STRINGSTRING
I79_000157 I79_000157 Plcg2 Plcg2 I79_000473 I79_000473 I79_000474 I79_000474 Tiam1 Tiam1 I79_000883 I79_000883 CgPICR_012052 CgPICR_012052 Ptpn6 Ptpn6 Eml4 Eml4 I79_001734 I79_001734 Hgfac Hgfac Rac3 Rac3 Pik3r5 Pik3r5 I79_002696 I79_002696 I79_002944 I79_002944 Blnk Blnk Dok3 Dok3 I79_003896 I79_003896 I79_004244 I79_004244 Kras Kras I79_005111 I79_005111 Pik3r1 Pik3r1 I79_005331 I79_005331 Fer Fer H671_xg20512 H671_xg20512 Erbb2 Erbb2 Igf1 Igf1 Mst1r Mst1r I79_006732 I79_006732 I79_007063 I79_007063 I79_007089 I79_007089 I79_007090 I79_007090 Shc1 Shc1 Sh3gl1 Sh3gl1 I79_008231 I79_008231 I79_008304 I79_008304 Hck Hck I79_008941 I79_008941 Ptpn1 Ptpn1 I79_009115 I79_009115 I79_009116 I79_009116 Shc2 Shc2 Ripk4 Ripk4 Crkl Crkl I79_009586 I79_009586 I79_009691 I79_009691 Srms Srms Rasgrp1 Rasgrp1 Syk Syk Shc3 Shc3 Igf1r Igf1r Sh3gl2 Sh3gl2 Fyn Fyn Hgf Hgf Nras Nras Cblb Cblb Ikzf4 Ikzf4 Shc4 Shc4 Rras2 Rras2 Grb14 Grb14 Matk Matk Lcp2 Lcp2 Nrg1 Nrg1 I79_014451 I79_014451 I79_014637 I79_014637 I79_014973 I79_014973 Grap2 Grap2 Plcg1 Plcg1 Insr Insr Commd8 Commd8 I79_015659 I79_015659 Ins Ins I79_016223 I79_016223 Frs2 Frs2 Frs3 Frs3 Pik3ca Pik3ca Lyn Lyn Sh3gl3 Sh3gl3 Hras Hras CgPICR_017317 CgPICR_017317 I79_019028 I79_019028 Tgfa Tgfa Rasgrp2 Rasgrp2 Shoc2 Shoc2 Rgl2 Rgl2 I79_019403 I79_019403 Pik3cd Pik3cd Lat Lat Fgr Fgr H671_5g14804 H671_5g14804 Sos2 Sos2 I79_020316 I79_020316 I79_021125 I79_021125 Ereg Ereg Areg Areg Inppl1 Inppl1 I79_021564 I79_021564 Irs1 Irs1 I79_022271 I79_022271 I79_022484 I79_022484 Yes1 Yes1 Tec Tec Rras Rras Csk Csk I79_023594 I79_023594 I79_023828 I79_023828 Inpp5d Inpp5d Irs2 Irs2 Vav2 Vav2 I79_024372 I79_024372 Sh3glb2 Sh3glb2 I79_025534 I79_025534
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000157E3 ubiquitin-protein ligase NEDD4. (1032 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
I79_000473Transmembrane protein 110. (204 aa)
I79_000474Transmembrane protein 110. (86 aa)
Tiam1T-lymphoma invasion and metastasis-inducing protein 1. (1591 aa)
I79_000883Ras-specific guanine nucleotide-releasing factor 1; Belongs to the peptidase C1 family. (1632 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
Ptpn6Tyrosine-protein phosphatase non-receptor type 6. (592 aa)
Eml4Echinoderm microtubule-associated protein-like 4. (983 aa)
I79_001734GRB2-related adapter protein. (123 aa)
HgfacHepatocyte growth factor activator. (658 aa)
Rac3Ras-related C3 botulinum toxin substrate 3. (148 aa)
Pik3r5Phosphoinositide 3-kinase regulatory subunit 5. (148 aa)
I79_002696Phosphoinositide 3-kinase regulatory subunit 6. (395 aa)
I79_002944Phosphatidylinositol 3-kinase regulatory subunit gamma. (460 aa)
BlnkB-cell linker protein. (457 aa)
Dok3Docking protein 3. (182 aa)
I79_003896Coagulation factor XII; Belongs to the peptidase S1 family. (560 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
KrasGTPase KRas. (155 aa)
I79_005111Phosphatidylinositol 3-kinase regulatory subunit beta. (653 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
I79_005331Receptor tyrosine-protein kinase erbB-4. (480 aa)
FerTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
H671_xg20512SH3 domain-containing kinase-binding protein 1. (602 aa)
Erbb2Receptor protein-tyrosine kinase. (1256 aa)
Igf1Insulin-like growth factor I. (75 aa)
Mst1rMacrophage-stimulating protein receptor. (1382 aa)
I79_006732KH domain-containing, RNA-binding, signal transduction-associated protein 1. (195 aa)
I79_007063Hepatocyte growth factor receptor. (1222 aa)
I79_007089Receptor tyrosine-protein kinase erbB-4. (225 aa)
I79_007090Receptor tyrosine-protein kinase erbB-4. (182 aa)
Shc1SHC-transforming protein 1. (579 aa)
Sh3gl1Endophilin-A2. (368 aa)
I79_008231Proto-oncogene vav. (879 aa)
I79_008304Platelet endothelial cell adhesion molecule. (596 aa)
HckTyrosine-protein kinase. (503 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Ptpn1Tyrosine-protein phosphatase non-receptor type 1. (335 aa)
I79_009115Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (441 aa)
I79_009116Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (311 aa)
Shc2SHC-transforming protein 2. (570 aa)
Ripk4Receptor-interacting serine/threonine-protein kinase 4. (723 aa)
CrklCrk-like protein. (303 aa)
I79_009586Tyrosine-protein kinase receptor. (1183 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
SrmsTyrosine-protein kinase. (507 aa)
Rasgrp1RAS guanyl-releasing protein 1. (787 aa)
SykTyrosine-protein kinase. (611 aa)
Shc3SHC-transforming protein 3. (486 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
Sh3gl2Endophilin-A1. (152 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
NrasCold shock domain-containing protein E1. (451 aa)
CblbE3 ubiquitin-protein ligase CBL-B. (984 aa)
Ikzf4Receptor protein-tyrosine kinase. (1902 aa)
Shc4SHC-transforming protein 4. (228 aa)
Rras2Ras-related protein R-Ras2. (154 aa)
Grb14Growth factor receptor-bound protein 14. (466 aa)
MatkTyrosine-protein kinase. (545 aa)
Lcp2Lymphocyte cytosolic protein 2. (241 aa)
Nrg1Pro-neuregulin-1, membrane-bound isoform. (259 aa)
I79_014451Pro-neuregulin-1, membrane-bound isoform. (639 aa)
I79_014637Muscle M-line assembly protein unc-89. (338 aa)
I79_014973Pro-neuregulin-2, membrane-bound isoform. (386 aa)
Grap2GRB2-related adaptor protein 2. (324 aa)
Plcg1Phosphoinositide phospholipase C. (1217 aa)
InsrInsulin receptor. (114 aa)
Commd8Atrial natriuretic peptide-converting enzyme. (632 aa)
I79_015659Tyrosine-protein phosphatase non-receptor type 18. (187 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
I79_016223Tyrosine-protein kinase-like 7. (98 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
Frs3Fibroblast growth factor receptor substrate 3. (492 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
LynTyrosine-protein kinase. (289 aa)
Sh3gl3Endophilin-A3. (274 aa)
HrasGTPase HRas-like protein. (189 aa)
CgPICR_017317Insulin receptor substrate 1. (493 aa)
I79_019028Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (437 aa)
TgfaProtransforming growth factor alpha. (211 aa)
Rasgrp2RAS guanyl-releasing protein 2. (540 aa)
Shoc2Leucine-rich repeat protein SHOC-2. (582 aa)
Rgl2Ral guanine nucleotide dissociation stimulator-like 2. (338 aa)
I79_019403Ras-specific guanine nucleotide-releasing factor 2. (287 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (910 aa)
LatLinker for activation of T-cells family member 1. (243 aa)
FgrTyrosine-protein kinase. (435 aa)
H671_5g14804Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1012 aa)
Sos2Son of sevenless-like 2. (166 aa)
I79_020316Guanine nucleotide exchange factor VAV3. (604 aa)
I79_021125Epigen. (135 aa)
EregProepiregulin. (162 aa)
AregAmphiregulin. (230 aa)
Inppl1Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1253 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
I79_022484Rap guanine nucleotide exchange factor 1. (934 aa)
Yes1Tyrosine-protein kinase. (541 aa)
TecTyrosine-protein kinase. (500 aa)
RrasRas-related protein R-Ras. (126 aa)
CskTyrosine-protein kinase. (450 aa)
I79_023594Atrial natriuretic peptide-converting enzyme. (271 aa)
I79_023828Ras-specific guanine nucleotide-releasing factor 2. (584 aa)
Inpp5dPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (91 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Vav2Guanine nucleotide exchange factor VAV2. (453 aa)
I79_024372Guanine nucleotide exchange factor VAV2. (233 aa)
Sh3glb2Endophilin-B2. (125 aa)
I79_025534Hyaluronan-binding protein 2. (234 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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