STRINGSTRING
Rptor Rptor Foxo3 Foxo3 I79_003621 I79_003621 I79_003714 I79_003714 Akt1 Akt1 Sirt1 Sirt1 Phlpp2 Phlpp2 Rheb Rheb I79_007676 I79_007676 Tsc2 Tsc2 Mlst8 Mlst8 I79_008249 I79_008249 Phlpp1 Phlpp1 I79_009837 I79_009837 Rps6kb1 Rps6kb1 Akt2 Akt2 Crybb3 Crybb3 Akt3 Akt3 Foxo1 Foxo1 Gsk3a Gsk3a I79_017572 I79_017572 Rps6kb2 Rps6kb2 Akt1s1 Akt1s1 Foxo4 Foxo4 Mapkap1 Mapkap1 Trib3 Trib3 Arhgap8 Arhgap8 I79_021319 I79_021319 Mtor Mtor I79_022199 I79_022199 Stk32c Stk32c Eif4b Eif4b Prmt1 Prmt1 I79_025249 I79_025249
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RptorRegulatory-associated protein of mTOR. (1331 aa)
Foxo3Forkhead box protein O3. (672 aa)
I79_003621TBC1 domain family member 7. (332 aa)
I79_00371440S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Phlpp2PH domain leucine-rich repeat-containing protein phosphatase 2. (1322 aa)
RhebGTP-binding protein Rheb. (179 aa)
I79_007676Gamma-crystallin N; Belongs to the beta/gamma-crystallin family. (194 aa)
Tsc2Tuberin. (1546 aa)
Mlst8Target of rapamycin complex subunit LST8. (326 aa)
I79_008249Forkhead box protein O6. (270 aa)
Phlpp1PH domain leucine-rich repeat protein phosphatase 1. (1303 aa)
I79_009837Rapamycin-insensitive companion of mTOR. (1308 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Crybb3Uncharacterized protein KIAA1671; Belongs to the beta/gamma-crystallin family. (1903 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Foxo1Forkhead box protein O1. (469 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
I79_017572Target of rapamycin complex 2 subunit MAPKAP1. (140 aa)
Rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
Akt1s1Proline-rich AKT1 substrate 1. (252 aa)
Foxo4Forkhead box protein O4. (506 aa)
Mapkap1Target of rapamycin complex 2 subunit MAPKAP1. (316 aa)
Trib3Tribbles-like 3. (353 aa)
Arhgap8Rho GTPase-activating protein 8. (89 aa)
I79_02131914-3-3 protein theta; Belongs to the 14-3-3 family. (191 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_022199Hamartin. (966 aa)
Stk32cSerine/threonine-protein kinase 32C. (367 aa)
Eif4bEukaryotic translation initiation factor 4B. (616 aa)
Prmt1Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
I79_02524940S ribosomal protein S6. (121 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.