STRINGSTRING
I79_017833 I79_017833 Gata3 Gata3 Foxp1 Foxp1 I79_000398 I79_000398 I79_000801 I79_000801 Bcl6 Bcl6 Suz12 Suz12 Cit Cit Chd4 Chd4 I79_001487 I79_001487 Mafk Mafk Foxp2 Foxp2 Zbtb49 Zbtb49 Baiap2 Baiap2 Ezh2 Ezh2 Foxo3 Foxo3 Vamp2 Vamp2 Lmo2 Lmo2 Pax6 Pax6 Ccnt2 Ccnt2 Lcor Lcor Thrb Thrb Nfe2l2 Nfe2l2 I79_004407 I79_004407 Cbx3 Cbx3 Tfam Tfam Rpl23 Rpl23 Med1 Med1 Smarca4 Smarca4 Ets1 Ets1 Smad3 Smad3 Hdac1 Hdac1 I79_006923 I79_006923 I79_006924 I79_006924 Ctnnb1 Ctnnb1 I79_007328 I79_007328 I79_007329 I79_007329 Smarcd3 Smarcd3 Ube2i Ube2i CgPICR_014717 CgPICR_014717 Nfatc1 Nfatc1 I79_008916 I79_008916 Mtf2 Mtf2 Fos Fos Thap7 Thap7 Hdgf Hdgf I79_010155 I79_010155 Hdac2 Hdac2 I79_010330 I79_010330 Gata2 Gata2 Ctbp1 Ctbp1 Pbx1 Pbx1 Hdac5 Hdac5 Wiz Wiz Runx3 Runx3 Creb3 Creb3 Hdac6 Hdac6 Gata1 Gata1 I79_012375 I79_012375 I79_012376 I79_012376 Runx1 Runx1 Lcorl Lcorl Trerf1 Trerf1 I79_013437 I79_013437 Ppard Ppard I79_013706 I79_013706 I79_013707 I79_013707 MED6 MED6 Ahr Ahr Smad4 Smad4 I79_014474 I79_014474 Cdk9 Cdk9 I79_014810 I79_014810 Sp1 Sp1 Ctbp2 Ctbp2 PPARG PPARG Vgll4 Vgll4 I79_015156 I79_015156 I79_015405 I79_015405 Chd6 Chd6 I79_015503 I79_015503 Eed Eed Hif1a Hif1a Ehmt2 Ehmt2 Ctcf Ctcf Foxo1 Foxo1 I79_016660 I79_016660 I79_016692 I79_016692 Hnf4a Hnf4a Znf644 Znf644 I79_017134 I79_017134 Zbtb16 Zbtb16 I79_017450 I79_017450 Per2 Per2 Ep300 Ep300 H671_4g12945 H671_4g12945 Nr1d1 Nr1d1 I79_018785 I79_018785 Ehmt1 Ehmt1 Hnf1b Hnf1b Phf1 Phf1 I79_019286 I79_019286 Med25 Med25 Phf12 Phf12 Zbtb17 Zbtb17 I79_019731 I79_019731 Nek6 Nek6 Nr5a1 Nr5a1 Stat1 Stat1 I79_020203 I79_020203 Nfya Nfya Klf4 Klf4 Usp11 Usp11 I79_020986 I79_020986 I79_021251 I79_021251 Nr5a2 Nr5a2 Rela Rela I79_021840 I79_021840 Rxra Rxra Six1 Six1 I79_022078 I79_022078 I79_022390 I79_022390 Ppara Ppara Elob Elob Epas1 Epas1 Rora Rora Fam89b Fam89b Ar Ar I79_023042 I79_023042 I79_023104 I79_023104 I79_023241 I79_023241 I79_023275 I79_023275 I79_024048 I79_024048 I79_024078 I79_024078 I79_024087 I79_024087 I79_024314 I79_024314 I79_024415 I79_024415 I79_025454 I79_025454 Myc Myc I79_025745 I79_025745 I79_025851 I79_025851 Tert Tert
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Foxp1Forkhead box protein P1. (696 aa)
I79_000398Transcription elongation factor B polypeptide 2. (99 aa)
I79_000801Histone deacetylase 1. (92 aa)
Bcl6B-cell lymphoma 6 protein-like. (707 aa)
Suz12Polycomb protein Suz12. (200 aa)
CitCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2056 aa)
Chd4Chromodomain-helicase-DNA-binding protein 4. (1930 aa)
I79_001487Progesterone receptor. (741 aa)
MafkTranscription factor MafK-like protein. (156 aa)
Foxp2Forkhead box protein P2. (492 aa)
Zbtb49Zinc finger protein 509. (678 aa)
Baiap2Brain-specific angiogenesis inhibitor 1-associated protein 2. (555 aa)
Ezh2Histone-lysine N-methyltransferase EZH2. (746 aa)
Foxo3Forkhead box protein O3. (672 aa)
Vamp2Period circadian protein-like 1. (1281 aa)
Lmo2Rhombotin-2. (151 aa)
Pax6Paired box protein Pax-6. (544 aa)
Ccnt2Cyclin-T2; Belongs to the cyclin family. (724 aa)
LcorUncharacterized protein C10orf12. (1568 aa)
ThrbThyroid hormone receptor beta. (377 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
I79_004407Transcription elongation factor B polypeptide 2. (92 aa)
Cbx3Chromobox protein-like 3. (191 aa)
TfamTranscription factor A, mitochondrial. (190 aa)
Rpl2360S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (140 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
Ets1Protein C-ets-1. (257 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
I79_006923Histone deacetylase 1. (235 aa)
I79_006924Histone deacetylase 1. (188 aa)
Ctnnb1Catenin beta-1. (781 aa)
I79_007328Histone deacetylase 2. (91 aa)
I79_007329Histone deacetylase 1. (250 aa)
Smarcd3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (300 aa)
Ube2iSUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
CgPICR_014717CTBP2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (272 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
I79_008916Metal-response element-binding transcription factor 2. (109 aa)
Mtf2Metal-response element-binding transcription factor 2. (378 aa)
FosProto-oncogene protein c-fos. (381 aa)
Thap7THAP domain-containing protein 7. (308 aa)
HdgfHepatoma-derived growth factor. (205 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Ctbp1Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (422 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
Hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1081 aa)
WizProtein Wiz. (1722 aa)
Runx3Runt-related transcription factor 3. (299 aa)
Creb3Cyclic AMP-responsive element-binding protein 3. (379 aa)
Hdac6Histone deacetylase 6. (666 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
I79_012375Transcription elongation factor B polypeptide 2. (75 aa)
I79_012376Transcription elongation factor B polypeptide 2. (76 aa)
Runx1Runt-related transcription factor 1. (462 aa)
LcorlUncharacterized protein. (579 aa)
Trerf1Transcriptional-regulating factor 1. (1199 aa)
I79_013437Nuclear receptor subfamily 4 group A member 3. (598 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
I79_013706CREB-binding protein. (759 aa)
I79_013707CREB-binding protein. (202 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (191 aa)
AhrAryl hydrocarbon receptor. (247 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
Cdk9Cell division protein kinase 9; Belongs to the protein kinase superfamily. (372 aa)
I79_014810Cyclic AMP-dependent transcription factor ATF-7. (483 aa)
Sp1Transcription factor Sp1. (778 aa)
Ctbp2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Vgll4Transcription cofactor vestigial-like protein 4. (282 aa)
I79_01515660S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (81 aa)
I79_015405Chromodomain-helicase-DNA-binding protein 6. (699 aa)
Chd6Chromodomain-helicase-DNA-binding protein 6. (2031 aa)
I79_015503Transcription factor HES-1. (92 aa)
EedPolycomb protein EED. (262 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Ehmt2Histone-lysine N-methyltransferase, H3 lysine-9 specific 3. (661 aa)
CtcfTranscriptional repressor CTCF. (734 aa)
Foxo1Forkhead box protein O1. (469 aa)
I79_016660Transcriptional enhancer factor TEF-4. (375 aa)
I79_016692CREB-binding protein. (1054 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
Znf644Zinc finger protein 644. (1246 aa)
I79_017134Trafficking protein particle complex subunit 2. (163 aa)
Zbtb16Zinc finger and BTB domain-containing protein 16. (423 aa)
I79_017450Zinc finger and BTB domain-containing protein 16. (236 aa)
Per2Period circadian protein-like 2. (1262 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
H671_4g1294560S ribosomal protein L23-like protein; Belongs to the universal ribosomal protein uL14 family. (128 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
I79_018785Retinoic acid receptor alpha. (484 aa)
Ehmt1Histone-lysine N-methyltransferase, H3 lysine-9 specific 5. (1257 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Phf1PHD finger protein 1. (568 aa)
I79_019286Androgen receptor. (295 aa)
Med25Mediator of RNA polymerase II transcription subunit 25. (735 aa)
Phf12PHD finger protein 12. (195 aa)
Zbtb17Zinc finger and BTB domain-containing protein 17. (384 aa)
I79_019731Zinc finger and BTB domain-containing protein 17. (142 aa)
Nek6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (313 aa)
Nr5a1Steroidogenic factor 1. (462 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
I79_020203Protein piccolo. (3863 aa)
NfyaNuclear transcription factor Y subunit alpha. (347 aa)
Klf4Krueppel-like factor 4. (474 aa)
Usp11Ubiquitin carboxyl-terminal hydrolase 11; Belongs to the peptidase C19 family. (471 aa)
I79_020986Ubiquitin carboxyl-terminal hydrolase 11; Belongs to the peptidase C19 family. (447 aa)
I79_021251High mobility group protein HMG-I/HMG-Y. (70 aa)
Nr5a2Nuclear receptor subfamily 5 group A member 2. (301 aa)
RelaTranscription factor p65. (546 aa)
I79_021840Nuclear receptor ROR-gamma. (341 aa)
RxraRetinoic acid receptor RXR-alpha. (439 aa)
Six1Homeobox protein SIX1. (284 aa)
I79_022078Homeobox protein Nkx-2.1. (190 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
ElobTranscription elongation factor B polypeptide 2. (267 aa)
Epas1Endothelial PAS domain-containing protein 1. (878 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
Fam89bProtein FAM89B. (85 aa)
ArAndrogen receptor. (517 aa)
I79_023042Transcription elongation factor B polypeptide 2. (118 aa)
I79_023104CCR4-NOT transcription complex subunit 2. (417 aa)
I79_023241Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (558 aa)
I79_023275Zinc finger protein 420. (492 aa)
I79_024048Paired box protein Pax-3. (324 aa)
I79_024078Period circadian protein-like 3. (949 aa)
I79_024087Transcriptional enhancer factor TEF-4. (198 aa)
I79_024314Paired box protein Pax-3. (301 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
I79_025851Ubiquitin carboxyl-terminal hydrolase 11. (342 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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