STRINGSTRING
Limd1 Limd1 I79_003100 I79_003100 Lep Lep Lct Lct Cxcr4 Cxcr4 Edn1 Edn1 Mmp2 Mmp2 Cav3 Cav3 I79_003972 I79_003972 Eif4ebp1 Eif4ebp1 Zfp36l1 Zfp36l1 Slc8a3 Slc8a3 Nfe2l2 Nfe2l2 Atf2 Atf2 Oprd1 Oprd1 I79_004214 I79_004214 Cryab Cryab Il18 Il18 Drd2 Drd2 I79_004403 I79_004403 I79_004653 I79_004653 Akt1 Akt1 Adora1 Adora1 Scfd1 Scfd1 I79_005344 I79_005344 I79_005799 I79_005799 I79_005909 I79_005909 I79_005993 I79_005993 Stox1 Stox1 Angpt4 Angpt4 I79_006155 I79_006155 I79_006409 I79_006409 Alas2 Alas2 I79_006650 I79_006650 Mst1 Mst1 Smad3 Smad3 Prmt2 Prmt2 Higd1a Higd1a Ednra Ednra Cav1 Cav1 Stc2 Stc2 Pink1 Pink1 Tbl2 Tbl2 Sirt1 Sirt1 E2f1 E2f1 Mgarp Mgarp I79_007576 I79_007576 Cdkn1b Cdkn1b I79_007744 I79_007744 Angpt2 Angpt2 Pck1 Pck1 I79_007865 I79_007865 I79_007866 I79_007866 Tsc2 Tsc2 Stub1 Stub1 Ciao3 Ciao3 Chrnb2 Chrnb2 Pklr Pklr Adam15 Adam15 I79_008089 I79_008089 P2rx2 P2rx2 LONP1 LONP1 Wdr83 Wdr83 Tm9sf4 Tm9sf4 Tgfbr3 Tgfbr3 Pml Pml Ptgis Ptgis Egr1 Egr1 Slc2a1 Slc2a1 Mpl Mpl I79_009416 I79_009416 Pgf Pgf Tgfb3 Tgfb3 Lmna Lmna Vegfc Vegfc Rgcc Rgcc Chrna4 Chrna4 I79_009953 I79_009953 I79_009958 I79_009958 I79_009992 I79_009992 Prkaa1 Prkaa1 Dkk4 Dkk4 Sfrp1 Sfrp1 Alad Alad I79_010470 I79_010470 I79_010748 I79_010748 I79_010749 I79_010749 I79_010752 I79_010752 Actn4 Actn4 Sirt2 Sirt2 Fabp1 Fabp1 Aqp1 Aqp1 I79_010923 I79_010923 Rtn4 Rtn4 I79_011076 I79_011076 I79_011096 I79_011096 Map3k2 Map3k2 Scap Scap Nfatc3 Nfatc3 Hspd1 Hspd1 Grin2b Grin2b Cbs Cbs Ada Ada I79_011711 I79_011711 Becn1 Becn1 Ca9 Ca9 I79_012135 I79_012135 Suv39h1 Suv39h1 I79_012336 I79_012336 I79_012424 I79_012424 I79_012425 I79_012425 Atp7a Atp7a I79_012903 I79_012903 Pdk3 Pdk3 I79_013032 I79_013032 Ddr2 Ddr2 Hsp90b1 Hsp90b1 Slc6a4 Slc6a4 I79_013395 I79_013395 Ajuba Ajuba P2rx3 P2rx3 Ppard Ppard Hmox2 Hmox2 Vasn Vasn Mecp2 Mecp2 Irak1 Irak1 Nr4a2 Nr4a2 Ndnf Ndnf Kcnd2 Kcnd2 Kcnmb1 Kcnmb1 I79_014261 I79_014261 Smad4 Smad4 Cflar Cflar I79_014629 I79_014629 Wtip Wtip Slc2a8 Slc2a8 Psen2 Psen2 PPARG PPARG I79_015057 I79_015057 I79_015073 I79_015073 Adsl Adsl B3gat1 B3gat1 Fundc1 Fundc1 Sod2 Sod2 Fndc1 Fndc1 I79_015356 I79_015356 Cat Cat CgPICR_014700 CgPICR_014700 I79_015795 I79_015795 Itpr2 Itpr2 Pdlim1 Pdlim1 Ascl2 Ascl2 H671_3g9558 H671_3g9558 Ak4 Ak4 Bnip3l Bnip3l I79_016007 I79_016007 Adipoq Adipoq Adm Adm Slc9a1 Slc9a1 Srf Srf I79_016240 I79_016240 I79_016282 I79_016282 Hif1a Hif1a Hif1an Hif1an Ager Ager I79_016423 I79_016423 Tnf Tnf Lta Lta Hsd11b2 Hsd11b2 I79_016618 I79_016618 I79_016810 I79_016810 H671_3g9603 H671_3g9603 Gnb1 Gnb1 Ddit4 Ddit4 I79_017529 I79_017529 I79_017669 I79_017669 I79_018020 I79_018020 Hp1bp3 Hp1bp3 H671_3g9048 H671_3g9048 I79_018438 I79_018438 Ep300 Ep300 I79_018586 I79_018586 Angptl4 Angptl4 I79_018842 I79_018842 Epo Epo I79_019042 I79_019042 Brip1 Brip1 Cxcl12 Cxcl12 Vegfb Vegfb Rest Rest NADH4 NADH4 NADH5 NADH5 cytb cytb I79_026218 I79_026218 Tert Tert Myc Myc I79_025720 I79_025720 I79_025593 I79_025593 CgPICR_017963 CgPICR_017963 I79_025512 I79_025512 I79_025454 I79_025454 I79_025297 I79_025297 Txn2 Txn2 I79_025189 I79_025189 Nppc Nppc Egln3 Egln3 CgPICR_017246 CgPICR_017246 Pak1 Pak1 Mb Mb I79_024415 I79_024415 I79_024407 I79_024407 I79_024097 I79_024097 Plekhn1 Plekhn1 I79_023665 I79_023665 I79_023615 I79_023615 Agtrap Agtrap Mthfr Mthfr I79_023268 I79_023268 Mief1 Mief1 I79_023146 I79_023146 I79_023016 I79_023016 I79_000054 I79_000054 Ucn3 Ucn3 Hk2 Hk2 Rora Rora Bnip3 Bnip3 Epas1 Epas1 Slc11a2 Slc11a2 Ppara Ppara I79_022390 I79_022390 I79_022301 I79_022301 I79_022300 I79_022300 I79_022295 I79_022295 Mtor Mtor I79_022034 I79_022034 Sod3 Sod3 Vcam1 Vcam1 Cpeb1 Cpeb1 Rbpj Rbpj Acvrl1 Acvrl1 I79_021045 I79_021045 I79_020705 I79_020705 Adam8 Adam8 Aqp3 Aqp3 Hmox1 Hmox1 I79_020544 I79_020544 I79_020508 I79_020508 Tgfb1 Tgfb1 Ucp3 Ucp3 Nox4 Nox4 Hyou1 Hyou1 I79_000092 I79_000092 Kcnk2 Kcnk2 Cbfa2t3 Cbfa2t3 I79_000233 I79_000233 Trh Trh Tfrc Tfrc Bach1 Bach1 Lyrm9 Lyrm9 I79_001046 I79_001046 CgPICR_003438 CgPICR_003438 Nos1 Nos1 SIRT4 SIRT4 Pdk1 Pdk1 Tigar Tigar Kcna5 Kcna5 Tnfrsf1a Tnfrsf1a Phb2 Phb2 Loxl2 Loxl2 Stc1 Stc1 I79_001592 I79_001592 Prkce Prkce Tgfbr2 Tgfbr2 I79_001728 I79_001728 Abat Abat Suv39h2 Suv39h2 Fosl2 Fosl2 I79_002099 I79_002099 I79_002157 I79_002157 I79_002177 I79_002177 I79_002178 I79_002178 Kcnma1 Kcnma1 I79_002195 I79_002195 Ptgs2 Ptgs2 I79_002290 I79_002290 Vhl Vhl P4hb P4hb Narf Narf Foxo3 Foxo3 Kcnk3 Kcnk3 Src Src Slc2a4 Slc2a4 Plk3 Plk3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Limd1LIM domain-containing protein 1. (667 aa)
I79_003100Myocardin. (371 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LctDNA helicase; Belongs to the MCM family. (2669 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
Edn1Endothelin-1. (202 aa)
Mmp272 kDa type IV collagenase. (662 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
I79_00397260 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family. (104 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (117 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
Slc8a3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2. (487 aa)
Oprd1Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (323 aa)
I79_004214FUN14 domain-containing protein 1. (136 aa)
CryabAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (196 aa)
Drd2D(2) dopamine receptor. (274 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
I79_004653Inositol 1,4,5-trisphosphate receptor type 1. (2569 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Scfd1Sec1 family domain-containing protein 1; Belongs to the STXBP/unc-18/SEC1 family. (634 aa)
I79_005344Adenylate kinase isoenzyme 4, mitochondrial. (106 aa)
I79_005799Neuroglobin; Belongs to the globin family. (164 aa)
I79_005909Peptidyl-prolyl cis-trans isomerase. (242 aa)
I79_005993Formin-2. (877 aa)
Stox1Storkhead-box protein 1. (834 aa)
Angpt4Angiopoietin-4. (499 aa)
I79_006155Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (146 aa)
I79_0064095-aminolevulinate synthase, erythroid-specific, mitochondrial. (60 aa)
Alas25-aminolevulinate synthase, erythroid-specific, mitochondrial. (114 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Prmt2Protein arginine N-methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (445 aa)
Higd1aHIG1 domain family member 1A. (128 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Stc2Stanniocalcin-2. (297 aa)
Pink1Serine/threonine-protein kinase PINK1, mitochondrial. (451 aa)
Tbl2Transducin beta-like protein 2. (351 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
E2f1Transcription factor E2F1. (367 aa)
MgarpUncharacterized protein C4orf49. (103 aa)
I79_007576Protein Mdm4. (405 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
I79_007744Angiopoietin-2. (188 aa)
Angpt2Angiopoietin-2. (288 aa)
Pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
I79_007865Sodium channel protein type 2 subunit alpha. (218 aa)
I79_007866Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (668 aa)
Tsc2Tuberin. (1546 aa)
Stub1STIP1-likey and U box-containing protein 1. (231 aa)
Ciao3Cytosolic Fe-S cluster assembly factor NARFL; Belongs to the NARF family. (476 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2. (495 aa)
PklrPyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
Adam15Disintegrin and metalloproteinase domain-containing protein 15. (844 aa)
I79_008089Equilibrative nucleoside transporter 1. (184 aa)
P2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (504 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (842 aa)
Wdr83Mitogen-activated protein kinase organizer 1. (315 aa)
Tm9sf4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (301 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
PmlPutative transcription factor PML. (540 aa)
PtgisProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
MplThrombopoietin receptor. (647 aa)
I79_009416Serine-protein kinase ATM. (1640 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
LmnaLamin-A/C; Belongs to the intermediate filament family. (563 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
RgccResponse gene to complement 32 protein. (153 aa)
Chrna4Neuronal acetylcholine receptor subunit alpha-4. (627 aa)
I79_009953Transcription factor AP-1. (72 aa)
I79_009958Angiopoietin-1 receptor. (793 aa)
I79_009992Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (259 aa)
Prkaa1Non-specific serine/threonine protein kinase. (477 aa)
Dkk4Salivary plasminogen activator alpha 2. (675 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
AladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
I79_010470Metallothionein-3; Belongs to the metallothionein superfamily. Type 1 family. (108 aa)
I79_010748Ryanodine receptor 1. (1261 aa)
I79_010749Ryanodine receptor 1. (1965 aa)
I79_010752Alpha-actinin-4. (327 aa)
Actn4Alpha-actinin-4. (234 aa)
Sirt2NAD-dependent deacetylase sirtuin-2. (83 aa)
Fabp1Fatty acid-binding protein, liver. (149 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
I79_010923Reticulon. (68 aa)
Rtn4Reticulon-4. (806 aa)
I79_011076Coagulation factor X. (629 aa)
I79_011096Transforming acidic coiled-coil-containing protein 3. (580 aa)
Map3k2TFIIH basal transcription factor complex helicase XPB subunit. (1183 aa)
ScapSterol regulatory element-binding protein cleavage-activating protein. (1276 aa)
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3. (1075 aa)
Hspd160 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (526 aa)
Grin2bGlutamate [NMDA] receptor subunit epsilon-2. (1373 aa)
CbsCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (561 aa)
AdaAdenosine deaminase. (363 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
Becn1Beclin-1. (448 aa)
Ca9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (182 aa)
I79_012135Carbonic anhydrase 9. (114 aa)
Suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
I79_012424Ryanodine receptor 2. (2535 aa)
I79_012425Ryanodine receptor 2. (2233 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
I79_012903Pulmonary surfactant-associated protein A. (238 aa)
Pdk3Protein-serine/threonine kinase. (415 aa)
I79_013032Peptidyl-glycine alpha-amidating monooxygenase B. (851 aa)
Ddr2Discoidin domain-containing receptor 2. (854 aa)
Hsp90b1Endoplasmin. (803 aa)
Slc6a4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (520 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
AjubaProtein ajuba. (214 aa)
P2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (464 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
Hmox2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
VasnVasorin. (673 aa)
Mecp2Methyl-CpG-binding protein 2. (203 aa)
Irak1Interleukin-1 receptor-associated kinase 1. (494 aa)
Nr4a2Nuclear receptor subfamily 4 group A member 2. (598 aa)
NdnfFibronectin type-III domain-containing protein C4orf31-like. (567 aa)
Kcnd2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
Kcnmb1Calcium-activated potassium channel subunit beta-1. (191 aa)
I79_014261Cytoplasmic polyadenylation element-binding protein 2. (422 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
CflarCASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (484 aa)
I79_014629Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (369 aa)
WtipWilms tumor protein 1-interacting protein. (133 aa)
Slc2a8Solute carrier family 2, facilitated glucose transporter member 8. (315 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_015057Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (587 aa)
I79_015073Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (277 aa)
AdslAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (484 aa)
B3gat1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (509 aa)
Fundc1FUN14 domain-containing protein 1. (133 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
Fndc1Fibronectin type III domain-containing protein 1. (1766 aa)
I79_015356Heat shock factor protein 1. (524 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
CgPICR_014700C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
I79_015795Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (284 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (470 aa)
Pdlim1PDZ and LIM domain protein 1. (329 aa)
Ascl2Achaete-scute-like 2. (193 aa)
H671_3g9558Tyrosine 3-monooxygenase-like protein. (542 aa)
Ak4Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (161 aa)
Bnip3lBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (179 aa)
I79_016007Cytochrome b-245 heavy chain. (396 aa)
AdipoqAdiponectin. (248 aa)
AdmProcalcitonin/adrenomedullin containing protein. (184 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
SrfSerum response factor. (361 aa)
I79_016240Beclin-1. (119 aa)
I79_016282DNA repair protein XRCC1. (460 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Hif1anHypoxia-inducible factor 1-alpha inhibitor. (312 aa)
AgerAdvanced glycosylation end product-specific receptor. (334 aa)
I79_016423Advanced glycosylation end product-specific receptor. (65 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
LtaLymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
Hsd11b2Corticosteroid 11-beta-dehydrogenase isozyme 2. (312 aa)
I79_016618Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (470 aa)
I79_016810Serine-protein kinase ATM. (473 aa)
H671_3g960360 kDa heat shock protein, mitochondrial. (141 aa)
Gnb1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
Ddit4DNA-damage-inducible transcript 4 protein. (231 aa)
I79_017529Apoptotic protease-activating factor 1. (444 aa)
I79_017669Apoptotic protease-activating factor 1. (434 aa)
I79_018020Mitogen-activated protein kinase organizer 1. (141 aa)
Hp1bp3Heterochromatin protein 1-binding protein 3. (561 aa)
H671_3g9048Fructose-1,6-bisphosphate aldolase A-like protein. (139 aa)
I79_018438Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (202 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Angptl4Angiopoietin-related protein 4. (411 aa)
I79_018842Hypoxia-inducible factor 3 alpha. (272 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
I79_01904260 kDa heat shock protein, mitochondrial. (169 aa)
Brip1Fanconi anemia group J protein-like. (1166 aa)
Cxcl12Stromal cell-derived factor 1. (89 aa)
VegfbVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
RestRE1-silencing transcription factor. (1047 aa)
NADH4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
NADH5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (606 aa)
cytbCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
I79_026218Calcium/calmodulin-dependent protein kinase type II delta chain. (64 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025720Corticotropin-releasing factor receptor 1. (134 aa)
I79_025593Protein NDRG1. (129 aa)
CgPICR_017963Egl nine-like 3, mitochondrial. (148 aa)
I79_025512Urotensin-2. (88 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
I79_025297Very low-density lipoprotein receptor. (558 aa)
Txn2Thioredoxin, mitochondrial. (64 aa)
I79_025189Protein NDRG1. (323 aa)
NppcC-type natriuretic peptide. (126 aa)
Egln3Egl nine-like 3. (135 aa)
CgPICR_017246Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
MbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
I79_02440760 kDa heat shock protein, mitochondrial. (214 aa)
I79_024097Vascular cell adhesion protein 1. (225 aa)
Plekhn1Pleckstrin-likey domain-containing family N member 1. (247 aa)
I79_023665Calcium-activated chloride channel regulator 1. (968 aa)
I79_023615Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (659 aa)
AgtrapType-1 angiotensin II receptor-associated protein. (160 aa)
MthfrMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (644 aa)
I79_023268Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
Mief1Smith-Magenis syndrome chromosome region candidate gene 7 protein-like. (463 aa)
I79_023146Aryl hydrocarbon receptor nuclear translocator 2. (506 aa)
I79_023016Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (250 aa)
I79_000054Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (668 aa)
Ucn3Urocortin-3. (162 aa)
Hk2Hexokinase-2. (704 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
Bnip3BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (151 aa)
Epas1Endothelial PAS domain-containing protein 1. (878 aa)
Slc11a2Natural resistance-associated macrophage protein 2. (474 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
I79_022301Calcium/calmodulin-dependent protein kinase type II delta chain. (225 aa)
I79_02230060 kDa heat shock protein, mitochondrial. (252 aa)
I79_022295Dynamin-1-like protein. (310 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
Sod3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (245 aa)
Vcam1Vascular cell adhesion protein 1. (220 aa)
Cpeb1Cytoplasmic polyadenylation element-binding protein 1. (481 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
I79_021045Heme oxygenase 1. (81 aa)
I79_020705Ubiquilin-1. (168 aa)
Adam8Disintegrin and metalloproteinase domain-containing protein 8. (936 aa)
Aqp3Aquaporin-3. (554 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
I79_020544Egl nine-like 3, mitochondrial. (152 aa)
I79_020508Protein NDRG1. (263 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Ucp3Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (650 aa)
Nox4NADPH oxidase 4. (130 aa)
Hyou1Hypoxia up-regulated protein 1. (999 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Kcnk2Potassium channel subfamily K member 2. (215 aa)
Cbfa2t3Protein CBFA2T3. (593 aa)
I79_000233Cytochrome b-245 light chain. (206 aa)
TrhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (247 aa)
TfrcTransferrin receptor protein 1. (757 aa)
Bach1Transcription regulator protein BACH1. (742 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
I79_001046Neurofibromin. (2164 aa)
CgPICR_003438C-C motif chemokine. (143 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (255 aa)
Pdk1Protein-serine/threonine kinase. (344 aa)
TigarPutative fructose-2,6-bisphosphatase TIGAR. (266 aa)
Kcna5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (603 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
Phb2Prohibitin-2. (396 aa)
Loxl2Lysyl oxidase-like 2. (300 aa)
Stc1Stanniocalcin-1. (247 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
PrkceProtein kinase C epsilon type. (137 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
I79_001728Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (473 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
Suv39h2Histone-lysine N-methyltransferase SUV39H2. (542 aa)
Fosl2Fos-related antigen 2. (323 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
I79_002157Phosphotransferase. (266 aa)
I79_002177Calcium/calmodulin-dependent protein kinase type II gamma chain. (507 aa)
I79_002178Urokinase-type plasminogen activator; Belongs to the peptidase S1 family. (397 aa)
Kcnma1Uncharacterized protein. (462 aa)
I79_002195Calcium-activated potassium channel subunit alpha-1. (326 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
I79_002290Egl nine-like 1. (183 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (134 aa)
P4hbProtein disulfide-isomerase; Belongs to the protein disulfide isomerase family. (184 aa)
NarfNuclear prelamin A recognition factor; Belongs to the NARF family. (331 aa)
Foxo3Forkhead box protein O3. (672 aa)
Kcnk3Potassium channel subfamily K member 3. (314 aa)
SrcTyrosine-protein kinase. (536 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4. (90 aa)
Plk3Uncharacterized protein. (611 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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