STRINGSTRING
SCO0565 SCO0565 SCO5250 SCO5250 SCO0568 SCO0568
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO0565SCF73.12c, probable polyprenyl synthetase, len: 352 aa; similar to members of the FPP/GGPP synthetases family e.g. GGPP_MYCTU probable geranylgeranyl pyrophosphate synthetase (359 aa), fasta scores; opt: 253 z-score: 299.8 E(): 2.5e-09 30.1% identity in 346 aa overlap, and ISPB_ECOLI octaprenyl-diphosphate synthase (323 aa), fasta scores; opt: 222 z-score: 264.3 E(): 2.4e-07, 30.0% identity in 337 aa overlap. Contains PS00444 Polyprenyl synthetases signature 2, and Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases. (352 aa)
SCO52502SC7G11.12, gtr, polyprenyl synthetase, len: 386 aa; previously sequenced as TR:Q9RGW1 (EMBL:AF104994) Streptomyces coelicolor A3(2) geranyl transferase Gtr, 386 aa. Contains Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetases and match to Prosite entry PS00723 Polyprenyl synthetases signature 1; Belongs to the FPP/GGPP synthase family. (386 aa)
SCO0568St8B3.02c, possible polyprenyl synthetase, len: 279 aa: similar to many e.g. TR:Q54193 (EMBL:L37405) geranylgeranyl pyrophosphate synthase from Streptomyces griseus (425 aa) fasta scores; opt: 479, Z-score: 544.9, 36.242% identity (38.710% ungapped) in 298 aa overlap and SW:P22939 (ISPA_ECOLI) geranyltransferase from Escherichia coli (299 aa) fasta scores; opt: 350, Z-score: 401.9, 31.939% identity (34.855% ungapped) in 263 aa overlap. Contains Prosite match to PS00723 Polyprenyl synthetases signature 1 and Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetase. (357 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (14%) [HD]