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SCO4855 SCO4855 SCO5425 SCO5425 SCO0546 SCO0546 SCO5424 SCO5424 SCO5107 SCO5107 SCO4889 SCO4889 SCO4856 SCO4856 SCO5680 SCO5680 SCO5440 SCO5440 SCO0923 SCO0923
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCO4855SC5G8.23c, dhsB, probable succinate dehydrogenase iron-sulfur subunit, len: 257aa; strongly similar to many eg. SW:P07014 (DHSB_ECOLI) succinate dehydrogenase iron-sulfur protein from Escherichia coli (238 aa) fasta scores; opt: 729, z-score: 839.1, E(): 0, 44.3% identity in 237 aa overlap. Contains Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domains, Pfam match to entry PF00037 fer4, 4Fe-4S ferredoxins and related iron-sulfur cluster binding domains and Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature; Belongs to the succinate [...] (257 aa)
SCO5425Phosphate acetyltransferase (fragment); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
SCO0546Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1124 aa)
SCO5424Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa)
SCO5107SCBAC31E11.03c, shdA2, probable succinate dehydrogenase flavoprotein subunit, len: 653 aa; highly similar to TR:AAK44480 (EMBL:AE006934) Mycobacterium tuberculosis CDC1551 FAD flavoprotein oxidase, putative MT0262, 646 aa; fasta scores: opt: 2941 Z-score: 3164.4 bits: 595.8 E(): 1.2e-168; 70.416% identity in 649 aa overlap and to SW:DHSA_RICPR (EMBL:M88696) Rickettsia prowazekii succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) SdhA, 596 aa; fasta scores: opt: 643 Z-score: 693.1 bits: 138.4 E(): 5.4e-31; 35.218% identity; in 619 aa overlap. Contains Pfam matches to entries PF0 [...] (653 aa)
SCO48892SCK8.15, probable cytidine deaminase, len: 130 aa; similar to SW:CDD_HUMAN (EMBL:L27943) Homo sapiens cytidine deaminase (EC 3.5.4.5) Cda or Cdd, 146 aa; fasta scores: opt: 297 z-score: 380.0 E(): 1.3e-13; 36.2% identity in 130 aa overlap and to TR:53367 (EMBL:AL021841) Mycobacterium tuberculosis cytidine deaminase Cdd or MTV016.15c, 133 aa; fasta scores: opt: 518 z-score: 652.9 E(): 8.4e-29; 61.1% identity in 126 aa overlap. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region and match to Prosite entry PS00903 Cytidine and de [...] (130 aa)
SCO4856SC5G8.24c, dhsA, probable succinate dehydrogenase flavoprotein subunit, len: 584aa; strongly similar to many eg. SW:P10444 (DHSA_ECOLI) succinate dehydrogenase flavoprotein subunit from Escherichia coli (588 aa) fasta scores; opt: 1842, z-score: 2076.6, E(): 0, 48.4% identity in 591 aa overlap. Contains Pfam match to entry PF00890 FAD_binding_2, FAD binding domain and Prosite match to PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. (584 aa)
SCO5680SC5H4.04c, probable cytidine deaminase, len: 137 aa; similar to TR:O53367 (EMBL:AL021841) Mycobacterium tuberculosis cytidine deaminase Cdd, 133 aa; fasta scores: opt 185 z-score: 244.6 E(): 3.6e-06; 37.4% identity in 115 aa overlap and to SW:CDD_MOUSE (EMBL:AA388666) Mus musculus cytidine deaminase (EC 3.5.4.5) Cdd, 146 aa; fasta scores: opt: 173 z-score: 229.1 E(): 2.6e-05; 29.2% identity in 113 aa overlap. Contains Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region and match to Prosite entry PS00903 Cytidine and deoxycytidylate deam [...] (137 aa)
SCO54401,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (774 aa)
SCO0923SCM10.11c, probable reductase flavoprotein subunit, len: 649 aa; similar to SW:DHSA_BACSU (EMBL:M13470) Bacillus subtilis succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) SdhA, 585 aa;fasta scores: opt: 580 z-score: 658.7 E(): 2.7e-29; 36.8% identity in 609 aa overlap and to SW:FRDA_MYCTU (EMBL:Z74020) Mycobacterium tuberculosis fumarate reductase flavoprotein subunit FrdA, 583 aa; fasta scores: opt: 443 z-score: 503.1 E(): 1.2e-20; 32.2% identity in 574 aa overlap. Contains three Pfam matches to entry Pfam match to entry PF00890 FAD_binding_2, FAD binding domain. (649 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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