STRINGSTRING
SSIL_0493 SSIL_0493 ftsH ftsH SSIL_0113 SSIL_0113 engD engD SSIL_0131 SSIL_0131 SSIL_0185 SSIL_0185 SSIL_0259 SSIL_0259 cshA cshA SSIL_0457 SSIL_0457 SSIL_0486 SSIL_0486 yfmL yfmL SSIL_0630 SSIL_0630 SSIL_0735 SSIL_0735 SSIL_0801 SSIL_0801 SSIL_0812 SSIL_0812 SSIL_0817 SSIL_0817 SSIL_1140 SSIL_1140 deaD deaD mutS2 mutS2 clpX clpX lon lon SSIL_1432 SSIL_1432 minD minD ruvA ruvA ruvB ruvB recD2 recD2 mutL mutL SSIL_1727 SSIL_1727 cadA cadA SSIL_2225 SSIL_2225 SSIL_2437 SSIL_2437 SSIL_2493 SSIL_2493 cshB cshB SSIL_2869 SSIL_2869 fliI fliI hslU hslU smc smc recG recG ftsA ftsA SSIL_3240 SSIL_3240 SSIL_3241 SSIL_3241 addA addA SSIL_3249 SSIL_3249 uvrA uvrA uvrB uvrB SSIL_3482 SSIL_3482 SSIL_3499 SSIL_3499 SSIL_3543 SSIL_3543 SSIL_3768 SSIL_3768
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSIL_0493Superfamily I DNA and RNA helicase. (752 aa)
ftsHATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (679 aa)
SSIL_0113ATPase. (253 aa)
engDPredicted GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
SSIL_0131Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa)
SSIL_0185ATPase with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (814 aa)
SSIL_0259ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (351 aa)
cshASuperfamily II DNA and RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (517 aa)
SSIL_0457MoxR-like ATPase. (313 aa)
SSIL_0486ABC-type multidrug transport system, ATPase component. (258 aa)
yfmLSuperfamily II DNA and RNA helicase. (410 aa)
SSIL_0630Cation transport ATPase. (634 aa)
SSIL_0735Superfamily I DNA and RNA helicase. (671 aa)
SSIL_0801DNA mismatch repair enzyme. (498 aa)
SSIL_0812Replicative DNA helicase. (423 aa)
SSIL_0817Superfamily I DNA and RNA helicase. (374 aa)
SSIL_1140Actin-like ATPase. (718 aa)
deaDSuperfamily II DNA and RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (481 aa)
mutS2Mismatch repair ATPase; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (788 aa)
clpXATP-dependent protease Clp, ATPase subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)
lonATP-dependent Lon protease, bacterial type; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (774 aa)
SSIL_1432Phage-related minor tail protein. (427 aa)
minDSeptum formation inhibitor-activating ATPase. (294 aa)
ruvAHolliday junction resolvasome, DNA-binding subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (251 aa)
ruvBHolliday junction resolvasome, helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
recD2ATP-dependent exoDNAse alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (833 aa)
mutLDNA mismatch repair enzyme; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (629 aa)
SSIL_1727Predicted ATPase. (246 aa)
cadACation transport ATPase. (821 aa)
SSIL_2225MoxR-like ATPase. (372 aa)
SSIL_2437Cation transport ATPase. (797 aa)
SSIL_2493ATP-dependent Lon protease. (295 aa)
cshBSuperfamily II DNA and RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (436 aa)
SSIL_2869Hypothetical protein. (268 aa)
fliIFlagellar biosynthesis/type III secretory pathway ATPase. (441 aa)
hslUATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (463 aa)
smcChromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1193 aa)
recGRecG-like helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (679 aa)
ftsAActin-like ATPase; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (431 aa)
SSIL_3240ATPase with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (709 aa)
SSIL_3241Predicted metal-sulfur cluster biosynthetic enzyme. (104 aa)
addAATP-dependent exoDNAse beta subunit; ATP-dependent DNA helicase. (1239 aa)
SSIL_3249ATP-dependent nuclease, subunit B; ATP-dependent DNA helicase. (1213 aa)
uvrAExcinuclease ATPase subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (955 aa)
uvrBHelicase subunit of the DNA excision repair complex; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the [...] (660 aa)
SSIL_3482Superfamily I DNA and RNA helicase. (786 aa)
SSIL_3499Superfamily I DNA and RNA helicase. (730 aa)
SSIL_3543Superfamily I DNA and RNA helicase. (740 aa)
SSIL_3768Cation transport ATPase. (865 aa)
Your Current Organism:
Solibacillus silvestris
NCBI taxonomy Id: 1002809
Other names: S. silvestris StLB046, Solibacillus silvestris StLB046, Solibacillus silvestris str. StLB046, Solibacillus silvestris strain StLB046
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.