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I79_000303 I79_000303 Suclg2 Suclg2 I79_001790 I79_001790 Pdhx Pdhx Dlat Dlat PDH-A1 PDH-A1 I79_006148 I79_006148 H671_1g1921 H671_1g1921 I79_009378 I79_009378 Dlst Dlst I79_009945 I79_009945 Ilvbl Ilvbl Ogdh Ogdh SUCLG1 SUCLG1 I79_013121 I79_013121 Cs Cs Sdhc Sdhc I79_014552 I79_014552 Sucla2 Sucla2 Bcat2 Bcat2 I79_016905 I79_016905 I79_016906 I79_016906 I79_016907 I79_016907 Dld Dld Bckdha Bckdha Sdhb Sdhb Aco2 Aco2 I79_024231 I79_024231 I79_025699 I79_025699 Acly Acly
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000303Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (385 aa)
Suclg2Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial. (358 aa)
I79_001790Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial. (494 aa)
PdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
DlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (646 aa)
PDH-A1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
I79_0061482-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (221 aa)
H671_1g1921Dihydrolipoyl dehydrogenase, mitochondrial. (180 aa)
I79_009378ATP-binding cassette sub-family G member 3. (620 aa)
DlstDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (308 aa)
I79_009945Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial. (123 aa)
IlvblAcetolactate synthase-like protein; Belongs to the TPP enzyme family. (632 aa)
Ogdh2-oxoglutarate dehydrogenase E1 component, mitochondrial. (917 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (333 aa)
I79_013121Thioredoxin reductase 1, cytoplasmic; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (565 aa)
CsCitrate synthase; Belongs to the citrate synthase family. (313 aa)
SdhcSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (132 aa)
I79_014552Isocitrate dehydrogenase [NADP] cytoplasmic. (112 aa)
Sucla2Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial. (238 aa)
Bcat2Branched-chain-amino-acid aminotransferase, mitochondrial. (783 aa)
I79_016905annotation not available (116 aa)
I79_016906annotation not available (61 aa)
I79_016907annotation not available (117 aa)
DldDihydrolipoyl dehydrogenase. (509 aa)
Bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (338 aa)
SdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (223 aa)
Aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
I79_0242312-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase). (220 aa)
I79_025699Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial. (150 aa)
AclyATP-citrate synthase. (59 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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