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SCO2086 SCO2086 SCO2087 SCO2087 SCO3926 SCO3926 SCO4745 SCO4745 SCO4542 SCO4542 SCO1541 SCO1541 SCO2076 SCO2076 SCO2080 SCO2080 SCO5877 SCO5877 SCO6436 SCO6436 SCO2082 SCO2082 SCO2083 SCO2083 SCO2084 SCO2084 SCO2085 SCO2085
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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SCO2086Putative UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa)
SCO2087Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (363 aa)
SCO3926SCQ11.09, ssgA, probable regulator, len: 136 aa; highly similar to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus protein associated with sporulation and cell division (136 aa), fasta scores; opt: 715 z-score: 896.6 E(): 0, 77.9% identity in 136 aa overlap and similar to others from S.coelicolor e.g. SC5F2A.05c (EMBL:AL049587) possible regulator (138 aa) (35.7% identity in 115 aa overlap) and SC5H1.03 (EMBL:AL049863) possible regulator (142 aa) (2.5% identity in 114 aa overlap), both annotated by similarity to Streptomyces griseus SsgA. The start codon was selected by similarity t [...] (136 aa)
SCO4745Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (391 aa)
SCO45422SCD4.13c, hypothetical protein, len: 63 aa; identical to previously sequenced TR:Q9XD97 (EMBL:AF106004) Streptomyces coelicolor putative BldB homolog hypothetical 6.8 kDa protein, 63 aa and to TR:Q9RDI7 (EMBL:AL136519) Streptomyces coelicolor hypothetical 7.1 kDa protein SCC57A.10c, 65 aa; fasta scores: opt: 237 z-score: 357.1 E(): 2e-12; 64.8% identity in 54 aa overlap. (63 aa)
SCO1541Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. (159 aa)
SCO2076Putative isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1047 aa)
SCO2080Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (239 aa)
SCO5877Transcriptional regulator RedD; The RedD protein is probably one of several delicately balanced regulatory factors that contribute to the control of the biosynthesis of the antibiotic undecylprodigiosin (Red) in S.coelicolor. (350 aa)
SCO6436SC9B5.03, probable tRNA synthetase, len: 506 aa; similar to many eg. SW:SYM_METTH methionyl-tRNA synthetase from Methanobacterium thermoautotrophicum (651 aa) fasta scores; opt: 610, z-score: 560.9, E(): 5.9e-24, (28.9% identity in 402 aa overlap). Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. (506 aa)
SCO2082Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (399 aa)
SCO2083Sporulation protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (264 aa)
SCO2084UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (364 aa)
SCO2085SC4A10.18c, ftsW, probable cell division protein, len; 456 aa; previously sequenced as TR:Q9ZBA6 (EMBL:U10879), ftsW, Streptomyces coelicolor ftsW protein (456 aa) and identical to that sequence. Similar to many members of the ftsW/rodA/spoVE family e.g. SW:SP5E_BACSU (EMBL:X51419), spoVE, Bacillus subtilis stage V sporulation protein (366 aa), fasta scores; opt: 745 z-score: 788.4 E(): 0, 36.9% identity in 350 aa overlap. Shows similarity to SC6G9.31 (EMBL:AL079356) S.coelicolor probable integral membrane cell-cycle protein (446 aa) (30.0% identity in 416 aa overlap) and SCH69.16 (EMB [...] (456 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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