STRINGSTRING
I79_000092 I79_000092 I79_000120 I79_000120 Rnf111 Rnf111 I79_000185 I79_000185 Wnt7a Wnt7a Prickle2 Prickle2 Bmp2 Bmp2 Rgma Rgma I79_000688 I79_000688 Nlk Nlk Ogfrl1 Ogfrl1 Wnt5a Wnt5a Sftpc Sftpc Sfrp4 Sfrp4 Tgfbr2 Tgfbr2 Zfyve9 Zfyve9 Rnf6 Rnf6 Notum Notum Phf23 Phf23 Bmpr2 Bmpr2 Fzd7 Fzd7 Ror1 Ror1 I79_003394 I79_003394 Sfrp5 Sfrp5 Fzd3 Fzd3 Nog Nog Tcf7 Tcf7 I79_005100 I79_005100 Lgr5 Lgr5 I79_005573 I79_005573 Nkd1 Nkd1 Grem2 Grem2 Nodal Nodal I79_006254 I79_006254 Tgfbr1 Tgfbr1 Dkk1 Dkk1 Vangl2 Vangl2 Axin2 Axin2 Wnt5b Wnt5b I79_006745 I79_006745 Smad6 Smad6 Smad3 Smad3 Smad1 Smad1 Wnt2 Wnt2 Fzd9 Fzd9 Smad2 Smad2 Gsk3b Gsk3b I79_007514 I79_007514 I79_007641 I79_007641 Lrp6 Lrp6 Bmp7 Bmp7 Axin1 Axin1 Cer1 Cer1 I79_008298 I79_008298 I79_008405 I79_008405 Bmp6 Bmp6 I79_008571 I79_008571 Fst Fst Rspo1 Rspo1 Tgfbr3 Tgfbr3 I79_008996 I79_008996 I79_009100 I79_009100 Wnt8a Wnt8a Apc Apc Apc2 Apc2 Tgfb3 Tgfb3 Smad9 Smad9 Sfrp1 Sfrp1 I79_010136 I79_010136 Acvr1 Acvr1 I79_010194 I79_010194 I79_010224 I79_010224 Skil Skil Bmp10 Bmp10 Wnt4 Wnt4 Smad5 Smad5 I79_010796 I79_010796 Msantd3 Msantd3 I79_011268 I79_011268 Fzd1 Fzd1 Sost Sost Fzd2 Fzd2 I79_012253 I79_012253 Prickle3 Prickle3 Porcn Porcn Rgmb Rgmb I79_012501 I79_012501 I79_012512 I79_012512 Tcf7l1 Tcf7l1 Smad7 Smad7 Acvr2b Acvr2b Gdf11 Gdf11 I79_013844 I79_013844 Bambi Bambi I79_014060 I79_014060 Tdgf1 Tdgf1 I79_014214 I79_014214 Smad4 Smad4 Nbl1 Nbl1 Fzd5 Fzd5 Wnt11 Wnt11 Amhr2 Amhr2 CgPICR_010134 CgPICR_010134 I79_014841 I79_014841 Inhba Inhba Tspan12 Tspan12 Inhbc Inhbc Inhbe Inhbe I79_015320 I79_015320 I79_015321 I79_015321 Foxh1 Foxh1 Wls Wls Zfyve16 Zfyve16 Fam151b Fam151b Ankrd34b Ankrd34b Acvr2a Acvr2a Smurf1 Smurf1 I79_016286 I79_016286 Twsg1 Twsg1 Wnt8b Wnt8b Tmem174 Tmem174 I79_017052 I79_017052 Prickle4 Prickle4 Fzd10 Fzd10 Gdf3 Gdf3 Ski Ski Erfe Erfe I79_017541 I79_017541 H671_4g11668 H671_4g11668 Dvl3 Dvl3 I79_017833 I79_017833 Dvl1 Dvl1 I79_018312 I79_018312 Ndp Ndp Lrp5 Lrp5 Lgr4 Lgr4 Wnt1 Wnt1 Wnt10b Wnt10b I79_019398 I79_019398 Lmbr1 Lmbr1 I79_020072 I79_020072 I79_020073 I79_020073 Tgfb1 Tgfb1 I79_020783 I79_020783 CUNH14orf28 CUNH14orf28 Sox18 Sox18 Acvrl1 Acvrl1 Wnt7b Wnt7b Grem1 Grem1 I79_021718 I79_021718 Hecw2 Hecw2 Wnt16 Wnt16 I79_021938 I79_021938 I79_022080 I79_022080 Fzd4 Fzd4 Celsr1 Celsr1 Kremen2 Kremen2 I79_022479 I79_022479 Prickle1 Prickle1 I79_022562 I79_022562 I79_022994 I79_022994 I79_023010 I79_023010 Wnt2b Wnt2b I79_023430 I79_023430 Tcf7l2 Tcf7l2 I79_023738 I79_023738 Dkk2 Dkk2 I79_023775 I79_023775 Bmp3 Bmp3 Mstn Mstn I79_024337 I79_024337 Ctnnbip1 Ctnnbip1 I79_024810 I79_024810 I79_024959 I79_024959 I79_025040 I79_025040 Nkd2 Nkd2 I79_025316 I79_025316 I79_025356 I79_025356 I79_025459 I79_025459 I79_025513 I79_025513 Acvr1b Acvr1b I79_025618 I79_025618 I79_025627 I79_025627 Wnt9b Wnt9b I79_025783 I79_025783 Rspo3 Rspo3 I79_026084 I79_026084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
Rnf111E3 ubiquitin-protein ligase Arkadia. (990 aa)
I79_000185BCL2/adenovirus E1B 19 kDa protein-interacting protein 2. (274 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
Prickle2Prickle-like protein 2. (845 aa)
Bmp2Bone morphogenetic protein 2. (272 aa)
RgmaRepulsive guidance molecule A. (414 aa)
I79_000688Ankyrin repeat domain-containing protein 6. (498 aa)
NlkSerine/threonine protein kinase NLK. (410 aa)
Ogfrl1Opioid growth factor receptor-like protein 1. (374 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
SftpcMetalloendopeptidase. (1019 aa)
Sfrp4Secreted frizzled-related protein 4. (348 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Zfyve9Zinc finger FYVE domain-containing protein. (1413 aa)
Rnf6E3 ubiquitin-protein ligase. (666 aa)
NotumProtein notum-like. (354 aa)
Phf23Segment polarity protein dishevelled-like DVL-2. (697 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Fzd7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (438 aa)
Ror1Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (874 aa)
I79_003394Metalloendopeptidase. (995 aa)
Sfrp5Secreted frizzled-related protein 5. (247 aa)
Fzd3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
NogNoggin. (117 aa)
Tcf7Transcription factor 7. (213 aa)
I79_005100Growth/differentiation factor 15. (96 aa)
Lgr5Leucine-rich repeat-containing G-protein coupled receptor 5. (555 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Nkd1Protein naked cuticle-like 1. (425 aa)
Grem2Gremlin. (168 aa)
NodalNodal. (309 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
Dkk1Dickkopf-related protein 1. (269 aa)
Vangl2Vang-like protein. (521 aa)
Axin2Axin-2. (809 aa)
Wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Smad1Mothers against decapentaplegic-like 1. (232 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (439 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
I79_007514Growth/differentiation factor 5. (253 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Axin1Axin-1. (863 aa)
Cer1Cerberus. (272 aa)
I79_008298E3 ubiquitin-protein ligase SMURF2. (571 aa)
I79_008405Tyrosine-protein kinase RYK. (141 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
I79_008571UPF0554 protein C2orf43-like. (354 aa)
FstFollistatin. (316 aa)
Rspo1R-spondin-1. (262 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
I79_008996Opioid growth factor receptor. (442 aa)
I79_009100Latent-transforming growth factor beta-binding protein 1. (1194 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (195 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Apc2Adenomatous polyposis coli protein 2. (2236 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Smad9Mothers against decapentaplegic homolog. (465 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010136Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
I79_010194Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (387 aa)
I79_010224BMP-binding endothelial regulator protein. (371 aa)
SkilSki-like protein. (677 aa)
Bmp10Bone morphogenetic protein 10. (399 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Smad5Mothers against decapentaplegic homolog. (462 aa)
I79_010796Vang-like protein. (526 aa)
Msantd3Tomoregulin-1. (363 aa)
I79_011268Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3109 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
SostSclerostin. (213 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
I79_012253Prickle-like protein 3. (134 aa)
Prickle3Prickle-like protein 3. (181 aa)
PorcnUncharacterized protein; Belongs to the membrane-bound acyltransferase family. (229 aa)
RgmbRGM domain family member B-like protein. (250 aa)
I79_012501Zinc/RING finger protein 3. (672 aa)
I79_012512Neurofilament heavy polypeptide; Belongs to the intermediate filament family. (833 aa)
Tcf7l1Transcription factor 7-like 1. (297 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (559 aa)
Gdf11Growth/differentiation factor 11. (268 aa)
I79_013844Caytaxin. (355 aa)
BambiBMP and activin membrane-bound inhibitor-like. (218 aa)
I79_014060Meprin A subunit beta. (298 aa)
Tdgf1Receptor-transporting protein 3. (313 aa)
I79_014214Meprin A subunit. (706 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Nbl1Neuroblastoma suppressor of tumorigenicity 1-like protein. (178 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (616 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Amhr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (57 aa)
CgPICR_010134Left-right determination factor. (365 aa)
I79_014841Left-right determination factor. (368 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
Tspan12Tetraspanin-12. (68 aa)
InhbcInhibin beta C chain. (352 aa)
InhbeInhibin beta E chain. (350 aa)
I79_015320Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (477 aa)
I79_015321Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
Foxh1Forkhead box protein H1. (367 aa)
WlsIntegral membrane protein GPR177. (166 aa)
Zfyve16Zinc finger FYVE domain-containing protein. (1523 aa)
Fam151bProtein FAM151B. (272 aa)
Ankrd34bAnkyrin repeat domain-containing protein 34B. (510 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
Smurf1E3 ubiquitin-protein ligase SMURF1. (303 aa)
I79_016286Carcinoembryonic antigen-related cell adhesion molecule 1. (334 aa)
Twsg1Twisted gastrulation protein-like 1. (222 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
Tmem174Transmembrane protein 174. (243 aa)
I79_017052Prickle-like protein 4. (300 aa)
Prickle4Prickle-like protein 4. (219 aa)
Fzd10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa)
Gdf3Growth/differentiation factor 3. (361 aa)
SkiSki oncogene. (636 aa)
ErfeProtein FAM132B. (344 aa)
I79_017541Uridine-cytidine kinase 1. (178 aa)
H671_4g11668Chordin. (842 aa)
Dvl3Segment polarity protein dishevelled-like DVL-3. (503 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Dvl1Putative segment polarity protein dishevelledVL-1-like protein. (695 aa)
I79_018312Tyrosine-protein kinase RYK. (163 aa)
NdpNorrin. (113 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
I79_019398Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2335 aa)
Lmbr1Limb region 1 protein. (165 aa)
I79_020072Latent-transforming growth factor beta-binding protein 2. (52 aa)
I79_020073Latent-transforming growth factor beta-binding protein 2. (286 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
CUNH14orf28GM527. (310 aa)
Sox18Transcription factor SOX-18. (377 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Grem1Gremlin-1. (117 aa)
I79_021718Low-density lipoprotein receptor-related protein 10. (264 aa)
Hecw2E3 ubiquitin-protein ligase HECW2. (85 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
I79_021938Mothers against decapentaplegic-like 1. (122 aa)
I79_022080Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (402 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
Celsr1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1009 aa)
Kremen2Kremen protein 2. (87 aa)
I79_022479E3 ubiquitin-protein ligase RLIM. (767 aa)
Prickle1Prickle-like protein 1. (619 aa)
I79_022562Tripeptidyl-peptidase 2. (56 aa)
I79_022994Dapper-like 1. (530 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (536 aa)
I79_023430GSK-3-binding protein FRAT2. (109 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
I79_023738Cadherin EGF LAG seven-pass G-type receptor 1. (979 aa)
Dkk2Dickkopf-related protein 2. (149 aa)
I79_023775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (256 aa)
Bmp3Bone morphogenetic protein 3. (487 aa)
MstnGrowth/differentiation factor 8. (295 aa)
I79_024337Opioid growth factor receptor. (176 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_024810Cryptic protein. (69 aa)
I79_024959Mothers against decapentaplegic-like 1. (161 aa)
I79_025040GSK-3-binding protein FRAT2. (121 aa)
Nkd2Protein naked cuticle-like 2. (417 aa)
I79_025316Mothers against decapentaplegic-like 1. (104 aa)
I79_025356Carcinoembryonic antigen-related cell adhesion molecule 1. (117 aa)
I79_025459Mothers against decapentaplegic-like 1. (117 aa)
I79_025513Mothers against decapentaplegic-like 1. (151 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
I79_025618Proto-oncogene FRAT1. (114 aa)
I79_025627Proto-oncogene FRAT1. (240 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
I79_025783Mothers against decapentaplegic-like 1. (97 aa)
Rspo3R-spondin-3. (81 aa)
I79_026084GSK3-beta interaction protein. (80 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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