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mqo mqo glcB glcB glmS glmS SSIL_0632 SSIL_0632 SSIL_0719 SSIL_0719 SSIL_0760 SSIL_0760 gcvH gcvH gltA gltA gltB gltB lipA lipA SSIL_1086 SSIL_1086 pckA pckA SSIL_1185 SSIL_1185 SSIL_1186 SSIL_1186 mdh mdh murI murI glnA glnA gcvT gcvT gcvPA gcvPA gcvPB gcvPB lipM lipM SSIL_1714 SSIL_1714 SSIL_1715 SSIL_1715 SSIL_1716 SSIL_1716 SSIL_1717 SSIL_1717 SSIL_1874 SSIL_1874 SSIL_2106 SSIL_2106 SSIL_2107 SSIL_2107 SSIL_2222 SSIL_2222 SSIL_2641 SSIL_2641 SSIL_2650 SSIL_2650 glsA glsA SSIL_2691 SSIL_2691 SSIL_2764 SSIL_2764 SSIL_3134 SSIL_3134 SSIL_3151 SSIL_3151 SSIL_3152 SSIL_3152 SSIL_3153 SSIL_3153 pdhA pdhA lipL lipL SSIL_3466 SSIL_3466 fumC fumC SSIL_3764 SSIL_3764 SSIL_3809 SSIL_3809
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mqoPredicted dehydrogenase. (494 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
glmSGlucosamine 6-phosphate synthetase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (599 aa)
SSIL_0632Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (512 aa)
SSIL_0719Lipoate-protein ligase A. (330 aa)
SSIL_0760NADPH-dependent glutamate synthase beta chain. (445 aa)
gcvHGlycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (126 aa)
gltAGlutamate synthase domain 2. (1506 aa)
gltBNADPH-dependent glutamate synthase beta chain. (493 aa)
lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (303 aa)
SSIL_1086Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (414 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
SSIL_1185Citrate synthase; Belongs to the citrate synthase family. (371 aa)
SSIL_1186Isocitrate dehydrogenase. (420 aa)
mdhMalate/lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)
glnAGlutamine synthetase. (444 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (367 aa)
gcvPAGlycine cleavage system protein P, N-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa)
gcvPBGlycine cleavage system protein P, C-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (493 aa)
lipMLipoate-protein ligase A; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (277 aa)
SSIL_1714Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (469 aa)
SSIL_1715Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, alpha subunit. (337 aa)
SSIL_1716Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, beta subunit. (327 aa)
SSIL_1717Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component. (450 aa)
SSIL_1874Thermophilic glucose-6-phosphate isomerase. (279 aa)
SSIL_21062-oxoglutarate dehydrogenase complex, dehydrogenase component. (935 aa)
SSIL_2107Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
SSIL_2222Aconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (898 aa)
SSIL_2641Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (455 aa)
SSIL_2650Malic enzyme. (404 aa)
glsAGlutaminase; Belongs to the glutaminase family. (306 aa)
SSIL_2691Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (445 aa)
SSIL_2764Glutamine synthetase. (452 aa)
SSIL_3134Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa)
SSIL_3151Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (470 aa)
SSIL_3152Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component. (459 aa)
SSIL_3153Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, beta subunit. (325 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
lipLLipoate-protein ligase A; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (275 aa)
SSIL_3466Predicted amidohydrolase. (263 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
SSIL_3764Predicted acetamidase/formamidase. (454 aa)
SSIL_3809Isocitrate lyase. (427 aa)
Your Current Organism:
Solibacillus silvestris
NCBI taxonomy Id: 1002809
Other names: S. silvestris StLB046, Solibacillus silvestris StLB046, Solibacillus silvestris str. StLB046, Solibacillus silvestris strain StLB046
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