STRINGSTRING
Mc4r Mc4r Sorl1 Sorl1 I79_023937 I79_023937 Adrb2 Adrb2 I79_020576 I79_020576 I79_019878 I79_019878 Sct Sct I79_016547 I79_016547 PPARG PPARG Trpv4 Trpv4 Clic5 Clic5 I79_005524 I79_005524 I79_003212 I79_003212 Gpr39 Gpr39 I79_000977 I79_000977
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mc4rMelanocortin receptor 4. (332 aa)
Sorl1Sortilin-related receptor. (223 aa)
I79_023937Sortilin-related receptor. (88 aa)
Adrb2Beta-2 adrenergic receptor. (337 aa)
I79_020576Mitochondrial brown fat uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (267 aa)
I79_019878Sortilin. (1038 aa)
SctSecretin-like protein. (132 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Trpv4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
Clic5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (236 aa)
I79_005524Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
I79_003212G-protein coupled receptor 39. (151 aa)
Gpr39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (289 aa)
I79_000977Metalloendopeptidase OMA1, mitochondrial. (238 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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