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| | SSIL_0010 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | SSIL_0015 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa) |
| | ipk | 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (288 aa) |
| | SSIL_0064 | FAD synthase. (270 aa) |
| | SSIL_0087 | Isopropylmalate/homocitrate/citramalate synthase. (283 aa) |
| | SSIL_0088 | acyl-CoA dehydrogenase. (388 aa) |
| | SSIL_0095 | Asparagine synthase. (608 aa) |
| | guaB | IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | SSIL_0160 | Threonine dehydrogenase. (379 aa) |
| | mqo | Predicted dehydrogenase. (494 aa) |
| | SSIL_0174 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa) |
| | ispD | 4-diphosphocytidyl-2-methyl-D-erithritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (226 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa) |
| | glcB | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | SSIL_0265 | Arginase/agmatinase/formimionoglutamate hydrolase; Belongs to the arginase family. (301 aa) |
| | yhdO | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (200 aa) |
| | menC | L-alanine-DL-glutamate epimerase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (369 aa) |
| | SSIL_0376 | Uncharacterized enzyme. (110 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (299 aa) |
| | SSIL_0381 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa) |
| | SSIL_0398 | acetyl-CoA hydrolase. (506 aa) |
| | SSIL_0445 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (461 aa) |
| | SSIL_0446 | 5,10-methylenetetrahydrofolate reductase. (614 aa) |
| | SSIL_0447 | Methionine synthase I, cobalamin-binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1143 aa) |
| | SSIL_0452 | Proline dehydrogenase. (323 aa) |
| | purE | Phosphoribosylcarboxyaminoimidazole mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (374 aa) |
| | SSIL_0476 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (236 aa) |
| | yexA | Phosphoribosylformylglycinamidine synthase, PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thoug [...] (81 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ an [...] (227 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase, synthetase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (743 aa) |
| | purF | Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (472 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase. (351 aa) |
| | purN | Folate-dependent phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (190 aa) |
| | purH | AICAR transformylase/IMP cyclohydrolase PurH. (511 aa) |
| | purD | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (416 aa) |
| | SSIL_0517 | Transcriptional regulator/sugar kinase. (287 aa) |
| | SSIL_0521 | Proline dehydrogenase. (324 aa) |
| | SSIL_0530 | Sphingosine kinase. (308 aa) |
| | SSIL_0546 | Zn-dependent alcohol dehydrogenase. (317 aa) |
| | fabG | Dehydrogenase with different specificities. (240 aa) |
| | SSIL_0604 | acyl-CoA dehydrogenase. (380 aa) |
| | SSIL_0628 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. (372 aa) |
| | SSIL_0632 | Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (512 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase. (428 aa) |
| | SSIL_0691 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (541 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (365 aa) |
| | hemE | uroporphyrinogen-III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa) |
| | hemH | Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (310 aa) |
| | SSIL_0714 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (475 aa) |
| | hisZ | ATP phosphoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (386 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (207 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa) |
| | hisF | Imidazoleglycerol-phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | hisIE | phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (205 aa) |
| | SSIL_0773 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa) |
| | pgk | 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | gpmI | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (513 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | katE | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (681 aa) |
| | SSIL_0933 | Methionine synthase II. (367 aa) |
| | dhbA | Dehydrogenase with different specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (262 aa) |
| | SSIL_0947 | Isochorismate synthase. (400 aa) |
| | SSIL_0948 | Isochorismate hydrolase. (221 aa) |
| | SSIL_0952 | Uncharacterized protein. (68 aa) |
| | dhbE | Peptide arylation enzyme. (536 aa) |
| | SSIL_0995 | FAD/FMN-containing dehydrogenase. (468 aa) |
| | SSIL_1033 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | gcvH | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (126 aa) |
| | gltA | Glutamate synthase domain 2. (1506 aa) |
| | gltB | NADPH-dependent glutamate synthase beta chain. (493 aa) |
| | SSIL_1054 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase; Belongs to the 5'-nucleotidase family. (454 aa) |
| | SSIL_1081 | Biproductal PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (392 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (305 aa) |
| | SSIL_1095 | Isochorismate synthase. (460 aa) |
| | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (577 aa) |
| | menH | Predicted hydrolase or acyltransferase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (270 aa) |
| | menB | Dihydroxynaphthoic acid synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (274 aa) |
| | menE | acyl-CoA synthetase/AMP-acid ligase II; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. (478 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (398 aa) |
| | SSIL_1141 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase. (361 aa) |
| | SSIL_1146 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (575 aa) |
| | argC | Acetylglutamate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (407 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (258 aa) |
| | argD | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (383 aa) |
| | SSIL_1159 | Histidinol phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (267 aa) |
| | SSIL_1164 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (520 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa) |
| | accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | SSIL_1185 | Citrate synthase; Belongs to the citrate synthase family. (371 aa) |
| | SSIL_1186 | Isocitrate dehydrogenase. (420 aa) |
| | mdh | Malate/lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | SSIL_1201 | Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa) |
| | SSIL_1222 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (322 aa) |
| | SSIL_1258 | Aspartokinase; Belongs to the aspartokinase family. (410 aa) |
| | SSIL_1260 | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (204 aa) |
| | sdhA | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (581 aa) |
| | sdhB | Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (258 aa) |
| | SSIL_1291 | uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. (259 aa) |
| | SSIL_1292 | Uncharacterized conserved protein. (242 aa) |
| | SSIL_1296 | Siroheme synthase. (212 aa) |
| | SSIL_1338 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase. (787 aa) |
| | SSIL_1363 | Saccharopine dehydrogenase. (409 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (451 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa) |
| | SSIL_1376 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (247 aa) |
| | SSIL_1377 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (326 aa) |
| | hemL-2 | Glutamate-1-semialdehyde aminotransferase. (429 aa) |
| | pheB | ACT domain-containing protein; Belongs to the UPF0735 family. (151 aa) |
| | pheA | Prephenate dehydratase. (290 aa) |
| | SSIL_1499 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide isomerase; Belongs to the HisA/HisF family. (261 aa) |
| | SSIL_1518 | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (179 aa) |
| | SSIL_1519 | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (260 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa) |
| | SSIL_1560 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | ispG | Enzyme; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa) |
| | SSIL_1596 | Alcohol dehydrogenase, class IV. (399 aa) |
| | trpE | Anthranilate/para-aminobenzoate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismat [...] (462 aa) |
| | SSIL_1612 | Anthranilate/para-aminobenzoate synthase component II. (193 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (367 aa) |
| | gcvPA | Glycine cleavage system protein P, N-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa) |
| | gcvPB | Glycine cleavage system protein P, C-terminal domain; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (493 aa) |
| | SSIL_1683 | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (166 aa) |
| | SSIL_1684 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa) |
| | SSIL_1693 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (546 aa) |
| | SSIL_1701 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (294 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa) |
| | SSIL_1713 | Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (364 aa) |
| | SSIL_1714 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (469 aa) |
| | SSIL_1715 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, alpha subunit. (337 aa) |
| | SSIL_1716 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, beta subunit. (327 aa) |
| | SSIL_1717 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component. (450 aa) |
| | SSIL_1723 | acetyl-CoA carboxylase, carboxyltransferase component. (522 aa) |
| | SSIL_1761 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (440 aa) |
| | SSIL_1840 | Dehydrogenase with different specificities. (254 aa) |
| | SSIL_1843 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa) |
| | SSIL_1865 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (547 aa) |
| | SSIL_1880 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa) |
| | SSIL_1949 | Zn-dependent protease with chaperone product. (420 aa) |
| | SSIL_2007 | Riboflavin synthase alpha chain. (211 aa) |
| | ribA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (203 aa) |
| | ribH | Riboflavin synthase beta-chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (154 aa) |
| | SSIL_2032 | 3-hydroxyacyl-CoA dehydrogenase. (297 aa) |
| | SSIL_2037 | Cystathionine beta-lyase/cystathionine gamma-synthase. (387 aa) |
| | SSIL_2038 | Cystathionine beta-lyase/cystathionine gamma-synthase. (371 aa) |
| | ilvD | Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (556 aa) |
| | SSIL_2044 | Thiamine pyrophosphate-requiring enzyme. (582 aa) |
| | SSIL_2045 | Acetolactate synthase, small subunit. (171 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa) |
| | leuB | Isocitrate/isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa) |
| | SSIL_2071 | Predicted phosphatase. (224 aa) |
| | deoD | Purine-nucleoside phosphorylase. (235 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (320 aa) |
| | SSIL_2106 | 2-oxoglutarate dehydrogenase complex, dehydrogenase component. (935 aa) |
| | SSIL_2107 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa) |
| | SSIL_2124 | Aspartate/tyrosine/aromatic aminotransferase. (387 aa) |
| | SSIL_2161 | Dehydrogenase with different specificities. (251 aa) |
| | plsY | Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (200 aa) |
| | metAA | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (313 aa) |
| | SSIL_2196 | acetyl-CoA hydrolase. (506 aa) |
| | ribD | Pyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa) |
| | SSIL_2214 | GTP cyclohydrolase II. (240 aa) |
| | SSIL_2217 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (327 aa) |
| | SSIL_2221 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase; Belongs to the 5'-nucleotidase family. (717 aa) |
| | SSIL_2222 | Aconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (898 aa) |
| | leuA | Isopropylmalate/homocitrate/citramalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (529 aa) |
| | SSIL_2269 | Threonine dehydrogenase. (378 aa) |
| | SSIL_2312 | Catalase; Belongs to the catalase family. (549 aa) |
| | SSIL_2342 | Threonine dehydratase. (319 aa) |
| | argH | Argininosuccinate lyase. (457 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa) |
| | SSIL_2408 | Thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family. (582 aa) |
| | SSIL_2457 | Fructose-2,6-bisphosphatase. (178 aa) |
| | cysG | uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. (253 aa) |
| | SSIL_2484 | Siroheme synthase. (210 aa) |
| | SSIL_2519 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (475 aa) |
| | SSIL_2543 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (664 aa) |
| | SSIL_2559 | Serine acetyltransferase. (309 aa) |
| | SSIL_2585 | Aspartokinase; Belongs to the aspartokinase family. (453 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (360 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | SSIL_2631 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | SSIL_2632 | acyl-CoA dehydrogenase. (391 aa) |
| | SSIL_2633 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (372 aa) |
| | SSIL_2638 | Phytoene/squalene synthetase. (273 aa) |
| | SSIL_2643 | Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (228 aa) |
| | SSIL_2687 | Aspartate/tyrosine/aromatic aminotransferase. (397 aa) |
| | SSIL_2691 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (445 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | panC | Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (287 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (278 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (265 aa) |
| | aroA | 5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa) |
| | SSIL_2710 | Prephenate dehydrogenase. (365 aa) |
| | hisC | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (366 aa) |
| | SSIL_2712 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (120 aa) |
| | aroB | 3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (393 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | SSIL_2720 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (324 aa) |
| | menG | Methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (233 aa) |
| | SSIL_2722 | Hypothetical protein. (246 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (337 aa) |
| | SSIL_2737 | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (321 aa) |
| | SSIL_2744 | Enoyl-[acyl-carrier-protein] reductase. (258 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (439 aa) |
| | SSIL_2798 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | SSIL_2808 | Zn-dependent alcohol dehydrogenase, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (371 aa) |
| | SSIL_2825 | Uncharacterized enzyme. (110 aa) |
| | ywaA | Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (356 aa) |
| | ispH | Penicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (322 aa) |
| | SSIL_2866 | acyl-CoA dehydrogenase. (350 aa) |
| | SSIL_2899 | Phytoene dehydrogenase. (524 aa) |
| | korB | Pyruvate:ferredoxin oxidoreductase. (288 aa) |
| | korA | Pyruvate:ferredoxin oxidoreductase. (577 aa) |
| | SSIL_2927 | Dehydrogenase with different specificities. (242 aa) |
| | dapA | Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (303 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (346 aa) |
| | ribC | FAD synthase; Belongs to the ribF family. (316 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (381 aa) |
| | SSIL_2961 | CDP-diglyceride synthetase; Belongs to the CDS family. (265 aa) |
| | SSIL_2962 | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (264 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | fabG-3 | Dehydrogenase with different specificities; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | SSIL_3035 | (acyl-carrier-protein) S-malonyltransferase. (317 aa) |
| | plsX | Fatty acid/phospholipid biosynthesis enzyme; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (331 aa) |
| | SSIL_3040 | L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (306 aa) |
| | SSIL_3041 | L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa) |
| | SSIL_3047 | Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | SSIL_3108 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (297 aa) |
| | SSIL_3110 | Biotin carboxyl carrier protein. (70 aa) |
| | ctaA | Uncharacterized protein required for cytochrome oxidase assembly; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (303 aa) |
| | SSIL_3143 | Archaeal fructose-1,6-bisphosphatase. (264 aa) |
| | SSIL_3151 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component. (470 aa) |
| | SSIL_3152 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component. (459 aa) |
| | SSIL_3153 | Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, beta subunit. (325 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa) |
| | SSIL_3169 | Metal-dependent amidase/aminoacylase/carboxypeptidase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (373 aa) |
| | dapH | Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (237 aa) |
| | SSIL_3186 | Fe-S oxidoreductase. (577 aa) |
| | SSIL_3201 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (462 aa) |
| | aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa) |
| | SSIL_3243 | Predicted hydrolase of the HAD superfamily. (268 aa) |
| | SSIL_3244 | Glycosidase. (484 aa) |
| | glyA | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa) |
| | SSIL_3383 | Ribose 5-phosphate isomerase RpiB. (146 aa) |
| | glpX | Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase. (321 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (216 aa) |
| | SSIL_3397 | Fructose/tagatose bisphosphate aldolase. (284 aa) |
| | SSIL_3404 | acyl-CoA dehydrogenase. (378 aa) |
| | SSIL_3407 | acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa) |
| | SSIL_3430 | Uncharacterized conserved protein; May function as heme-dependent peroxidase. (245 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa) |
| | SSIL_3449 | Anthranilate/para-aminobenzoate synthase component I. (327 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (205 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (395 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (259 aa) |
| | SSIL_3486 | Gluconolactonase. (326 aa) |
| | SSIL_3495 | Transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain. (388 aa) |
| | plsY-2 | Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (184 aa) |
| | ctaB | Polyprenyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (298 aa) |
| | SSIL_3517 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | SSIL_3578 | Saccharopine dehydrogenase. (390 aa) |
| | SSIL_3589 | Homoserine dehydrogenase. (328 aa) |
| | SSIL_3622 | Sugar kinase, ribokinase family. (312 aa) |
| | fabG-4 | Dehydrogenase with different specificities. (243 aa) |
| | rocD | Ornithine/acetylornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (400 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | xpt | Adenine/guanine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa) |
| | SSIL_3667 | Nitric oxide synthase, oxygenase domain; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily. (359 aa) |
| | SSIL_3684 | Dehydrogenase with different specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | SSIL_3687 | FAD synthase. (261 aa) |
| | SSIL_3705 | Catalase. (496 aa) |
| | SSIL_3757 | Dehydrogenase with different specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (241 aa) |
| | SSIL_3800 | Sugar kinase, ribokinase family. (315 aa) |
| | argH-2 | Argininosuccinate lyase. (507 aa) |
| | SSIL_3809 | Isocitrate lyase. (427 aa) |
