STRINGSTRING
E2f8 E2f8 I79_008633 I79_008633 I79_008294 I79_008294 Pkd1 Pkd1 Bmp7 Bmp7 I79_026041 I79_026041 Rspo3 Rspo3 I79_000120 I79_000120 CgPICR_012052 CgPICR_012052 St14 St14 Il10 Il10 Wnt2 Wnt2 Ggnbp2 Ggnbp2 Ncoa3 Ncoa3 I79_006792 I79_006792 Med1 Med1 Nodal Nodal Csf2 Csf2 Hectd1 Hectd1 Socs3 Socs3 Akt1 Akt1 Hs6st1 Hs6st1 Zfp36l1 Zfp36l1 Sox15 Sox15 Ncoa1 Ncoa1 I79_002290 I79_002290 I79_001871 I79_001871 Plcd1 Plcd1 Eomes Eomes Sp3 Sp3 Ncoa6 Ncoa6 I79_007335 I79_007335 Gjb5 Gjb5 I79_025625 I79_025625 Map2k1 Map2k1 I79_024483 I79_024483 Fgfr2 Fgfr2 I79_024097 I79_024097 I79_023578 I79_023578 I79_023577 I79_023577 I79_023549 I79_023549 I79_023275 I79_023275 Krt8 Krt8 Nsdhl Nsdhl Nfe2 Nfe2 Epas1 Epas1 Taf10 Taf10 Vcam1 Vcam1 Spint1 Spint1 Wnt7b Wnt7b Rbpj Rbpj Hey2 Hey2 I79_020212 I79_020212 I79_019825 I79_019825 Gcm1 Gcm1 Rtl1 Rtl1 I79_017833 I79_017833 Trim28 Trim28 Pdgfb Pdgfb Lif Lif Tfeb Tfeb Ttpal Ttpal I79_016918 I79_016918 Rtl5 Rtl5 I79_016797 I79_016797 I79_016362 I79_016362 Hif1a Hif1a Adm Adm I79_016057 I79_016057 I79_015916 I79_015916 Ascl2 Ascl2 Cdkn1c Cdkn1c Tmed2 Tmed2 I79_015503 I79_015503 I79_015356 I79_015356 Prdm1 Prdm1 I79_015033 I79_015033 Sp1 Sp1 I79_014629 I79_014629 I79_014483 I79_014483 Fzd5 Fzd5 E2f7 E2f7 Plk4 Plk4 Syde1 Syde1 Stk4 Stk4 Plcd3 Plcd3 I79_011377 I79_011377 Setd2 Setd2 I79_011258 I79_011258 Stk3 Stk3 I79_010743 I79_010743 I79_010700 I79_010700 Gata2 Gata2 I79_009796 I79_009796 Plac1 Plac1 I79_009500 I79_009500 Vash1 Vash1 I79_009443 I79_009443 Birc6 Birc6 Snai1 Snai1 I79_009066 I79_009066 I79_008941 I79_008941
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2f8Transcription factor E2F8. (867 aa)
I79_008633Integrin alpha-4; Belongs to the integrin alpha chain family. (441 aa)
I79_008294Nucleosome-remodeling factor subunit BPTF. (1784 aa)
Pkd1Polycystin-1. (3717 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
I79_026041Zinc finger protein ZFAT. (67 aa)
Rspo3R-spondin-3. (81 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
CgPICR_012052Growth factor receptor-bound protein 2. (217 aa)
St14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (827 aa)
Il10Interleukin-10. (178 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Ggnbp2Gametogenetin-binding protein 2. (667 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
NodalNodal. (309 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (95 aa)
Hectd1E3 ubiquitin-protein ligase HECTD1. (2610 aa)
Socs3Suppressor of cytokine signaling 3. (225 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Hs6st1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (202 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
Sox15Protein SOX-15. (149 aa)
Ncoa1Nuclear receptor coactivator. (1444 aa)
I79_002290Egl nine-like 1. (183 aa)
I79_001871Transcription factor Ovo-like 2. (213 aa)
Plcd1Phosphoinositide phospholipase C. (782 aa)
EomesEomesodermin-like. (446 aa)
Sp3Transcription factor Sp3. (338 aa)
Ncoa6Nuclear receptor coactivator 6. (1843 aa)
I79_007335DnaJ-like subfamily B member 6-B. (138 aa)
Gjb5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (271 aa)
I79_025625Polycystin-2. (318 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
I79_024483Polycystin-2. (192 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_024097Vascular cell adhesion protein 1. (225 aa)
I79_023578Cathepsin R; Belongs to the peptidase C1 family. (333 aa)
I79_023577Cathepsin R; Belongs to the peptidase C1 family. (333 aa)
I79_023549Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating. (137 aa)
I79_023275Zinc finger protein 420. (492 aa)
Krt8Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (488 aa)
NsdhlSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating. (208 aa)
Nfe2Transcription factor NF-E2 45 kDa subunit. (374 aa)
Epas1Endothelial PAS domain-containing protein 1. (878 aa)
Taf10Transcription initiation factor TFIID subunit 10. (125 aa)
Vcam1Vascular cell adhesion protein 1. (220 aa)
Spint1Kunitz-type protease inhibitor 1. (499 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
I79_020212DnaJ-like subfamily B member 6. (361 aa)
I79_019825Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (403 aa)
Gcm1Chorion-specific transcription factor GCMa. (436 aa)
Rtl1Retrotransposon-like protein 1. (634 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Trim28Transcription intermediary factor 1-beta. (535 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
TfebTranscription factor EB-like protein. (476 aa)
TtpalAlpha-tocopherol transfer protein-like. (343 aa)
I79_016918ETS domain-containing transcription factor ERF. (58 aa)
Rtl5Retrotransposon gag domain-containing protein 4. (197 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
I79_016362Vasohibin-2. (477 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
AdmProcalcitonin/adrenomedullin containing protein. (184 aa)
I79_016057Protocadherin-12. (745 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Ascl2Achaete-scute-like 2. (193 aa)
Cdkn1cCyclin-dependent kinase inhibitor 1C. (217 aa)
Tmed2Transmembrane emp24 domain-containing protein 2. (116 aa)
I79_015503Transcription factor HES-1. (92 aa)
I79_015356Heat shock factor protein 1. (524 aa)
Prdm1PR domain zinc finger protein 1. (825 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
Sp1Transcription factor Sp1. (778 aa)
I79_014629Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (369 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (616 aa)
E2f7Transcription factor E2F7. (900 aa)
Plk4Serine/threonine-protein kinase PLK4. (928 aa)
Syde1Rho GTPase-activating protein SYDE1. (736 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
Plcd3Phosphoinositide phospholipase C. (886 aa)
I79_011377Grainyhead-like protein 2-like. (522 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2412 aa)
I79_011258Sentrin-specific protease 2. (314 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
I79_010743Kunitz-type protease inhibitor 2. (161 aa)
I79_010700Transcription factor Sp3. (441 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
I79_009796Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
Plac1Placenta-specific protein 1. (173 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
Vash1Vasohibin-1. (373 aa)
I79_009443Steroid hormone receptor ERR2. (475 aa)
Birc6Baculoviral IAP repeat-containing protein 6. (3348 aa)
Snai1Zinc finger protein SNAI1-like protein. (264 aa)
I79_009066Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (426 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.