STRINGSTRING
I79_000303 I79_000303 Suclg2 Suclg2 I79_000846 I79_000846 Eno2 Eno2 I79_001790 I79_001790 Urb2 Urb2 Pdhx Pdhx Got1 Got1 Idh3a Idh3a I79_003584 I79_003584 Got1l1 Got1l1 Dlat Dlat Pkm Pkm Idh3b Idh3b PDH-A1 PDH-A1 Fh Fh I79_006148 I79_006148 H671_1g1921 H671_1g1921 I79_007263 I79_007263 Pck1 Pck1 Pklr Pklr Pck2 Pck2 Mdh1 Mdh1 I79_009335 I79_009335 I79_009378 I79_009378 Dlst Dlst CgPICR_011466 CgPICR_011466 I79_009564 I79_009564 I79_009741 I79_009741 Ldhb Ldhb I79_009945 I79_009945 Ilvbl Ilvbl Ogdh Ogdh Nit2 Nit2 I79_012728 I79_012728 SUCLG1 SUCLG1 I79_013031 I79_013031 I79_013121 I79_013121 I79_013257 I79_013257 Cs Cs Idh3g Idh3g I79_014005 I79_014005 I79_014006 I79_014006 Me2 Me2 Sdhc Sdhc Idh1 Idh1 I79_014552 I79_014552 Gpt Gpt I79_015837 I79_015837 I79_016125 I79_016125 Sucla2 Sucla2 Bcat2 Bcat2 I79_016905 I79_016905 I79_016906 I79_016906 I79_016907 I79_016907 I79_017481 I79_017481 Dld Dld Got2 Got2 PC PC I79_018485 I79_018485 Il4i1 Il4i1 Gpt2 Gpt2 CgPICR_015813 CgPICR_015813 Bckdha Bckdha Sdhb Sdhb Sdha Sdha I79_022787 I79_022787 Idh2 Idh2 Aco2 Aco2 I79_023874 I79_023874 I79_024231 I79_024231 I79_025699 I79_025699 Acly Acly I79_026075 I79_026075
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000303Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (385 aa)
Suclg2Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial. (358 aa)
I79_000846NADP-dependent malic enzyme, mitochondrial. (134 aa)
Eno2Gamma-enolase. (434 aa)
I79_001790Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial. (494 aa)
Urb2Unhealthy ribosome biogenesis protein 2-like. (1522 aa)
PdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
Got1Aspartate aminotransferase. (413 aa)
Idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
I79_003584L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. (156 aa)
Got1l1Putative aspartate aminotransferase, cytoplasmic 2. (791 aa)
DlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (646 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
Idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
PDH-A1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
FhFumarate hydratase, mitochondrial. (507 aa)
I79_0061482-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (221 aa)
H671_1g1921Dihydrolipoyl dehydrogenase, mitochondrial. (180 aa)
I79_007263Malate dehydrogenase. (271 aa)
Pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
PklrPyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
Pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
Mdh1Malate dehydrogenase. (334 aa)
I79_009335Amine oxidase. (503 aa)
I79_009378ATP-binding cassette sub-family G member 3. (620 aa)
DlstDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (308 aa)
CgPICR_011466L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (382 aa)
I79_009564Citrate synthase, mitochondrial. (380 aa)
I79_009741L-lactate dehydrogenase A chain. (112 aa)
LdhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
I79_009945Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial. (123 aa)
IlvblAcetolactate synthase-like protein; Belongs to the TPP enzyme family. (632 aa)
Ogdh2-oxoglutarate dehydrogenase E1 component, mitochondrial. (917 aa)
Nit2Omega-amidase NIT2. (276 aa)
I79_012728L-lactate dehydrogenase A chain. (137 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (333 aa)
I79_013031L-lactate dehydrogenase A chain. (94 aa)
I79_013121Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (565 aa)
I79_013257Cytoplasmic aconitate hydratase. (808 aa)
CsCitrate synthase; Belongs to the citrate synthase family. (313 aa)
Idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (335 aa)
I79_014005L-lactate dehydrogenase A chain. (119 aa)
I79_014006L-lactate dehydrogenase A chain. (84 aa)
Me2Malic enzyme. (584 aa)
SdhcSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (132 aa)
Idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
I79_014552Isocitrate dehydrogenase [NADP] cytoplasmic. (112 aa)
GptAlanine aminotransferase 1. (481 aa)
I79_015837Malic enzyme. (437 aa)
I79_016125Pyruvate kinase isozymes M1/M2. (110 aa)
Sucla2Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial. (238 aa)
Bcat2Branched-chain-amino-acid aminotransferase, mitochondrial. (783 aa)
I79_016905annotation not available (116 aa)
I79_016906annotation not available (61 aa)
I79_016907annotation not available (117 aa)
I79_017481L-lactate dehydrogenase C chain; Belongs to the LDH/MDH superfamily. (274 aa)
DldDihydrolipoyl dehydrogenase. (509 aa)
Got2Aspartate aminotransferase. (430 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
I79_018485Isocitrate dehydrogenase [NADP] cytoplasmic. (235 aa)
Il4i1L-amino-acid oxidase. (413 aa)
Gpt2Alanine aminotransferase 2. (470 aa)
CgPICR_015813Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial. (399 aa)
Bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (338 aa)
SdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (223 aa)
SdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (653 aa)
I79_022787NADP-dependent malic enzyme, mitochondrial. (234 aa)
Idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
I79_023874Pyruvate kinase; Belongs to the pyruvate kinase family. (233 aa)
I79_0242312-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase). (220 aa)
I79_025699Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial. (150 aa)
AclyATP-citrate synthase. (59 aa)
I79_026075Isocitrate dehydrogenase [NADP], mitochondrial. (123 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.