STRINGSTRING
Fgf23 Fgf23 I79_001364 I79_001364 Fgf17 Fgf17 I79_002099 I79_002099 Fgf20 Fgf20 I79_003906 I79_003906 I79_004031 I79_004031 I79_006679 I79_006679 Nrp2 Nrp2 Fgfrl1 Fgfrl1 Fgf1 Fgf1 Fgf22 Fgf22 Pgf Pgf Vegfc Vegfc I79_009992 I79_009992 Kitlg Kitlg Fgfr3 Fgfr3 Kl Kl Fgf16 Fgf16 I79_012556 I79_012556 I79_013660 I79_013660 Pdgfrb Pdgfrb Pdgfa Pdgfa Npm3 Npm3 Pdgfd Pdgfd Fgf21 Fgf21 H671_1g1070 H671_1g1070 Pdgfb Pdgfb Fgf3 Fgf3 Fgf4 Fgf4 Fgf19 Fgf19 I79_019149 I79_019149 Vegfb Vegfb Fgf7 Fgf7 I79_020968 I79_020968 I79_020969 I79_020969 I79_022034 I79_022034 Fgfr2 Fgfr2 Pdgfra Pdgfra Klb Klb Fgfbp1 Fgfbp1 Kit Kit
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
I79_003906Fibroblast growth factor receptor 4. (1040 aa)
I79_004031Fibroblast growth factor receptor. (731 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Nrp2Neuropilin; Belongs to the neuropilin family. (909 aa)
Fgfrl1Fibroblast growth factor receptor-like 1. (503 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fgf22Fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (70 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
I79_009992Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (259 aa)
KitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
KlKlotho. (900 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
I79_012556Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1227 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
PdgfaPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (265 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
PdgfdPlatelet-derived growth factor D. (253 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
H671_1g1070Fibroblast growth factor 5-like protein; Belongs to the heparin-binding growth factors family. (239 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_020969Fibroblast growth factor 18. (85 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
KlbBeta-klotho; Belongs to the glycosyl hydrolase 1 family. (730 aa)
Fgfbp1Fibroblast growth factor-binding protein 1. (248 aa)
KitMast/stem cell growth factor receptor. (452 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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