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Eif2b4 Eif2b4 Eif4a1 Eif4a1 EIF3M EIF3M I79_003561 I79_003561 Eif3j Eif3j Eif4e1b Eif4e1b Eif2s1 Eif2s1 Eif5 Eif5 I79_004690 I79_004690 EIF3G EIF3G Eif3a Eif3a EIF3I EIF3I I79_007120 I79_007120 I79_007119 I79_007119 Eif2s2 Eif2s2 EIF6 EIF6 I79_007550 I79_007550 Eif2d Eif2d Eif2b2 Eif2b2 Eif2a Eif2a I79_009709 I79_009709 Eif5b Eif5b DHX29 DHX29 I79_010278 I79_010278 I79_010751 I79_010751 Mtif2 Mtif2 I79_011623 I79_011623 H671_4g13040 H671_4g13040 Eif1 Eif1 Eif2s3 Eif2s3 I79_013096 I79_013096 CgPICR_011223 CgPICR_011223 Eif2b1 Eif2b1 Eif4a2 Eif4a2 I79_016148 I79_016148 Eif1ad Eif1ad Eif4g1 Eif4g1 Eif2b5 Eif2b5 Eif4g3 Eif4g3 EIF3F EIF3F I79_019049 I79_019049 I79_019512 I79_019512 I79_019915 I79_019915 I79_019918 I79_019918 I79_020539 I79_020539 I79_021191 I79_021191 Denr Denr H671_xg20331 H671_xg20331 I79_021958 I79_021958 Efhd1 Efhd1 Eif4b Eif4b EIF3C EIF3C Eif3e Eif3e I79_025107 I79_025107 Eif4e Eif4e EIF3D EIF3D I79_024071 I79_024071 Eif4e3 Eif4e3 Eif3b Eif3b Mtif3 Mtif3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Eif2b4Translation initiation factor eIF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (525 aa)
Eif4a1Eukaryotic initiation factor 4A-I; Belongs to the DEAD box helicase family. (359 aa)
EIF3MEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (374 aa)
I79_003561Eukaryotic translation initiation factor 3 subunit H. (294 aa)
Eif3jEukaryotic translation initiation factor 3 subunit J. (111 aa)
Eif4e1bEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (263 aa)
Eif2s1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
Eif5Eukaryotic translation initiation factor 5. (152 aa)
I79_004690Eukaryotic translation initiation factor 5. (108 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
Eif3aEukaryotic translation initiation factor 3 subunit A. (229 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
I79_007120Eukaryotic translation initiation factor 4B. (175 aa)
I79_007119Eukaryotic translation initiation factor 4B. (162 aa)
Eif2s2Eukaryotic translation initiation factor 2 subunit 2-like protein. (333 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
I79_007550Eukaryotic translation initiation factor 3 subunit E; Belongs to the eIF-3 subunit E family. (263 aa)
Eif2dLigatin. (590 aa)
Eif2b2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (257 aa)
Eif2aEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (582 aa)
I79_009709Eukaryotic translation initiation factor 2 subunit 2. (96 aa)
Eif5bEukaryotic translation initiation factor 5B. (491 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1371 aa)
I79_010278Eukaryotic translation initiation factor 1. (73 aa)
I79_010751Eukaryotic translation initiation factor 3 subunit K. (174 aa)
Mtif2Translation initiation factor IF-2, mitochondrial. (727 aa)
I79_011623Eukaryotic translation initiation factor 4B. (164 aa)
H671_4g13040Eukaryotic translation initiation factor 4H-like protein. (222 aa)
Eif1Eukaryotic translation initiation factor 1. (113 aa)
Eif2s3Eukaryotic translation initiation factor 2 subunit 3. (472 aa)
I79_013096Eukaryotic translation initiation factor 1. (107 aa)
CgPICR_011223Eukaryotic translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
Eif2b1Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (223 aa)
Eif4a2Eukaryotic initiation factor 4A-II-like isoform 1; Belongs to the DEAD box helicase family. (407 aa)
I79_016148Eukaryotic translation initiation factor 4 gamma 2. (783 aa)
Eif1adPutative RNA-binding protein EIF1AD. (171 aa)
Eif4g1Eukaryotic translation initiation factor 4 gamma 1. (1590 aa)
Eif2b5Translation initiation factor eIF-2B subunit epsilon. (716 aa)
Eif4g3Eukaryotic translation initiation factor 4 gamma 3. (1578 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (260 aa)
I79_019049Eukaryotic translation initiation factor 3 subunit L. (159 aa)
I79_019512Eukaryotic translation initiation factor 3 subunit C; Belongs to the eIF-3 subunit C family. (201 aa)
I79_019915Eukaryotic translation initiation factor 1. (113 aa)
I79_019918Eukaryotic translation initiation factor 1. (101 aa)
I79_020539Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
I79_021191Density-regulated protein. (54 aa)
DenrDensity-regulated protein; Belongs to the DENR family. (152 aa)
H671_xg20331Eukaryotic translation initiation factor 4 gamma 1 isoform 1. (309 aa)
I79_021958Eukaryotic translation initiation factor 1. (113 aa)
Efhd1Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (364 aa)
Eif4bEukaryotic translation initiation factor 4B. (616 aa)
EIF3CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (732 aa)
Eif3eEukaryotic translation initiation factor 3 subunit E. (84 aa)
I79_025107Eukaryotic translation initiation factor 2 subunit 2. (257 aa)
Eif4eEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (493 aa)
I79_024071Eukaryotic translation initiation factor 1A. (134 aa)
Eif4e3Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family. (190 aa)
Eif3bEukaryotic translation initiation factor 3 subunit B. (62 aa)
Mtif3Translation initiation factor IF-3, mitochondrial. (270 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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