STRINGSTRING
I79_000238 I79_000238 Inpp5d Inpp5d I79_024370 I79_024370 Ctnnbip1 Ctnnbip1 I79_024909 I79_024909 I79_025002 I79_025002 I79_025142 I79_025142 I79_025387 I79_025387 I79_025481 I79_025481 I79_025719 I79_025719 Trib1 Trib1 Myc Myc FSHB FSHB Tcta Tcta I79_006495 I79_006495 Pik3r1 Pik3r1 Pias3 Pias3 I79_004475 I79_004475 Zfp36l1 Zfp36l1 I79_003375 I79_003375 Traf6 Traf6 Tal1 Tal1 Ifnb1 Ifnb1 Asxl2 Asxl2 Cdk6 Cdk6 I79_002219 I79_002219 Cd4 Cd4 I79_001200 I79_001200 Evi2b Evi2b I79_001046 I79_001046 I79_000368 I79_000368 Mitf Mitf Foxp1 Foxp1 Tob2 Tob2 Casp8 Casp8 Cul4a Cul4a Fgfr3 Fgfr3 I79_011789 I79_011789 Tfe3 Tfe3 Runx1 Runx1 Thoc5 Thoc5 Ninj1 Ninj1 Notch2 Notch2 Prxl2a Prxl2a Fadd Fadd I79_013004 I79_013004 Rb1 Rb1 I79_013410 I79_013410 Il23a Il23a I79_013556 I79_013556 Ppargc1b Ppargc1b I79_013650 I79_013650 I79_013659 I79_013659 Cd74 Cd74 I79_010693 I79_010693 C1qc C1qc Kitlg Kitlg Gata2 Gata2 Sfrp1 Sfrp1 I79_009953 I79_009953 Zbtb46 Zbtb46 Tnfsf11 Tnfsf11 Ikzf1 Ikzf1 Fos Fos Fstl3 Fstl3 Apc Apc Cldn18 Cldn18 IL12B IL12B Hoxa7 Hoxa7 Fbxw9 Fbxw9 Hax1 Hax1 CgPICR_020542 CgPICR_020542 Gsk3b Gsk3b Il34 Il34 I79_007336 I79_007336 Ctnnb1 Ctnnb1 Ocstamp Ocstamp I79_013771 I79_013771 Nedd9 Nedd9 Mafb Mafb I79_014474 I79_014474 Tmem178a Tmem178a I79_014943 I79_014943 I79_015223 I79_015223 Gpr137b Gpr137b I79_015356 I79_015356 I79_015453 I79_015453 I79_015454 I79_015454 I79_016051 I79_016051 Adipoq Adipoq I79_016244 I79_016244 Tnf Tnf I79_016597 I79_016597 Lif Lif Il17a Il17a Pla2g3 Pla2g3 Lyn Lyn I79_017561 I79_017561 I79_017833 I79_017833 Gpr68 Gpr68 I79_018047 I79_018047 Klf10 Klf10 I79_018785 I79_018785 I79_018885 I79_018885 CgPICR_003405 CgPICR_003405 I79_019107 I79_019107 Gpr137 Gpr137 Esrra Esrra Ccl5 Ccl5 Tgfb1 Tgfb1 I79_020506 I79_020506 I79_021556 I79_021556 I79_021561 I79_021561 Tnfaip6 Tnfaip6 Mtor Mtor Ripk1 Ripk1 Gfi1b Gfi1b I79_022515 I79_022515 I79_022663 I79_022663 Fes Fes I79_022988 I79_022988 Gpr55 Gpr55 Csf1 Csf1 I79_023475 I79_023475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000238Zinc finger protein ZFPM1. (744 aa)
Inpp5dPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (91 aa)
I79_024370Microphthalmia-associated transcription factor. (185 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_024909C-type lectin domain family 2 member E. (263 aa)
I79_025002Ubiquitin-associated and SH3 domain-containing protein B. (201 aa)
I79_025142Tight junction protein ZO-2. (464 aa)
I79_025387Krueppel-like factor 10. (314 aa)
I79_025481Tight junction protein ZO-2. (294 aa)
I79_025719Tight junction protein ZO-2. (190 aa)
Trib1Tribbles-like 1. (286 aa)
MycMyc proto-oncogene protein. (281 aa)
FSHBFollicle stimulating hormone beta-subunit protein. (129 aa)
TctaT-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (109 aa)
I79_006495Pentaxin. (175 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Pias3E3 SUMO-protein ligase PIAS3. (619 aa)
I79_004475Carbonic anhydrase 2. (220 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
I79_003375Interleukin-20. (147 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
Tal1T-cell acute lymphocytic leukemia protein 1-like. (329 aa)
Ifnb1Interferon beta. (182 aa)
Asxl2Putative Polycomb group protein ASXL2. (1421 aa)
Cdk6Cell division protein kinase 6. (273 aa)
I79_002219Neuroendocrine secretory protein 55. (295 aa)
Cd4T-cell surface glycoprotein CD4. (447 aa)
I79_001200Tescalcin. (210 aa)
Evi2bProtein EVI2B. (172 aa)
I79_001046Neurofibromin. (2164 aa)
I79_000368Microphthalmia-associated transcription factor. (106 aa)
MitfMicrophthalmia-associated transcription factor. (474 aa)
Foxp1Forkhead box protein P1. (696 aa)
Tob2Protein Tob2. (345 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Cul4aCullin-4A; Belongs to the cullin family. (582 aa)
Fgfr3Fibroblast growth factor receptor 3. (319 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Tfe3Transcription factor E3. (574 aa)
Runx1Runt-related transcription factor 1. (462 aa)
Thoc5THO complex subunit 5-like. (683 aa)
Ninj1Ninjurin-1. (102 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
Prxl2aUncharacterized protein C10orf58-like. (229 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
I79_013004F-box/WD repeat-containing protein 7. (709 aa)
Rb1Retinoblastoma-associated protein. (302 aa)
I79_013410Apoptotic chromatin condensation inducer in the nucleus. (1230 aa)
Il23aInterleukin-23 subunit alpha. (196 aa)
I79_013556Fibrillin-1. (2698 aa)
Ppargc1bPeroxisome proliferator-activated receptor gamma coactivator 1-beta. (843 aa)
I79_013650Peroxisome proliferator-activated receptor gamma coactivator 1-beta. (111 aa)
I79_013659Macrophage colony-stimulating factor 1 receptor. (595 aa)
Cd74H-2 class II histocompatibility antigen gamma chain. (329 aa)
I79_010693Type II inositol-3,4-bisphosphate 4-phosphatase. (491 aa)
C1qcComplement C1q subcomponent subunit C. (478 aa)
KitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_009953Transcription factor AP-1. (72 aa)
Zbtb46Zinc finger and BTB domain-containing protein 46. (439 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
Ikzf1DNA-binding protein Ikaros. (489 aa)
FosProto-oncogene protein c-fos. (381 aa)
Fstl3Follistatin-related protein 3. (147 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
Hoxa7Homeobox protein Hox-A7. (112 aa)
Fbxw9F-box/WD repeat-containing protein 9. (458 aa)
Hax1HCLS1-associated protein X-1. (105 aa)
CgPICR_020542Nucleoside diphosphate kinase. (152 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
Il34Interleukin-34. (201 aa)
I79_007336Tumor necrosis factor receptor superfamily member 11B. (323 aa)
Ctnnb1Catenin beta-1. (781 aa)
OcstampTransmembrane protein C20orf123-like. (519 aa)
I79_013771Calcitonin. (206 aa)
Nedd9Enhancer of filamentation 1. (830 aa)
MafbTranscription factor MafB. (317 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
Tmem178aTransmembrane protein 178. (177 aa)
I79_014943Transmembrane 7 superfamily member 4. (243 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
Gpr137bIntegral membrane protein GPR137B. (385 aa)
I79_015356Heat shock factor protein 1. (524 aa)
I79_015453C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
I79_015454C-C chemokine receptor 1-like protein 1; Belongs to the G-protein coupled receptor 1 family. (329 aa)
I79_016051Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (777 aa)
AdipoqAdiponectin. (248 aa)
I79_016244Leucine-rich repeat-containing protein 17. (342 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016597Krueppel-like factor 10. (439 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
Il17aInterleukin-17A. (158 aa)
Pla2g3Group 3 secretory phospholipase A2. (398 aa)
LynTyrosine-protein kinase. (289 aa)
I79_017561Tyrosine-protein kinase Lyn. (101 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Gpr68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
I79_018047Krueppel-like factor 10. (94 aa)
Klf10Krueppel-like factor 10. (212 aa)
I79_018785Retinoic acid receptor alpha. (484 aa)
I79_018885Transmembrane protein 64. (105 aa)
CgPICR_003405C-C motif chemokine. (98 aa)
I79_019107Integral membrane protein GPR137C. (89 aa)
Gpr137Integral membrane protein GPR137. (265 aa)
EsrraSteroid hormone receptor ERR1. (548 aa)
Ccl5C-C motif chemokine. (91 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020506POU domain, class 4, transcription factor 2. (207 aa)
I79_021556C-type lectin domain family 2 member D11. (210 aa)
I79_021561C-type lectin domain family 2 member D11. (262 aa)
Tnfaip6Tumor necrosis factor-inducible gene 6 protein. (275 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (655 aa)
Gfi1bZinc finger protein Gfi-1b. (330 aa)
I79_022515Serine/threonine-protein phosphatase. (325 aa)
I79_022663Ubiquitin-associated and SH3 domain-containing protein B. (85 aa)
FesTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
I79_022988Mitochondrial sodium/hydrogen exchanger NHA2. (494 aa)
Gpr55Putative G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (332 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
I79_023475Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform. (81 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.