(17 nodes) Mixed, incl. LDLR class B repeat, and Transferrin network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_001239	Low-density lipoprotein receptor-related protein 2. (4664 aa)
	Lrpap1	Alpha-2-macroglobulin receptor-associated protein. (351 aa)
	Gpr6	G-protein coupled receptor 6; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	I79_003225	Serotransferrin. (1227 aa)
	I79_003637	Low-density lipoprotein receptor-related protein 4. (766 aa)
	I79_009834	Disabled-like 2. (705 aa)
	Lpo	Lactoperoxidase. (226 aa)
	Clu	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (447 aa)
	Slc22a17	Solute carrier family 22 member 17. (252 aa)
	Ltf	Lactotransferrin; Belongs to the transferrin family. (648 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	Ankra2	Ankyrin repeat family A protein 2. (97 aa)
	Mesd	LDLR chaperone MESD. (226 aa)
	I79_020923	Low-density lipoprotein receptor-related protein 1B. (254 aa)
	Lcn2	Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
	I79_022918	Low-density lipoprotein receptor-related protein 1B. (274 aa)
	I79_024722	Low-density lipoprotein receptor-related protein 1B. (148 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ankra2	I79_001239	G3I0G2	G3GU85	Ankyrin repeat family A protein 2.	Low-density lipoprotein receptor-related protein 2.	0.881
Ankra2	I79_003637	G3I0G2	G3H0H9	Ankyrin repeat family A protein 2.	Low-density lipoprotein receptor-related protein 4.	0.881
Clu	I79_001239	G3HNJ3	G3GU85	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Low-density lipoprotein receptor-related protein 2.	0.706
Clu	I79_003225	G3HNJ3	G3GZG6	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Serotransferrin.	0.540
Clu	I79_003637	G3HNJ3	G3H0H9	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Low-density lipoprotein receptor-related protein 4.	0.622
Clu	Lcn2	G3HNJ3	G3IBI7	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family.	0.475
Clu	Ltf	G3HNJ3	G3HTA2	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Lactotransferrin; Belongs to the transferrin family.	0.867
Gpr6	I79_020923	G3GXM3	G3IBA3	G-protein coupled receptor 6; Belongs to the G-protein coupled receptor 1 family.	Low-density lipoprotein receptor-related protein 1B.	0.688
Gpr6	I79_022918	G3GXM3	G3IGK1	G-protein coupled receptor 6; Belongs to the G-protein coupled receptor 1 family.	Low-density lipoprotein receptor-related protein 1B.	0.688
Gpr6	I79_024722	G3GXM3	G3ILF7	G-protein coupled receptor 6; Belongs to the G-protein coupled receptor 1 family.	Low-density lipoprotein receptor-related protein 1B.	0.688
I79_001239	Ankra2	G3GU85	G3I0G2	Low-density lipoprotein receptor-related protein 2.	Ankyrin repeat family A protein 2.	0.881
I79_001239	Clu	G3GU85	G3HNJ3	Low-density lipoprotein receptor-related protein 2.	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	0.706
I79_001239	I79_003225	G3GU85	G3GZG6	Low-density lipoprotein receptor-related protein 2.	Serotransferrin.	0.511
I79_001239	I79_009834	G3GU85	G3HGU3	Low-density lipoprotein receptor-related protein 2.	Disabled-like 2.	0.803
I79_001239	Lcn2	G3GU85	G3IBI7	Low-density lipoprotein receptor-related protein 2.	Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family.	0.558
I79_001239	Lrpap1	G3GU85	G3GWB3	Low-density lipoprotein receptor-related protein 2.	Alpha-2-macroglobulin receptor-associated protein.	0.514
I79_001239	Ltf	G3GU85	G3HTA2	Low-density lipoprotein receptor-related protein 2.	Lactotransferrin; Belongs to the transferrin family.	0.675
I79_003225	Clu	G3GZG6	G3HNJ3	Serotransferrin.	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	0.540
I79_003225	I79_001239	G3GZG6	G3GU85	Serotransferrin.	Low-density lipoprotein receptor-related protein 2.	0.511
I79_003225	I79_003637	G3GZG6	G3H0H9	Serotransferrin.	Low-density lipoprotein receptor-related protein 4.	0.511