27 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Gxylt2	Glycosyltransferase 8 domain-containing protein 4. (539 aa)
	Jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
	Lfng	Beta-1,3-N-acetylglucosaminyltransferase. (378 aa)
	Fut11	Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (524 aa)
	Rfng	Beta-1,3-N-acetylglucosaminyltransferase radical fringe. (229 aa)
	I79_004721	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
	Maml2	Mastermind-like protein 2. (914 aa)
	Pofut2	GDP-fucose protein O-fucosyltransferase 2. (190 aa)
	Maml3	Mastermind-like protein 3. (431 aa)
	Poglut3	KDEL motif-containing protein 2. (452 aa)
	I79_010785	Delta-like protein 3. (388 aa)
	Rbpjl	Recombining binding protein suppressor of hairless-like protein. (515 aa)
	I79_011804	Neurogenic locus notch-like protein 3. (2181 aa)
	Heyl	Hairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	Notch2	Neurogenic locus notch-like protein 2. (1521 aa)
	I79_015033	Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
	Gpsm3	Neurogenic locus notch-like protein 4. (1797 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2527 aa)
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
	Rbpj	Recombining binding protein suppressor of hairless-like protein. (486 aa)
	Dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
	Poglut2	KDEL motif-containing protein 1. (502 aa)
	I79_022037	Xylosyltransferase 1. (332 aa)
	Gxylt1	Glycosyltransferase 8 domain-containing protein 3. (345 aa)
	Mfng	Beta-1,3-N-acetylglucosaminyltransferase manic fringe. (324 aa)
	POFUT1	GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...] (392 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dll1	Dll4	G3HNT7	G3ICK3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.942
Dll1	Gpsm3	G3HNT7	G3HZC0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch-like protein 4.	0.767
Dll1	Gxylt1	G3HNT7	G3IHJ0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Glycosyltransferase 8 domain-containing protein 3.	0.618
Dll1	Gxylt2	G3HNT7	G3GS47	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Glycosyltransferase 8 domain-containing protein 4.	0.620
Dll1	Hey2	G3HNT7	G3IB43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.540
Dll1	Heyl	G3HNT7	G3HN78	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif-like protein.	0.529
Dll1	I79_011804	G3HNT7	G3HM56	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch-like protein 3.	0.888
Dll1	I79_015033	G3HNT7	G3HVP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.560
Dll1	I79_022037	G3HNT7	G3IE93	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Xylosyltransferase 1.	0.416
Dll1	Jag1	G3HNT7	G3GSA7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.577
Dll1	Lfng	G3HNT7	G3GVF0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.714
Dll1	Maml2	G3HNT7	G3H7E1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind-like protein 2.	0.696
Dll1	Maml3	G3HNT7	G3HAT7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind-like protein 3.	0.622
Dll1	Mfng	G3HNT7	G3IJX8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase manic fringe.	0.589
Dll1	NOTCH1	G3HNT7	G3I6Z6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...]	0.995
Dll1	Notch2	G3HNT7	G3HP78	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch-like protein 2.	0.978
Dll1	POFUT1	G3HNT7	P83337	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GDP-fucose protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP- fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that ca [...]	0.651
Dll1	Rbpj	G3HNT7	G3ICG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless-like protein.	0.829
Dll1	Rbpjl	G3HNT7	G3HLT2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombining binding protein suppressor of hairless-like protein.	0.455
Dll1	Rfng	G3HNT7	G3GXD4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase radical fringe.	0.652