89 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Selenok	Selenoprotein K. (91 aa)
	I79_001728	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (473 aa)
	Sephs1	Selenide, water dikinase 1. (392 aa)
	Gpx7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
	Prdx1	Peroxiredoxin-1. (199 aa)
	Cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
	Msra	Peptide methionine sulfoxide reductase. (122 aa)
	Nfe2l2	Nuclear factor erythroid 2-related factor 2. (588 aa)
	Txnip	Thioredoxin-interacting protein. (229 aa)
	I79_005447	Glutathione peroxidase 3. (50 aa)
	Gpx3	Glutathione peroxidase 3. (53 aa)
	Msrb2	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (175 aa)
	CgPICR_018709	MIEN1. (115 aa)
	Gsr	Glutathione reductase, mitochondrial. (410 aa)
	Keap1	Kelch-like ECH-associated protein 1. (624 aa)
	Glrx	Glutaredoxin-1. (106 aa)
	Prdx3	Thioredoxin-dependent peroxide reductase, mitochondrial. (257 aa)
	Gpx1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	Mgst1	Microsomal glutathione S-transferase 1. (155 aa)
	I79_007315	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (226 aa)
	Ggt7	Gamma-glutamyltransferase 7. (433 aa)
	Gss	Glutathione synthetase. (474 aa)
	I79_008148	Glutathione peroxidase 2. (151 aa)
	Prdx2	Peroxiredoxin-2. (198 aa)
	Txnrd2	Thioredoxin reductase 2, mitochondrial. (276 aa)
	I79_009034	Thioredoxin reductase 2, mitochondrial. (116 aa)
	I79_009122	Thioredoxin domain-containing protein 6. (237 aa)
	I79_009215	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (199 aa)
	Chac2	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (178 aa)
	I79_009560	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (58 aa)
	Selenot	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa)
	I79_009940	Glutathione S-transferase A1; Belongs to the GST superfamily. (223 aa)
	Secisbp2	Selenocysteine insertion sequence-binding protein 2. (855 aa)
	Gclc	Glutamate--cysteine ligase catalytic subunit. (584 aa)
	I79_010786	Uncharacterized protein. (373 aa)
	Ggct	Gamma-glutamylcyclotransferase. (190 aa)
	Cryz	Quinone oxidoreductase. (327 aa)
	Gstk1	Glutathione S-transferase kappa 1. (111 aa)
	Mgst3	Microsomal glutathione S-transferase 3. (152 aa)
	Gpx6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
	Gpx5	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (192 aa)
	Erp44	Endoplasmic reticulum resident protein ERp44. (258 aa)
	CgPICR_001850	Selenoprotein H. (100 aa)
	Tstd1	Putative thiosulfate sulfurtransferase KAT. (133 aa)
	Glrx2	Glutaredoxin-2, mitochondrial. (83 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	Oplah	5-oxoprolinase. (561 aa)
	CgPICR_015959	Glutathione S-transferase theta-1; Belongs to the GST superfamily. (241 aa)
	I79_015930	Glutathione S-transferase theta-1; Belongs to the GST superfamily. (240 aa)
	I79_015931	Glutathione S-transferase theta-4; Belongs to the GST superfamily. (240 aa)
	I79_015932	Glutathione S-transferase theta-2. (244 aa)
	Ggt1	Gamma-glutamyltranspeptidase 1. (599 aa)
	I79_016330	Thioredoxin domain-containing protein 2. (553 aa)
	I79_016407	Arrestin domain-containing protein 3. (98 aa)
	I79_017016	Epoxide hydrolase 1. (244 aa)
	Ephx1	Epoxide hydrolase 1. (217 aa)
	Selenow	Selenoprotein W. (73 aa)
	I79_017430	Selenoprotein M. (95 aa)
	Scly	Selenocysteine lyase. (392 aa)
	I79_017540	Selenoprotein K. (100 aa)
	Selenoo	Selenoprotein O. (533 aa)
	Gstp1	Glutathione S-transferase P. (221 aa)
	I79_018158	Glutathione S-transferase P 2. (210 aa)
	I79_018719	Glutathione S-transferase A4; Belongs to the GST superfamily. (222 aa)
	Selenon	Selenoprotein N. (343 aa)
	Sepsecs	O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (413 aa)
	Prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (213 aa)
	Srxn1	Sulfiredoxin. (155 aa)
	Gpx8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	I79_021045	Heme oxygenase 1. (81 aa)
	Chac1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa)
	I79_022036	Peroxiredoxin-2. (108 aa)
	Park7	Protein DJ-1. (189 aa)
	I79_022517	Glutathione S-transferase alpha-5. (128 aa)
	I79_022518	Glutathione S-transferase alpha-3. (128 aa)
	I79_022519	Glutathione S-transferase A6; Belongs to the GST superfamily. (242 aa)
	Selenof	15 kDa selenoprotein. (126 aa)
	I79_022778	Glutamate--cysteine ligase regulatory subunit. (225 aa)
	CgPICR_009695	Cytochrome P450 2E1; Belongs to the cytochrome P450 family. (493 aa)
	I79_024324	Glutathione S-transferase Mu 6; Belongs to the GST superfamily. (740 aa)
	I79_024436	Glutathione S-transferase omega-2. (163 aa)
	Sephs2	Selenide, water dikinase 2. (338 aa)
	Gstm3	Glutathione S-transferase. (227 aa)
	I79_024716	Glutathione S-transferase. (265 aa)
	I79_024718	Glutathione S-transferase. (218 aa)
	Anpep	Aminopeptidase N. (325 aa)
	Txn2	Thioredoxin, mitochondrial. (64 aa)
	I79_025475	Uncharacterized protein. (168 aa)
	I79_025478	Glutathione S-transferase Mu 1. (218 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Anpep	Chac1	G3ILR8	G3ICK5	Aminopeptidase N.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.900
Anpep	Chac2	G3ILR8	G3HFL4	Aminopeptidase N.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.901
Anpep	Gclc	G3ILR8	G3HIY9	Aminopeptidase N.	Glutamate--cysteine ligase catalytic subunit.	0.926
Anpep	Ggct	G3ILR8	G3HJM5	Aminopeptidase N.	Gamma-glutamylcyclotransferase.	0.900
Anpep	Ggt1	G3ILR8	G3HY25	Aminopeptidase N.	Gamma-glutamyltranspeptidase 1.	0.926
Anpep	Ggt7	G3ILR8	G3HAP5	Aminopeptidase N.	Gamma-glutamyltransferase 7.	0.926
Anpep	Gss	G3ILR8	G3HAP7	Aminopeptidase N.	Glutathione synthetase.	0.917
Cat	Gclc	G3GYY6	G3HIY9	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutamate--cysteine ligase catalytic subunit.	0.651
Cat	Ggt1	G3GYY6	G3HY25	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Gamma-glutamyltranspeptidase 1.	0.423
Cat	Ggt7	G3GYY6	G3HAP5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Gamma-glutamyltransferase 7.	0.423
Cat	Glrx	G3GYY6	G3H756	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutaredoxin-1.	0.530
Cat	Glrx2	G3GYY6	G3HUN6	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutaredoxin-2, mitochondrial.	0.530
Cat	Gpx1	G3GYY6	G3H8G0	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx3	G3GYY6	G3H573	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase 3.	0.469
Cat	Gpx5	G3GYY6	G3HPX8	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx6	G3GYY6	G3HPX7	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.469
Cat	Gpx7	G3GYY6	G3GW03	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.591
Cat	Gpx8	G3GYY6	G3IAX4	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.591
Cat	Gsr	G3GYY6	G3H609	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione reductase, mitochondrial.	0.738
Cat	Gss	G3GYY6	G3HAP7	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Glutathione synthetase.	0.644