STRINGSTRING
Mzb1 Mzb1 I79_014940 I79_014940 Mad2l2 Mad2l2 IL2 IL2 Il21 Il21 Xbp1 Xbp1 Slc15a4 Slc15a4 I79_012810 I79_012810 I79_013438 I79_013438 Mlh1 Mlh1 Paxip1 Paxip1 Hpx Hpx Trex1 Trex1 Exosc3 Exosc3 Foxp3 Foxp3 I79_024481 I79_024481 Kmt5b Kmt5b Traf2 Traf2 Supt6h Supt6h Tmbim6 Tmbim6 I79_021848 I79_021848 Tgfb1 Tgfb1 Stx4 Stx4 Il33 Il33 Pagr1 Pagr1 Il4r Il4r Clcf1 Clcf1 I79_017613 I79_017613 I79_016659 I79_016659 Tnf Tnf I79_016106 I79_016106 I79_012384 I79_012384 I79_015274 I79_015274 Stat6 Stat6 Foxp1 Foxp1 Shld1 Shld1 Tfrc Tfrc Bcl6 Bcl6 Atad5 Atad5 Phb2 Phb2 I79_002750 I79_002750 Cd28 Cd28 Traf6 Traf6 Tlr9 Tlr9 Tnfsf4 Tnfsf4 DNAJB9 DNAJB9 Tp53bp1 Tp53bp1 I79_004452 I79_004452 Msh2 Msh2 Tbx21 Tbx21 I79_005968 I79_005968 I79_006232 I79_006232 Parp3 Parp3 Cd40 Cd40 Rbp4 Rbp4 Cd86 Cd86 Il10 Il10 H671_3g9841 H671_3g9841 Pkn1 Pkn1 I79_008828 I79_008828 Cgas Cgas Hmces Hmces Aplf Aplf Ephb2 Ephb2 I79_015109 I79_015109 Phb Phb Nsd2 Nsd2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mzb1Proapoptotic caspase adapter protein. (184 aa)
I79_014940Prohibitin. (85 aa)
Mad2l2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
Il21Interleukin-21. (67 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
Slc15a4Solute carrier family 15 member 4. (455 aa)
I79_012810B-cell receptor CD22. (504 aa)
I79_013438Prohibitin. (132 aa)
Mlh1DNA mismatch repair protein Mlh1-like protein. (720 aa)
Paxip1PAX-interacting protein 1. (91 aa)
HpxHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (461 aa)
Trex1Three prime repair exonuclease 1. (320 aa)
Exosc3Exosome complex exonuclease RRP40. (102 aa)
Foxp3Forkhead box protein P3. (428 aa)
I79_024481Prohibitin. (274 aa)
Kmt5bHistone-lysine N-methyltransferase SUV420H1. (451 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1725 aa)
Tmbim6Bax inhibitor 1; Belongs to the BI1 family. (237 aa)
I79_021848Telomere-associated protein RIF1. (1602 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Stx4Syntaxin-4; Belongs to the syntaxin family. (298 aa)
Il33Interleukin-33. (217 aa)
Pagr1PAXIP1-associated protein 1. (251 aa)
Il4rInterleukin-4 receptor alpha chain. (835 aa)
Clcf1Cardiotrophin-like cytokine factor 1. (225 aa)
I79_017613DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa)
I79_016659Leukocyte antigen CD37; Belongs to the tetraspanin (TM4SF) family. (273 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016106Histone-lysine N-methyltransferase SUV420H2. (225 aa)
I79_012384Leukocyte common antigen. (962 aa)
I79_015274Bax inhibitor 1; Belongs to the BI1 family. (56 aa)
Stat6Signal transducer and activator of transcription. (844 aa)
Foxp1Forkhead box protein P1. (696 aa)
Shld1Uncharacterized protein C20orf196-like. (208 aa)
TfrcTransferrin receptor protein 1. (757 aa)
Bcl6B-cell lymphoma 6 protein-like. (707 aa)
Atad5ATPase family AAA domain-containing protein 5. (1335 aa)
Phb2Prohibitin-2. (396 aa)
I79_002750Tumor necrosis factor ligand superfamily member 13; Belongs to the tumor necrosis factor family. (73 aa)
Cd28T-cell-specific surface glycoprotein CD28. (100 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
Tlr9Toll-like receptor 9. (1239 aa)
Tnfsf4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (185 aa)
DNAJB9DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-ass [...] (222 aa)
Tp53bp1Tumor suppressor p53-binding protein 1. (1952 aa)
I79_004452Prohibitin. (131 aa)
Msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa)
Tbx21T-box transcription factor TBX21. (365 aa)
I79_005968CD40 ligand; Belongs to the tumor necrosis factor family. (219 aa)
I79_006232PAX-interacting protein 1. (79 aa)
Parp3Poly [ADP-ribose] polymerase. (527 aa)
Cd40Tumor necrosis factor receptor superfamily member 5. (118 aa)
Rbp4Retinol-binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (338 aa)
Cd86T-lymphocyte activation antigen CD86. (269 aa)
Il10Interleukin-10. (178 aa)
H671_3g9841Interleukin-27 receptor subunit alpha. (566 aa)
Pkn1Serine/threonine-protein kinase N1; Belongs to the G-protein coupled receptor 2 family. (1696 aa)
I79_008828Lymphotactin. (114 aa)
CgasUncharacterized protein C6orf150. (512 aa)
HmcesAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa)
AplfAprataxin and PNK-like factor. (511 aa)
Ephb2Ephrin type-B receptor 2. (1018 aa)
I79_015109Interleukin-6. (174 aa)
PhbProhibitin. (272 aa)
Nsd2Putative histone-lysine N-methyltransferase NSD2. (1344 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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