(25 nodes) Mixed, incl. Negative regulation of CD4-positive, alpha-beta T cell differentiation, and Transcriptional regulation of granulopoiesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gata3	Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
	Irf8	Interferon regulatory factor 8. (424 aa)
	Bcor	BCL-6 corepressor. (1839 aa)
	Bcl6	B-cell lymphoma 6 protein-like. (707 aa)
	I79_001990	Myb proto-oncogene protein. (650 aa)
	Irf4	Interferon regulatory factor 4. (418 aa)
	CUNH17orf49	B-cell CLL/lymphoma 6 member B protein. (305 aa)
	Rarb	Retinoic acid receptor beta. (284 aa)
	Tbx21	T-box transcription factor TBX21. (365 aa)
	Ets1	Protein C-ets-1. (257 aa)
	I79_006520	Friend leukemia integration 1 transcription factor. (404 aa)
	I79_008077	Uncharacterized protein. (152 aa)
	I79_009672	Potassium voltage-gated channel subfamily H member 6. (945 aa)
	I79_011902	Paired box protein Pax-5. (386 aa)
	Runx3	Runt-related transcription factor 3. (299 aa)
	Foxp3	Forkhead box protein P3. (428 aa)
	Runx1	Runt-related transcription factor 1. (462 aa)
	I79_014884	Transcriptional regulator ERG. (261 aa)
	Prdm1	PR domain zinc finger protein 1. (825 aa)
	Ets2	Protein C-ets-2. (462 aa)
	Spib	Transcription factor Spi-B. (269 aa)
	I79_020948	Interferon regulatory factor 1. (369 aa)
	I79_021155	Paired box protein Pax-2. (503 aa)
	I79_022268	Death-associated protein kinase 1. (184 aa)
	I79_024478	Death-associated protein kinase 1. (157 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcl6	Bcor	G3GT91	G3GSG2	B-cell lymphoma 6 protein-like.	BCL-6 corepressor.	0.953
Bcl6	CUNH17orf49	G3GT91	G3GYA7	B-cell lymphoma 6 protein-like.	B-cell CLL/lymphoma 6 member B protein.	0.631
Bcl6	Foxp3	G3GT91	G3HNB1	B-cell lymphoma 6 protein-like.	Forkhead box protein P3.	0.763
Bcl6	Gata3	G3GT91	G3GR59	B-cell lymphoma 6 protein-like.	Trans-acting T-cell-specific transcription factor GATA-3.	0.454
Bcl6	I79_011902	G3GT91	G3HME2	B-cell lymphoma 6 protein-like.	Paired box protein Pax-5.	0.574
Bcl6	Irf4	G3GT91	G3GWW9	B-cell lymphoma 6 protein-like.	Interferon regulatory factor 4.	0.774
Bcl6	Irf8	G3GT91	G3GRW0	B-cell lymphoma 6 protein-like.	Interferon regulatory factor 8.	0.462
Bcl6	Spib	G3GT91	G3I733	B-cell lymphoma 6 protein-like.	Transcription factor Spi-B.	0.556
Bcl6	Tbx21	G3GT91	G3H5U9	B-cell lymphoma 6 protein-like.	T-box transcription factor TBX21.	0.600
Bcor	Bcl6	G3GSG2	G3GT91	BCL-6 corepressor.	B-cell lymphoma 6 protein-like.	0.953
Bcor	CUNH17orf49	G3GSG2	G3GYA7	BCL-6 corepressor.	B-cell CLL/lymphoma 6 member B protein.	0.805
CUNH17orf49	Bcl6	G3GYA7	G3GT91	B-cell CLL/lymphoma 6 member B protein.	B-cell lymphoma 6 protein-like.	0.631
CUNH17orf49	Bcor	G3GYA7	G3GSG2	B-cell CLL/lymphoma 6 member B protein.	BCL-6 corepressor.	0.805
Ets1	Ets2	G3H823	G3I053	Protein C-ets-1.	Protein C-ets-2.	0.972
Ets1	Gata3	G3H823	G3GR59	Protein C-ets-1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.629
Ets1	I79_008077	G3H823	G3HC73	Protein C-ets-1.	Uncharacterized protein.	0.702
Ets1	I79_011902	G3H823	G3HME2	Protein C-ets-1.	Paired box protein Pax-5.	0.929
Ets1	I79_021155	G3H823	G3IBX2	Protein C-ets-1.	Paired box protein Pax-2.	0.811
Ets1	Runx1	G3H823	G3HNW1	Protein C-ets-1.	Runt-related transcription factor 1.	0.864
Ets1	Runx3	G3H823	G3HMU5	Protein C-ets-1.	Runt-related transcription factor 3.	0.727