(25 nodes) Ileocecum network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ttc38	Tetratricopeptide repeat protein 38. (465 aa)
	Gpbar1	G-protein coupled bile acid receptor 1. (316 aa)
	Trpc4	Short transient receptor potential channel 4-like protein; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
	I79_020586	Cdc42 effector protein 4. (243 aa)
	Fam13a	Protein FAM13A. (692 aa)
	Fgf19	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
	Slc10a2	Ileal sodium/bile acid cotransporter. (348 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	I79_015109	Interleukin-6. (174 aa)
	Tmem260	UPF0679 protein C14orf101-like. (551 aa)
	Naaladl1	N-acetylated-alpha-linked acidic dipeptidase-like protein. (746 aa)
	C1H14orf119	Uncharacterized protein C14orf119-like. (142 aa)
	Cdc42ep4	Cdc42 effector protein 4. (358 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Hebp2	Heme-binding protein 2. (205 aa)
	Dhx35	Putative ATP-dependent RNA helicase DHX35. (703 aa)
	Mllt6	Protein AF-17. (976 aa)
	Cog4	Conserved oligomeric Golgi complex subunit 4. (785 aa)
	I79_010756	Galectin. (283 aa)
	Il10	Interleukin-10. (178 aa)
	Cyp7a1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
	Slitrk6	SLIT and NTRK-like protein 6. (817 aa)
	Dcaf10	WD repeat-containing protein 32. (151 aa)
	I79_012610	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (865 aa)
	Pex26	Peroxisome assembly protein 26. (301 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	I79_015109	G3GUN9	G3HVW6	T-cell surface glycoprotein CD4.	Interleukin-6.	0.849
Cd4	IL1B	G3GUN9	G3I1B0	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.872
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cyp7a1	Fgf19	G3HD58	G3I4D9	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family.	0.759
Cyp7a1	Gpbar1	G3HD58	G3IEK3	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	G-protein coupled bile acid receptor 1.	0.454
Cyp7a1	Slc10a2	G3HD58	G3I3N2	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Ileal sodium/bile acid cotransporter.	0.590
Fgf19	Cyp7a1	G3I4D9	G3HD58	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.759
Fgf19	Gpbar1	G3I4D9	G3IEK3	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family.	G-protein coupled bile acid receptor 1.	0.472
Fgf19	Slc10a2	G3I4D9	G3I3N2	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family.	Ileal sodium/bile acid cotransporter.	0.519
Gpbar1	Cyp7a1	G3IEK3	G3HD58	G-protein coupled bile acid receptor 1.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.454
Gpbar1	Fgf19	G3IEK3	G3I4D9	G-protein coupled bile acid receptor 1.	Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family.	0.472
I79_012610	Trpc4	G3HPA2	G3ID96	Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family.	Short transient receptor potential channel 4-like protein; Belongs to the transient receptor (TC 1.A.4) family.	0.688
I79_015109	Cd4	G3HVW6	G3GUN9	Interleukin-6.	T-cell surface glycoprotein CD4.	0.849
I79_015109	IL1B	G3HVW6	G3I1B0	Interleukin-6.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.955
I79_015109	Il10	G3HVW6	G3HB01	Interleukin-6.	Interleukin-10.	0.926
IL1B	Cd4	G3I1B0	G3GUN9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	T-cell surface glycoprotein CD4.	0.872
IL1B	I79_015109	G3I1B0	G3HVW6	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-6.	0.955
IL1B	Il10	G3I1B0	G3HB01	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-10.	0.937
Il10	Cd4	G3HB01	G3GUN9	Interleukin-10.	T-cell surface glycoprotein CD4.	0.968
Il10	I79_015109	G3HB01	G3HVW6	Interleukin-10.	Interleukin-6.	0.926