(12 nodes) TRAF6-mediated induction of TAK1 complex within TLR4 complex, and TIR domain binding network (Cricetulus griseus)

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Your Input:
	I79_000697	Mitogen-activated protein kinase kinase kinase 7. (287 aa)
	Irak2	Interleukin-1 receptor-associated kinase-like 2. (626 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
	Tab2	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2. (693 aa)
	Ticam1	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (699 aa)
	Myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
	Irak1	Interleukin-1 receptor-associated kinase 1. (494 aa)
	Ticam2	TIR domain-containing adapter molecule 2. (233 aa)
	Tab3	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3. (715 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Tab1	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1. (336 aa)
	Irak4	Interleukin-1 receptor-associated kinase 4. (462 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I79_000697	Irak1	G3GSS8	G3HSV4	Mitogen-activated protein kinase kinase kinase 7.	Interleukin-1 receptor-associated kinase 1.	0.767
I79_000697	Irak2	G3GSS8	G3GX41	Mitogen-activated protein kinase kinase kinase 7.	Interleukin-1 receptor-associated kinase-like 2.	0.692
I79_000697	Myd88	G3GSS8	G3HQV3	Mitogen-activated protein kinase kinase kinase 7.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.968
I79_000697	Tab1	G3GSS8	G3I2I7	Mitogen-activated protein kinase kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1.	0.969
I79_000697	Tab2	G3GSS8	G3H3T2	Mitogen-activated protein kinase kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2.	0.993
I79_000697	Tab3	G3GSS8	G3HXG0	Mitogen-activated protein kinase kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3.	0.984
I79_000697	Ticam1	G3GSS8	G3HCH9	Mitogen-activated protein kinase kinase kinase 7.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.809
I79_000697	Ticam2	G3GSS8	G3HTM6	Mitogen-activated protein kinase kinase kinase 7.	TIR domain-containing adapter molecule 2.	0.938
I79_000697	Tlr4	G3GSS8	G3I192	Mitogen-activated protein kinase kinase kinase 7.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.951
I79_000697	Traf6	G3GSS8	G3GZ05	Mitogen-activated protein kinase kinase kinase 7.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.993
Irak1	I79_000697	G3HSV4	G3GSS8	Interleukin-1 receptor-associated kinase 1.	Mitogen-activated protein kinase kinase kinase 7.	0.767
Irak1	Irak2	G3HSV4	G3GX41	Interleukin-1 receptor-associated kinase 1.	Interleukin-1 receptor-associated kinase-like 2.	0.987
Irak1	Irak4	G3HSV4	G3IB29	Interleukin-1 receptor-associated kinase 1.	Interleukin-1 receptor-associated kinase 4.	0.999
Irak1	Myd88	G3HSV4	G3HQV3	Interleukin-1 receptor-associated kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.999
Irak1	Tab1	G3HSV4	G3I2I7	Interleukin-1 receptor-associated kinase 1.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1.	0.974
Irak1	Tab2	G3HSV4	G3H3T2	Interleukin-1 receptor-associated kinase 1.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2.	0.998
Irak1	Tab3	G3HSV4	G3HXG0	Interleukin-1 receptor-associated kinase 1.	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3.	0.983
Irak1	Ticam1	G3HSV4	G3HCH9	Interleukin-1 receptor-associated kinase 1.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.962
Irak1	Ticam2	G3HSV4	G3HTM6	Interleukin-1 receptor-associated kinase 1.	TIR domain-containing adapter molecule 2.	0.648
Irak1	Tlr4	G3HSV4	G3I192	Interleukin-1 receptor-associated kinase 1.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.871