STRINGSTRING
Npm3 Npm3 Smarca4 Smarca4 I79_006254 I79_006254 I79_006745 I79_006745 Smad6 Smad6 Ednra Ednra Tbx2 Tbx2 I79_007135 I79_007135 Mef2c Mef2c Nrp2 Nrp2 Tgfbr3 Tgfbr3 I79_009001 I79_009001 Npy1r Npy1r I79_019338 I79_019338 Hey2 Hey2 Rbpj Rbpj Six1 Six1 Pitx2 Pitx2 Folr1 Folr1 Fgfr2 Fgfr2 I79_009030 I79_009030 I79_009364 I79_009364 Crkl Crkl I79_009953 I79_009953 Robo1 Robo1 I79_010159 I79_010159 Thbs1 Thbs1 Cdc42 Cdc42 I79_010748 I79_010748 I79_010749 I79_010749 Nipbl Nipbl Fzd1 Fzd1 Fzd2 Fzd2 I79_011943 I79_011943 Sema3c Sema3c I79_012060 I79_012060 Heyl Heyl I79_012727 I79_012727 Smad4 Smad4 Wnt11 Wnt11 Plxnd1 Plxnd1 I79_015033 I79_015033 Foxh1 Foxh1 I79_015503 I79_015503 I79_005573 I79_005573 Hif1a Hif1a Nrp1 Nrp1 Dicer1 Dicer1 Dvl3 Dvl3 Tbx20 Tbx20 I79_019149 I79_019149 Npy5r Npy5r Bmpr2 Bmpr2 Edn1 Edn1 Msx2 Msx2 Nog Nog Atf2 Atf2 Phf23 Phf23 Tgfbr2 Tgfbr2 Wnt5a Wnt5a I79_001239 I79_001239 Tbx3 Tbx3 Jag1 Jag1 I79_000238 I79_000238 I79_000157 I79_000157 I79_000092 I79_000092 ilk ilk Isl1 Isl1 Gja5 Gja5 I79_005566 I79_005566
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Tbx2T-box transcription factor TBX2. (234 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Nrp2Neuropilin; Belongs to the neuropilin family. (909 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
I79_009001Zinc finger protein ZFPM2. (718 aa)
Npy1rNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
I79_019338Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Six1Homeobox protein SIX1. (284 aa)
Pitx2Homeobox protein. (322 aa)
Folr1Folate receptor alpha. (257 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_009030T-box transcription factor TBX1. (293 aa)
I79_009364Transcription factor AP-2 alpha. (411 aa)
CrklCrk-like protein. (303 aa)
I79_009953Transcription factor AP-1. (72 aa)
Robo1Roundabout-like 1. (129 aa)
I79_010159Roundabout-like 1. (1362 aa)
Thbs1Thrombospondin-1. (533 aa)
Cdc42Cell division control protein 42-like. (191 aa)
I79_010748Ryanodine receptor 1. (1261 aa)
I79_010749Ryanodine receptor 1. (1965 aa)
NipblNipped-B-like protein. (104 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
I79_011943Semaphorin-3C. (86 aa)
Sema3cSemaphorin-3C; Belongs to the semaphorin family. (493 aa)
I79_012060Roundabout-like 2. (1397 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Plxnd1Plexin-D1. (612 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
Foxh1Forkhead box protein H1. (367 aa)
I79_015503Transcription factor HES-1. (92 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Dvl3Segment polarity protein dishevelled-like DVL-3. (503 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Edn1Endothelin-1. (202 aa)
Msx2Homeobox protein MSX-2. (267 aa)
NogNoggin. (117 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2. (487 aa)
Phf23Segment polarity protein dishevelled-like DVL-2. (697 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
I79_000238Zinc finger protein ZFPM1. (744 aa)
I79_000157E3 ubiquitin-protein ligase NEDD4. (1032 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
I79_005566Neuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (381 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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