STRINGSTRING
murF murF glmU glmU SSIL_0096 SSIL_0096 SSIL_0108 SSIL_0108 murB murB ddl ddl SSIL_0601 SSIL_0601 amj amj murC murC murI murI SSIL_1331 SSIL_1331 mltG mltG SSIL_1576 SSIL_1576 SSIL_1585 SSIL_1585 SSIL_1619 SSIL_1619 yqgS yqgS SSIL_1688 SSIL_1688 SSIL_1856 SSIL_1856 murG murG msrR msrR SSIL_2185 SSIL_2185 SSIL_2390 SSIL_2390 SSIL_2634 SSIL_2634 SSIL_2735 SSIL_2735 SSIL_2777 SSIL_2777 SSIL_2843 SSIL_2843 SSIL_3019 SSIL_3019 murD murD mraY mraY murE murE murE-2 murE-2 SSIL_3275 SSIL_3275 SSIL_3297 SSIL_3297 SSIL_3298 SSIL_3298 SSIL_3302 SSIL_3302 tagA tagA murA murA SSIL_3379 SSIL_3379 murA-2 murA-2 SSIL_3416 SSIL_3416 uppP uppP uppP-2 uppP-2 SSIL_3733 SSIL_3733
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murFUDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (456 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
SSIL_0096D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (445 aa)
SSIL_0108Predicted RNA-binding protein. (254 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (303 aa)
ddlD-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (357 aa)
SSIL_0601Beta-lactamase class C. (343 aa)
amjHypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (262 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (432 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)
SSIL_1331Cell wall hydrolyses. (146 aa)
mltGPredicted periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (372 aa)
SSIL_1576Cell wall-associated hydrolase. (270 aa)
SSIL_1585Cell division protein FtsI/penicillin-binding protein 2. (736 aa)
SSIL_1619Hypothetical protein. (162 aa)
yqgSPhosphoglycerol transferase. (633 aa)
SSIL_1688Membrane protein. (333 aa)
SSIL_1856Transcriptional regulator. (347 aa)
murGUDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (358 aa)
msrRTranscriptional regulator. (312 aa)
SSIL_2185Uncharacterized protein. (111 aa)
SSIL_2390UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (231 aa)
SSIL_2634Phosphoglycerol transferase; Belongs to the LTA synthase family. (633 aa)
SSIL_2735Cell wall hydrolyses. (260 aa)
SSIL_2777D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (324 aa)
SSIL_2843D-alanyl-D-alanine carboxypeptidase. (472 aa)
SSIL_3019Predicted RNA-binding protein; Belongs to the UPF0109 family. (77 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
mraYUDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murEUDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (493 aa)
murE-2UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (489 aa)
SSIL_3275UDP-N-acetylglucosamine 2-epimerase. (376 aa)
SSIL_3297Transcriptional regulator. (349 aa)
SSIL_3298UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (351 aa)
SSIL_3302Cell wall-associated hydrolase. (327 aa)
tagATeichoic acid biosynthesis protein; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. (240 aa)
murAUDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (433 aa)
SSIL_3379UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (386 aa)
murA-2UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (425 aa)
SSIL_3416FOG: GGDEF domain. (359 aa)
uppPUncharacterized bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (271 aa)
uppP-2Uncharacterized bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (274 aa)
SSIL_3733D-alanyl-D-alanine carboxypeptidase. (464 aa)
Your Current Organism:
Solibacillus silvestris
NCBI taxonomy Id: 1002809
Other names: S. silvestris StLB046, Solibacillus silvestris StLB046, Solibacillus silvestris str. StLB046, Solibacillus silvestris strain StLB046
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