STRINGSTRING
Gnb5 Gnb5 I79_000236 I79_000236 Trh Trh I79_000439 I79_000439 Adcy5 Adcy5 Rgs17 Rgs17 Pde4d Pde4d Prkce Prkce Gna12 Gna12 I79_002030 I79_002030 I79_002035 I79_002035 Edn3 Edn3 Gnas Gnas I79_002251 I79_002251 Agt Agt Pde6g Pde6g Gng11 Gng11 Adcy3 Adcy3 I79_002533 I79_002533 I79_002785 I79_002785 Chrm4 Chrm4 Rcvrn Rcvrn Edn1 Edn1 H671_3g9000 H671_3g9000 Oxtr Oxtr Grk6 Grk6 Rgs14 Rgs14 Cnga3 Cnga3 Ptafr Ptafr Drd2 Drd2 Htr7 Htr7 Adra1d Adra1d I79_005037 I79_005037 CgPICR_001424 CgPICR_001424 Lpar2 Lpar2 Rgs2 Rgs2 Rgs21 Rgs21 I79_005248 I79_005248 Htr4 Htr4 Adcy7 Adcy7 Brs3 Brs3 I79_006261 I79_006261 Gabbr2 Gabbr2 Kcnj9 Kcnj9 Kcnj5 Kcnj5 Gna13 Gna13 I79_006559 I79_006559 Gnai2 Gnai2 Gnat1 Gnat1 Prex1 Prex1 Cck Cck Ednra Ednra Avpr1a Avpr1a Chrm2 Chrm2 I79_007340 I79_007340 Casr Casr Trhr Trhr Nmbr Nmbr Ntsr2 Ntsr2 Calm2 Calm2 I79_007871 I79_007871 I79_008250 I79_008250 I79_008360 I79_008360 I79_008392 I79_008392 Adcy4 Adcy4 Adra1b Adra1b Pde6b Pde6b Rgs8 Rgs8 Rgs16 Rgs16 I79_009671 I79_009671 Ntsr1 Ntsr1 Bdkrb2 Bdkrb2 Bdkrb1 Bdkrb1 I79_010073 I79_010073 I79_010290 I79_010290 Chrm5 Chrm5 I79_010461 I79_010461 Gnao1 Gnao1 Gngt2 Gngt2 Pde4b Pde4b Pdcl Pdcl Rgr Rgr Gast Gast Gnai1 Gnai1 I79_012090 I79_012090 Gnal Gnal Adra1a Adra1a H671_6g15458 H671_6g15458 Kcnj3 Kcnj3 Adcy2 Adcy2 Rgs5 Rgs5 Rgs4 Rgs4 Guca1a Guca1a Guca1b Guca1b Cysltr2 Cysltr2 Lpar6 Lpar6 Git1 Git1 Aplnr Aplnr I79_013653 I79_013653 Adcy9 Adcy9 Grp Grp Gna11 Gna11 Gna15 Gna15 Tbxa2r Tbxa2r Gng7 Gng7 Opn1mw Opn1mw Avpr2 Avpr2 Rgs20 Rgs20 I79_014003 I79_014003 I79_014133 I79_014133 Opn5 Opn5 Htr6 Htr6 Lpar1 Lpar1 I79_014748 I79_014748 Kcnj6 Kcnj6 I79_014974 I79_014974 Rho Rho I79_015084 I79_015084 Gabbr1 Gabbr1 Mtnr1a Mtnr1a Grpr Grpr Kng1 Kng1 Hrg Hrg Grk4 Grk4 I79_016920 I79_016920 Agtr1 Agtr1 Rgs7bp Rgs7bp H671_1g2915 H671_1g2915 Gnb1 Gnb1 Pde7a Pde7a Chrm3 Chrm3 Cngb1 Cngb1 I79_018008 I79_018008 Gng4 Gng4 Grk2 Grk2 I79_018286 I79_018286 H671_3g9053 H671_3g9053 Agtr2 Agtr2 Gprc6a Gprc6a I79_018848 I79_018848 Gnb2 Gnb2 Adcy6 Adcy6 Adra2a Adra2a I79_019385 I79_019385 Gnat2 Gnat2 Grm1 Grm1 Grk1 Grk1 Plcb3 Plcb3 Gng2 Gng2 Gnaq Gnaq CgPICR_013836 CgPICR_013836 Ptger2 Ptger2 Lpar3 Lpar3 Rgs19 Rgs19 Grk5 Grk5 Cckar Cckar I79_021497 I79_021497 Lpar4 Lpar4 I79_021638 I79_021638 Gpr135 Gpr135 Arhgef12 Arhgef12 I79_022032 I79_022032 Cnga4 Cnga4 Cckbr Cckbr Adrb2 Adrb2 Nmb Nmb Chrm1 Chrm1 Gng3 Gng3 Kcnv2 Kcnv2 Arrb1 Arrb1 I79_024520 I79_024520 I79_024904 I79_024904 Ric8a Ric8a I79_025502 I79_025502 I79_025828 I79_025828 GNAI3 GNAI3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gnb5Guanine nucleotide-binding protein subunit beta-5. (353 aa)
I79_000236Thyrotropin-releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (476 aa)
TrhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (247 aa)
I79_000439Phosphoinositide phospholipase C. (949 aa)
Adcy5Adenylate cyclase type 5. (918 aa)
Rgs17Regulator of G-protein signaling 17. (150 aa)
Pde4dPhosphodiesterase. (507 aa)
PrkceProtein kinase C epsilon type. (137 aa)
Gna12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
I79_002030Regulator of G-protein signaling 12. (976 aa)
I79_002035Alpha-2C adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (230 aa)
Edn3Endothelin-3. (274 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (335 aa)
I79_002251Type-1 angiotensin II receptor. (117 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Pde6gRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like protein. (87 aa)
Gng11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
Adcy3Adenylate cyclase type 3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (901 aa)
I79_002533Adenylate cyclase type 3. (276 aa)
I79_002785Beta-arrestin-2. (65 aa)
Chrm4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (448 aa)
RcvrnRecoverin. (202 aa)
Edn1Endothelin-1. (202 aa)
H671_3g9000Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
OxtrOxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (353 aa)
Grk6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
Rgs14Regulator of G-protein signaling 14. (817 aa)
Cnga3Cyclic nucleotide-gated cation channel alpha-3. (1314 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Drd2D(2) dopamine receptor. (274 aa)
Htr75-hydroxytryptamine receptor 7. (391 aa)
Adra1dAlpha-1D adrenergic receptor. (485 aa)
I79_005037Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (126 aa)
CgPICR_001424Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (126 aa)
Lpar2Lysophosphatidic acid receptor 2. (50 aa)
Rgs2Regulator of G-protein signaling 2. (207 aa)
Rgs21Regulator of G-protein signaling 21. (133 aa)
I79_005248Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (149 aa)
Htr45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
Adcy7Adenylate cyclase type 7. (694 aa)
Brs3Bombesin receptor subtype-3-like protein; Belongs to the G-protein coupled receptor 1 family. (399 aa)
I79_006261Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Gabbr2Gamma-aminobutyric acid type B receptor subunit 2. (813 aa)
Kcnj9G protein-activated inward rectifier potassium channel 3. (393 aa)
Kcnj5G protein-activated inward rectifier potassium channel 4. (419 aa)
Gna13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
I79_006559Regulator of G-protein signaling 9. (492 aa)
Gnai2Guanine nucleotide-binding protein G(I), alpha-2 subunit. (338 aa)
Gnat1Guanine nucleotide-binding protein G(T) subunit alpha-1. (302 aa)
Prex1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. (1607 aa)
CckCholecystokinin. (115 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Avpr1aVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (558 aa)
I79_007340Ectonucleotide pyrophosphatase/phosphodiesterase family member 2. (592 aa)
CasrExtracellular calcium-sensing receptor. (1081 aa)
TrhrThyrotropin-releasing hormone receptor. (136 aa)
NmbrNeuromedin-B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)
Ntsr2Neurotensin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (416 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (161 aa)
I79_007871Regulator of G-protein signaling 11. (436 aa)
I79_008250Endothelin-2. (137 aa)
I79_008360Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (79 aa)
I79_008392Prostaglandin E2 receptor EP1 subtype. (434 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1022 aa)
Adra1bAlpha-1B adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (291 aa)
Pde6bPhosphodiesterase. (829 aa)
Rgs8Regulator of G-protein signaling 8. (134 aa)
Rgs16Regulator of G-protein signaling 16. (202 aa)
I79_009671Angiotensin-converting enzyme. (701 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Bdkrb2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (367 aa)
Bdkrb1B1 bradykinin receptor. (332 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
I79_010290Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
Chrm5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
I79_010461Guanine nucleotide-binding protein G(O) subunit alpha. (301 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
Gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Pde4bPhosphodiesterase. (517 aa)
PdclPhosducin-like protein. (301 aa)
RgrRPE-retinal G protein-coupled receptor. (291 aa)
GastGastrin. (104 aa)
Gnai1Guanine nucleotide-binding protein G(I), alpha-1 subunit. (302 aa)
I79_012090Guanine nucleotide-binding protein G(Olf) subunit alpha. (163 aa)
GnalGuanine nucleotide-binding protein G(Olf) subunit alpha. (131 aa)
Adra1aAlpha-1A adrenergic receptor. (465 aa)
H671_6g15458G protein-activated inward rectifier potassium channel 1-like protein. (194 aa)
Kcnj3G protein-activated inward rectifier potassium channel 1. (308 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (999 aa)
Rgs5Regulator of G-protein signaling 5. (215 aa)
Rgs4Regulator of G-protein signaling 4. (206 aa)
Guca1aGuanylyl cyclase-activating protein 1. (201 aa)
Guca1bGuanylyl cyclase-activating protein 2. (201 aa)
Cysltr2Cysteinyl leukotriene receptor 2. (322 aa)
Lpar6Oleoyl-L-alpha-lysophosphatidic acid receptor; Belongs to the G-protein coupled receptor 1 family. (344 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
I79_013653Phosphodiesterase. (801 aa)
Adcy9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (505 aa)
GrpGastrin-releasing peptide. (75 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
Gna15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
Tbxa2rThromboxane A2 receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Opn1mwGreen-sensitive opsin. (359 aa)
Avpr2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. (298 aa)
Rgs20Regulator of G-protein signaling 20. (221 aa)
I79_014003Regulator of G-protein signaling 6. (263 aa)
I79_014133Beta-adrenergic receptor kinase 2. (175 aa)
Opn5Opsin-5; Belongs to the G-protein coupled receptor 1 family. (258 aa)
Htr65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (406 aa)
Lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
I79_014748Sodium/potassium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (888 aa)
Kcnj6G protein-activated inward rectifier potassium channel 2. (331 aa)
I79_014974Beta-adrenergic receptor kinase 2; Belongs to the protein kinase superfamily. (338 aa)
RhoRhodopsin. (348 aa)
I79_015084Gamma-aminobutyric acid type B receptor subunit 1. (281 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1. (401 aa)
Mtnr1aMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (353 aa)
GrprGastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
Kng1Kininogen-1-like protein. (136 aa)
HrgKininogen-1. (574 aa)
Grk4G protein-coupled receptor kinase 4. (168 aa)
I79_016920Rho guanine nucleotide exchange factor 1. (791 aa)
Agtr1Type-1A angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Rgs7bpRegulator of G-protein signaling 7-binding protein. (125 aa)
H671_1g2915Guanine nucleotide-binding protein subunit beta-4-like protein. (364 aa)
Gnb1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
Pde7aPhosphodiesterase. (438 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (589 aa)
Cngb1Cyclic nucleotide-gated cation channel beta-1. (141 aa)
I79_018008Cyclic nucleotide-gated cation channel beta-1. (897 aa)
Gng4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Grk2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
I79_018286Cyclic nucleotide-gated olfactory channel. (650 aa)
H671_3g9053Glycerophosphodiester phosphodiesterase domain-containing protein 3. (302 aa)
Agtr2Type-2 angiotensin II receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Gprc6aG-protein coupled receptor family C group 6 member A. (928 aa)
I79_018848Prostacyclin receptor. (229 aa)
Gnb2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (280 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
Adra2aAlpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
I79_019385Guanine nucleotide-binding protein G(T) subunit alpha-2. (69 aa)
Gnat2Guanine nucleotide-binding protein G(T) subunit alpha-2. (157 aa)
Grm1Metabotropic glutamate receptor 1. (898 aa)
Grk1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (564 aa)
Plcb3Phosphoinositide phospholipase C. (1231 aa)
Gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (220 aa)
CgPICR_013836Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
Ptger2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (360 aa)
Lpar3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (352 aa)
Rgs19Regulator of G-protein signaling 19. (209 aa)
Grk5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (140 aa)
CckarCholecystokinin receptor type A. (205 aa)
I79_021497S-arrestin. (327 aa)
Lpar4Lysophosphatidic acid receptor 4 isoform 2; Belongs to the G-protein coupled receptor 1 family. (370 aa)
I79_021638Guanine nucleotide-binding protein subunit alpha-14. (282 aa)
Gpr135Putative G-protein coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (457 aa)
Arhgef12Rho guanine nucleotide exchange factor 12. (371 aa)
I79_022032Calcium-binding protein 5. (200 aa)
Cnga4Cyclic nucleotide-gated cation channel alpha-4. (535 aa)
CckbrGastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
Adrb2Beta-2 adrenergic receptor. (337 aa)
NmbNeuromedin-B. (55 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Kcnv2Potassium voltage-gated channel subfamily V member 2; Belongs to the potassium channel family. (562 aa)
Arrb1Beta-arrestin-1. (422 aa)
I79_024520Guanine nucleotide-binding protein subunit alpha-11. (61 aa)
I79_024904Guanine nucleotide-binding protein G(Q) subunit alpha. (112 aa)
Ric8aSynembryn-A. (494 aa)
I79_025502Adenylate cyclase type 8. (333 aa)
I79_025828Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (184 aa)
GNAI3Guanine nucleotide binding protein alpha inhibiting 3. (354 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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