SCO3356	gene:17762418	gene:17760978	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	0.502
SCO4769	SCO5217	gene:17762418	gene:17762868	SCD63.01, ECF sigma factor, len: 195 aa; identical to previously sequenced TR:O86843 (EMBL:AJ010601) Streptomyces coelicolor ECF sigma factor, 195 aa; Belongs to the sigma-70 factor family. ECF subfamily.	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.760
SCO4864	SCO3356	gene:17762513	gene:17760978	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	0.606
SCO4864	SCO3709	gene:17762513	gene:17761333	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	0.470
SCO4864	SCO4866	gene:17762513	gene:17762515	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.736
SCO4864	SCO5217	gene:17762513	gene:17762868	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	Anti-sigma factor; A redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigR, and a key sensor of disulfide stress. Holds SigR, its cognate ECF sigma factor, in an inactive form, inhibiting its sigma activity under reducing but not oxidizing conditions; oxidation and reduction of the anti-sigma factor is reversible. Mycothiol (MSH) is competent for reduction of RsrA, allowing it to bind to SigR. In conjunction with its cognate sigma factor SigR may sense the intracellular level of reduced MSH. Probably releases SigR during oxidative stress.	0.727
SCO4866	SCO3356	gene:17762515	gene:17760978	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	ECF sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall- related functions. It is also involved in the transcription of the dagA gene coding for an extracellular agar-degrading enzyme.	0.664
SCO4866	SCO3709	gene:17762515	gene:17761333	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	SCH35.15, possible ECF sigma factor, len: 184 aa; similar to many e.g. SW:RPOE_STRCO sigma E from Streptomyces coelicolor (176 aa) fasta scores; opt: 216, z-score: 250.5, E(): 1.3e-06, (29.2% identity in 161 aa overlap); Belongs to the sigma-70 factor family.	0.685
SCO4866	SCO4864	gene:17762515	gene:17762513	SCK20.07, possible ECF sigma factor, len: 220 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 280 z-score: 329.1 E(): 8.5e-11; 31.9% identity in 182 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.05, 225 aa; fasta scores: opt: 671 z-score: 614.8 E(): 1.4e-28; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	SCK20.05, possible ECF sigma factor, len: 225 aa; similar to TR:Q9RIT1 (EMBL:AJ010584) Streptomyces coelicolor ECF sigma factor, 264 aa; fasta scores: opt: 296 z-score: 342.7 E(): 1.5e-11; 34.0% identity in 212 aa overlap and to Streptomyces coelicolor putative ECF sigma factor SCK20.07, 220 aa; fasta scores: opt: 671 z-score: 656.4 E(): 6.9e-31; 59.5% identity in 185 aa overlap. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).	0.736