(6 nodes) Peritoneal macrophage network (Cricetulus griseus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	I79_008232	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family. (944 aa)
	Il10	Interleukin-10. (178 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	I79_015109	Interleukin-6. (174 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_008232	I79_015109	G3HCM1	G3HVW6	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	Interleukin-6.	0.491
I79_008232	IL1B	G3HCM1	G3I1B0	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.475
I79_008232	Ifng	G3HCM1	G3GY20	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.503
I79_008232	Il10	G3HCM1	G3HB01	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	Interleukin-10.	0.475
I79_008232	Tlr4	G3HCM1	G3I192	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.435
I79_015109	I79_008232	G3HVW6	G3HCM1	Interleukin-6.	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	0.491
I79_015109	IL1B	G3HVW6	G3I1B0	Interleukin-6.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.955
I79_015109	Ifng	G3HVW6	G3GY20	Interleukin-6.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.878
I79_015109	Il10	G3HVW6	G3HB01	Interleukin-6.	Interleukin-10.	0.926
I79_015109	Tlr4	G3HVW6	G3I192	Interleukin-6.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.830
IL1B	I79_008232	G3I1B0	G3HCM1	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	0.475
IL1B	I79_015109	G3I1B0	G3HVW6	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-6.	0.955
IL1B	Ifng	G3I1B0	G3GY20	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.900
IL1B	Il10	G3I1B0	G3HB01	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-10.	0.937
IL1B	Tlr4	G3I1B0	G3I192	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.852
Ifng	I79_008232	G3GY20	G3HCM1	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family.	0.503
Ifng	I79_015109	G3GY20	G3HVW6	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-6.	0.878
Ifng	IL1B	G3GY20	G3I1B0	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.900
Ifng	Il10	G3GY20	G3HB01	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-10.	0.979
Ifng	Tlr4	G3GY20	G3I192	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.893