STRINGSTRING
Gata3 Gata3 Ahr Ahr Smad4 Smad4 I79_014451 I79_014451 Wnt11 Wnt11 I79_020497 I79_020497 Ube4b Ube4b Hey2 Hey2 I79_021288 I79_021288 Rbpj Rbpj Dll4 Dll4 Sav1 Sav1 Rxra Rxra Pax8 Pax8 I79_022297 I79_022297 Pkp2 Pkp2 Trip11 Trip11 I79_023110 I79_023110 Ly6e Ly6e Pitx2 Pitx2 Fgfr2 Fgfr2 I79_024202 I79_024202 I79_024203 I79_024203 Matr3 Matr3 I79_015033 I79_015033 Prdm1 Prdm1 Foxh1 Foxh1 I79_015503 I79_015503 Cntrl Cntrl I79_015668 I79_015668 Sufu Sufu I79_016223 I79_016223 Hif1a Hif1a Frs2 Frs2 I79_025303 I79_025303 I79_025170 I79_025170 I79_024932 I79_024932 I79_024593 I79_024593 I79_024469 I79_024469 Rbm15 Rbm15 Pde2a Pde2a Gsk3a Gsk3a I79_017170 I79_017170 Tbx20 Tbx20 Npy5r Npy5r I79_019340 I79_019340 Ap2b1 Ap2b1 I79_009699 I79_009699 Robo1 Robo1 I79_010159 I79_010159 Acvr1 Acvr1 Bmp10 Bmp10 Luzp1 Luzp1 Ptcd2 Ptcd2 I79_010954 I79_010954 Tgfb1 Tgfb1 Cplane1 Cplane1 Nsd2 Nsd2 I79_011377 I79_011377 Fzd1 Fzd1 Fzd2 Fzd2 I79_011789 I79_011789 I79_011943 I79_011943 Sema3c Sema3c I79_012060 I79_012060 Heyl Heyl I79_012424 I79_012424 I79_012425 I79_012425 Ppp1r13l Ppp1r13l I79_012814 I79_012814 Nprl3 Nprl3 I79_012815 I79_012815 Chd7 Chd7 Smad7 Smad7 I79_013214 I79_013214 Aplnr Aplnr I79_013472 I79_013472 Myl3 Myl3 I79_009100 I79_009100 I79_009001 I79_009001 I79_008965 I79_008965 Fgfrl1 Fgfrl1 Tgfbr3 Tgfbr3 I79_008878 I79_008878 Dsp Dsp Nfatc1 Nfatc1 Zmpste24 Zmpste24 I79_007693 I79_007693 Smarcd3 Smarcd3 Greb1 Greb1 I79_007576 I79_007576 Mef2c Mef2c Myl10 Myl10 I79_007135 I79_007135 Ednra Ednra Smad6 Smad6 I79_006745 I79_006745 Vangl2 Vangl2 Tgfbr1 Tgfbr1 I79_006254 I79_006254 Fkbp1a Fkbp1a I79_005867 I79_005867 Smarca4 Smarca4 Med1 Med1 Sall1 Sall1 I79_005573 I79_005573 I79_005566 I79_005566 I79_005379 I79_005379 Hectd1 Hectd1 Tnnt2 Tnnt2 Tnni1 Tnni1 Gja5 Gja5 I79_004267 I79_004267 Isl1 Isl1 Nog Nog Cxcr4 Cxcr4 I79_003100 I79_003100 Bmpr2 Bmpr2 Mybpc3 Mybpc3 I79_002290 I79_002290 I79_001957 I79_001957 I79_001955 I79_001955 Tgfbr2 Tgfbr2 Wnt5a Wnt5a I79_001239 I79_001239 Tbx3 Tbx3 Tbx5 Tbx5 Heg1 Heg1 Jag1 Jag1 Foxf1 Foxf1 I79_000238 I79_000238 Prox1 Prox1 Kcnk2 Kcnk2 I79_000092 I79_000092
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
AhrAryl hydrocarbon receptor. (247 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
I79_014451Pro-neuregulin-1, membrane-bound isoform. (639 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
I79_020497Ubiquitin conjugation factor E4 B. (214 aa)
Ube4bUbiquitin conjugation factor E4 B. (385 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
I79_021288Transmembrane protein 65. (88 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
Sav1Protein salvador-like 1. (210 aa)
RxraRetinoic acid receptor RXR-alpha. (439 aa)
Pax8Paired box protein Pax-8. (452 aa)
I79_022297Plakophilin-2. (324 aa)
Pkp2Plakophilin-2. (429 aa)
Trip11Thyroid receptor-interacting protein 11. (1977 aa)
I79_023110Sal-like protein 4. (151 aa)
Ly6eLymphocyte antigen 6E. (130 aa)
Pitx2Homeobox protein. (322 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_024202Sal-like protein 1. (825 aa)
I79_024203Sal-like protein 1. (121 aa)
Matr3Matrin-3. (847 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
Prdm1PR domain zinc finger protein 1. (825 aa)
Foxh1Forkhead box protein H1. (367 aa)
I79_015503Transcription factor HES-1. (92 aa)
CntrlCentriolin. (1787 aa)
I79_015668Uncharacterized protein. (115 aa)
SufuSuppressor of fused-like. (266 aa)
I79_016223Tyrosine-protein kinase-like 7. (98 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Frs2Fibroblast growth factor receptor substrate 2. (509 aa)
I79_025303Myosin-6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1736 aa)
I79_025170Slit-like 2 protein. (345 aa)
I79_024932Dynactin subunit 5. (82 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_024469Sal-like protein 4. (1066 aa)
Rbm15Putative RNA-binding protein 15. (912 aa)
Pde2acGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
I79_017170Uncharacterized protein. (155 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
I79_019340Suppressor of fused-like. (144 aa)
Ap2b1AP-2 complex subunit beta. (490 aa)
I79_009699GREB1-like protein. (1598 aa)
Robo1Roundabout-like 1. (129 aa)
I79_010159Roundabout-like 1. (1362 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Bmp10Bone morphogenetic protein 10. (399 aa)
Luzp1Leucine zipper protein 1. (1066 aa)
Ptcd2Pentatricopeptide repeat-containing protein 2. (381 aa)
I79_010954Uncharacterized protein C5orf42. (531 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Cplane1Uncharacterized protein C5orf42. (563 aa)
Nsd2Putative histone-lysine N-methyltransferase NSD2. (1344 aa)
I79_011377Grainyhead-like protein 2-like. (522 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
I79_011943Semaphorin-3C. (86 aa)
Sema3cSemaphorin-3C; Belongs to the semaphorin family. (493 aa)
I79_012060Roundabout-like 2. (1397 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
I79_012424Ryanodine receptor 2. (2535 aa)
I79_012425Ryanodine receptor 2. (2233 aa)
Ppp1r13lRelA-associated inhibitor. (183 aa)
I79_012814Chromodomain-helicase-DNA-binding protein 7. (100 aa)
Nprl3UPF0171 protein C16orf35-like. (569 aa)
I79_012815Chromodomain-helicase-DNA-binding protein 7. (150 aa)
Chd7Chromodomain-helicase-DNA-binding protein 7. (615 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
I79_013214Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1929 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
I79_013472Nascent polypeptide-associated complex subunit alpha, muscle-specific form. (324 aa)
Myl3Myosin light chain 3. (200 aa)
I79_009100Latent-transforming growth factor beta-binding protein 1. (1194 aa)
I79_009001Zinc finger protein ZFPM2. (718 aa)
I79_008965Stimulated by retinoic acid gene 6 protein-like. (553 aa)
Fgfrl1Fibroblast growth factor receptor-like 1. (503 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
I79_008878Uncharacterized protein C20orf160. (327 aa)
DspDesmoplakin. (2836 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Smarcd3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (300 aa)
Greb1Protein GREB1. (1972 aa)
I79_007576Protein Mdm4. (405 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Myl10Myosin regulatory light chain 10-like protein. (190 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Vangl2Vang-like protein. (521 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Fkbp1aPeptidylprolyl isomerase. (79 aa)
I79_005867Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
Smarca4Putative global transcription activator SNF2L4. (1614 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Sall1Sal-like protein 1. (1294 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
I79_005566Neuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (381 aa)
I79_005379Tropomyosin alpha-1 chain; Belongs to the tropomyosin family. (158 aa)
Hectd1E3 ubiquitin-protein ligase HECTD1. (2610 aa)
Tnnt2Troponin T, cardiac muscle. (215 aa)
Tnni1Troponin I, slow skeletal muscle. (166 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
I79_004267Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (130 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
NogNoggin. (117 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
I79_003100Myocardin. (371 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Mybpc3Myosin-binding protein C, cardiac-type. (1374 aa)
I79_002290Egl nine-like 1. (183 aa)
I79_001957Slit-like 3 protein. (751 aa)
I79_001955Slit-like 3 protein. (566 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
Tbx5T-box transcription factor TBX5. (518 aa)
Heg1Protein HEG-like 1. (90 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Foxf1Forkhead box protein F1. (320 aa)
I79_000238Zinc finger protein ZFPM1. (744 aa)
Prox1Prospero homeobox protein 1. (738 aa)
Kcnk2Potassium channel subfamily K member 2. (215 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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