node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0560 | SCO5254 | gene:17758143 | gene:17762905 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | 0.639 |
SCO2082 | SCO5572 | gene:17759680 | gene:17763230 | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. May modulate key aspects of gene expression as its absence has extensive effects on the abundance of about 200 different transcripts. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. Belongs to the ribonuclease III family. | 0.432 |
SCO4808 | SCO5044 | gene:17762457 | gene:17762693 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.809 |
SCO4808 | SCO6585 | gene:17762457 | gene:17764242 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.902 |
SCO5044 | SCO4808 | gene:17762693 | gene:17762457 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.809 |
SCO5044 | SCO5424 | gene:17762693 | gene:17763076 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.589 |
SCO5044 | SCO6585 | gene:17762693 | gene:17764242 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.745 |
SCO5254 | SCO0560 | gene:17762905 | gene:17758143 | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | 0.639 |
SCO5254 | SCO5668 | gene:17762905 | gene:17763324 | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | Putative polyamine ABC-transporter ATP-binding p rotein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | 0.667 |
SCO5254 | SCO5739 | gene:17762905 | gene:17763395 | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.644 |
SCO5424 | SCO5044 | gene:17763076 | gene:17762693 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.589 |
SCO5572 | SCO2082 | gene:17763230 | gene:17759680 | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. May modulate key aspects of gene expression as its absence has extensive effects on the abundance of about 200 different transcripts. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. Belongs to the ribonuclease III family. | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.432 |
SCO5668 | SCO5254 | gene:17763324 | gene:17762905 | Putative polyamine ABC-transporter ATP-binding p rotein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | 0.667 |
SCO5668 | SCO5739 | gene:17763324 | gene:17763395 | Putative polyamine ABC-transporter ATP-binding p rotein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.687 |
SCO5739 | SCO5254 | gene:17763395 | gene:17762905 | Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 2SC7G11.16c, sodN, superoxide dismutase, len: 131 aa; previously sequenced as TR:O51921 (EMBL:AF104994) Streptomyces coelicolor superoxide dismutase (EC 1.15.1.1) SodN, 131 aa; Belongs to the nickel superoxide dismutase family. | 0.644 |
SCO5739 | SCO5668 | gene:17763395 | gene:17763324 | Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | Putative polyamine ABC-transporter ATP-binding p rotein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | 0.687 |
SCO6585 | SCO4808 | gene:17764242 | gene:17762457 | Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.902 |
SCO6585 | SCO5044 | gene:17764242 | gene:17762693 | Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.745 |