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| | I79_024249 | Poly [ADP-ribose] polymerase 9. (106 aa) |
| | Fbh1 | F-box only protein 18. (580 aa) |
| | Gins2 | DNA replication complex GINS protein PSF2. (97 aa) |
| | I79_000259 | DNA replication complex GINS protein PSF2. (61 aa) |
| | Mcm8 | DNA replication licensing factor MCM8; Belongs to the MCM family. (833 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (564 aa) |
| | I79_000636 | Transmembrane 4 L6 family member 19. (226 aa) |
| | Dtx3l | Protein deltex-3-like. (763 aa) |
| | I79_000675 | Poly [ADP-ribose] polymerase 9. (337 aa) |
| | I79_000917 | ATP-dependent DNA helicase Q5. (467 aa) |
| | Lig4 | DNA ligase. (912 aa) |
| | Lig3 | DNA ligase. (1014 aa) |
| | Rad51d | DNA repair protein RAD51-like 4. (329 aa) |
| | I79_001367 | RAD51-associated protein 1. (336 aa) |
| | Iffo1 | Intermediate filament family orphan 1; Belongs to the intermediate filament family. (563 aa) |
| | Actr8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | Ercc8 | DNA excision repair protein ERCC-8. (397 aa) |
| | Ap5z1 | Uncharacterized protein KIAA0415. (769 aa) |
| | Top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1004 aa) |
| | I79_002013 | BRCA1-A complex subunit BRE. (288 aa) |
| | Rmi2 | RecQ-mediated genome instability protein 2. (52 aa) |
| | Ercc4 | DNA repair endonuclease XPF. (585 aa) |
| | Hus1b | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | I79_002347 | Fanconi anemia group D2 protein-like. (261 aa) |
| | Fancd2 | Fanconi anemia group D2 protein-like. (1068 aa) |
| | Samhd1 | SAM domain and HD domain-containing protein 1. (670 aa) |
| | I79_002649 | Actin-related protein 5; Belongs to the actin family. (269 aa) |
| | Rad54l | DNA repair and recombination protein RAD54-like. (306 aa) |
| | I79_003393 | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (432 aa) |
| | I79_003557 | Double-strand-break repair protein rad21-like. (687 aa) |
| | Tp53bp1 | Tumor suppressor p53-binding protein 1. (1952 aa) |
| | Uimc1 | BRCA1-A complex subunit RAP80. (722 aa) |
| | Rad51b | DNA repair protein RAD51-like 2. (153 aa) |
| | I79_004063 | DNA repair protein RAD51-like 2. (116 aa) |
| | Zfyve26 | Zinc finger FYVE domain-containing protein 26. (2385 aa) |
| | Exd2 | Exonuclease 3'-5' domain-containing protein 2. (496 aa) |
| | I79_004195 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (501 aa) |
| | Rpa2 | Replication protein A 32 kDa subunit. (248 aa) |
| | I79_004650 | Histone-lysine N-methyltransferase SETMAR. (312 aa) |
| | Xrcc3 | DNA repair protein XRCC3. (198 aa) |
| | I79_004699 | DNA repair protein XRCC3. (215 aa) |
| | Mta1 | Metastasis-associated protein MTA1. (697 aa) |
| | Mfsd11 | UNC93-like protein MFSD11. (446 aa) |
| | Smarcad1 | annotation not available (1016 aa) |
| | Epc1 | Enhancer of polycomb-like 1. (173 aa) |
| | I79_004955 | Nuclear ubiquitous casein and cyclin-dependent kinases substrate. (173 aa) |
| | Xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | Smarcal1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (916 aa) |
| | Ap5s1 | AP5S1. (200 aa) |
| | I79_005150 | Ankyrin repeat and LEM domain-containing protein 1. (469 aa) |
| | I79_005151 | BRCA1-A complex subunit MERIT40. (362 aa) |
| | Msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa) |
| | Wrn | Werner syndrome ATP-dependent helicase-like. (1405 aa) |
| | Swsap1 | Uncharacterized protein C19orf39-like. (281 aa) |
| | I79_006356 | DNA ligase 1; Belongs to the ATP-dependent DNA ligase family. (636 aa) |
| | Mcm2 | DNA helicase; Belongs to the MCM family. (905 aa) |
| | Rad52 | DNA repair protein RAD52-like. (419 aa) |
| | Parp3 | Poly [ADP-ribose] polymerase. (527 aa) |
| | I79_007343 | DNA2-like helicase. (134 aa) |
| | Dna2 | DNA2-like helicase. (767 aa) |
| | Polq | DNA polymerase theta. (2534 aa) |
| | I79_007758 | MBT domain-containing protein 1. (169 aa) |
| | Mbtd1 | MBT domain-containing protein 1. (469 aa) |
| | Eme1 | Crossover junction endonuclease EME1. (249 aa) |
| | Tdp1 | Tyrosyl-DNA phosphodiesterase 1. (609 aa) |
| | Eme2 | Putative crossover junction endonuclease EME2. (377 aa) |
| | Ints3 | Integrator complex subunit 3. (1041 aa) |
| | Chek2 | Serine/threonine-protein kinase Chk2. (539 aa) |
| | Slfnl1 | Schlafen-like protein 1. (395 aa) |
| | CUNH19orf57 | Uncharacterized protein C19orf57-like. (616 aa) |
| | I79_008544 | Meiotic recombination protein REC8-like. (451 aa) |
| | Cdc45 | CDC45-related protein. (282 aa) |
| | I79_009344 | ATP-dependent RNA helicase DDX1. (584 aa) |
| | Marf1 | Limkain-b1. (1736 aa) |
| | I79_009416 | Serine-protein kinase ATM. (1640 aa) |
| | I79_009706 | Retinoblastoma-binding protein 8. (326 aa) |
| | I79_009767 | Structural maintenance of chromosomes protein 6. (818 aa) |
| | I79_009768 | Flap endonuclease GEN-like 1. (317 aa) |
| | Gen1 | Flap endonuclease GEN-like 1. (514 aa) |
| | Recql | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (648 aa) |
| | Fancb | Fanconi anemia group B protein-like. (512 aa) |
| | I79_009998 | Fanconi anemia group B protein-like. (53 aa) |
| | Polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | Gins4 | DNA replication complex GINS protein SLD5. (375 aa) |
| | Smc6 | Structural maintenance of chromosomes protein 6. (54 aa) |
| | I79_010245 | Structural maintenance of chromosomes protein 6. (141 aa) |
| | Hmces | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa) |
| | Aplf | Aprataxin and PNK-like factor. (511 aa) |
| | Rpa3 | Replication protein A subunit-like protein. (121 aa) |
| | Nipbl | Nipped-B-like protein. (104 aa) |
| | I79_011087 | DNA polymerase nu. (297 aa) |
| | I79_011207 | DNA repair protein XRCC4. (176 aa) |
| | Brca1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa) |
| | I79_011834 | Breast cancer type 2 susceptibility protein-like. (143 aa) |
| | Brca2 | Breast cancer type 2 susceptibility protein-like. (3008 aa) |
| | Polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (491 aa) |
| | I79_012043 | DNA polymerase zeta catalytic subunit. (2601 aa) |
| | I79_012144 | Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (2171 aa) |
| | I79_012327 | N-acetyltransferase ESCO2. (481 aa) |
| | I79_012607 | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (568 aa) |
| | H671_21027 | DNA excision repair protein ERCC-1. (111 aa) |
| | Inip | SOSS complex subunit C-like protein. (104 aa) |
| | I79_012727 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa) |
| | I79_012829 | Histone H2A; Belongs to the histone H2A family. (146 aa) |
| | Fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1012 aa) |
| | Dclre1b | 5' exonuclease Apollo-like protein. (527 aa) |
| | Wdr48 | WD repeat-containing protein 48. (665 aa) |
| | Tnks1bp1 | 182 kDa tankyrase-1-binding protein. (1693 aa) |
| | Nabp2 | SOSS complex subunit B1. (211 aa) |
| | Ube2n | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (169 aa) |
| | Kdm4d | Lysine-specific demethylase 4D. (324 aa) |
| | I79_013864 | Lysine-specific demethylase 4D. (160 aa) |
| | Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (705 aa) |
| | Rnf138 | E3 ubiquitin-protein ligase RNF138. (199 aa) |
| | Mlh1 | DNA mismatch repair protein Mlh1-like protein. (720 aa) |
| | I79_014323 | ATP-dependent DNA helicase Q5. (409 aa) |
| | CgPICR_020046 | MORC family CW-type zinc finger protein 2B. (1024 aa) |
| | Mad2l2 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) |
| | Uvrag | UV radiation resistance-associated gene protein. (596 aa) |
| | Mms22l | tRNA (guanine(26)-N(2))-dimethyltransferase. (576 aa) |
| | Parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa) |
| | Recql4 | ATP-dependent DNA helicase Q4. (561 aa) |
| | Tonsl | NF-kappa-B inhibitor-like protein 2. (1366 aa) |
| | I79_015395 | Replication protein A 30 kDa subunit. (333 aa) |
| | Hus1 | Checkpoint protein; Belongs to the HUS1 family. (281 aa) |
| | I79_016081 | DNA polymerase. (1016 aa) |
| | Rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | I79_016282 | DNA repair protein XRCC1. (460 aa) |
| | Xrcc2 | DNA repair protein XRCC2. (222 aa) |
| | I79_016307 | Lys-63-specific deubiquitinase BRCC36-like. (291 aa) |
| | I79_016662 | Coiled-coil domain-containing protein 155. (629 aa) |
| | Slx4 | Structure-specific endonuclease subunit SLX4. (1731 aa) |
| | I79_016810 | Serine-protein kinase ATM. (473 aa) |
| | Poln | DNA polymerase nu. (300 aa) |
| | Cdc7 | Cell division cycle 7-related protein kinase. (572 aa) |
| | Psmd14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | Mcm3 | DNA helicase; Belongs to the MCM family. (807 aa) |
| | I79_017320 | Poly [ADP-ribose] polymerase. (513 aa) |
| | I79_017532 | Sororin. (111 aa) |
| | Mus81 | Crossover junction endonuclease MUS81. (149 aa) |
| | Mcm4 | DNA helicase; Belongs to the MCM family. (862 aa) |
| | I79_017613 | DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa) |
| | Spidr | Uncharacterized protein KIAA0146. (595 aa) |
| | I79_017872 | RING finger and WD repeat domain-containing protein 3. (105 aa) |
| | Rfwd3 | RING finger and WD repeat domain-containing protein 3. (641 aa) |
| | I79_017948 | Ubiquitin-conjugating enzyme E2 variant 2. (65 aa) |
| | I79_018104 | DNA replication complex GINS protein PSF2. (188 aa) |
| | I79_018181 | Lysine-specific demethylase 2A. (122 aa) |
| | Kdm2a | Lysine-specific demethylase 2A. (977 aa) |
| | I79_018346 | Structure-specific endonuclease subunit SLX1. (93 aa) |
| | Ppp4c | Serine/threonine-protein phosphatase. (307 aa) |
| | Poll | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (568 aa) |
| | Mcm9 | DNA replication licensing factor MCM9; Belongs to the MCM family. (893 aa) |
| | Brip1 | Fanconi anemia group J protein-like. (1166 aa) |
| | Pnkp | Bifunctional polynucleotide phosphatase/kinase. (522 aa) |
| | Emilin2 | EMILIN-2. (2121 aa) |
| | Aptx | Aprataxin. (341 aa) |
| | Iffo2 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. (282 aa) |
| | I79_020056 | E3 ubiquitin-protein ligase RNF138. (247 aa) |
| | I79_020102 | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | Hsf2bp | Heat shock factor 2-binding protein. (299 aa) |
| | Rnf169 | RING finger protein 169. (537 aa) |
| | Mcm5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | Rmi1 | RecQ-mediated genome instability protein 1. (618 aa) |
| | CUNH14orf39 | Protein SIX6OS1. (115 aa) |
| | Nabp1 | SOSS complex subunit B2. (198 aa) |
| | I79_021301 | Poly [ADP-ribose] polymerase 9. (112 aa) |
| | Tspan5 | Tetraspanin. (872 aa) |
| | I79_021340 | Uncharacterized protein C8orf45-like. (305 aa) |
| | I79_021404 | Putative DNA helicase INO80 complex-like 1. (1058 aa) |
| | Dclre1a | DNA cross-link repair 1A protein. (1022 aa) |
| | Kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | Ercc5 | DNA repair protein complementing XP-G cells-like. (1028 aa) |
| | I79_021945 | Pre-mRNA-processing factor 19. (487 aa) |
| | Setx | Putative helicase senataxin. (443 aa) |
| | I79_022532 | Structural maintenance of chromosomes protein 5. (861 aa) |
| | Blm | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (464 aa) |
| | I79_022999 | Fanconi anemia group M protein-like. (152 aa) |
| | I79_023244 | Bloom syndrome protein-like. (721 aa) |
| | Cdca5 | Sororin. (248 aa) |
| | Xrcc6 | ATP-dependent DNA helicase 2 subunit 1. (608 aa) |
| | Slx1a | Structure-specific endonuclease subunit SLX1. (124 aa) |
| | Abraxas1 | Helicase POLQ-like. (940 aa) |
| | Nsmce1 | Non-structural maintenance of chromosomes element 1-like. (220 aa) |
| | I79_024437 | Enterin neuropeptides. (161 aa) |
| | I79_024691 | Poly [ADP-ribose] polymerase 9. (187 aa) |
| | Trip13 | Thyroid receptor-interacting protein 13; Belongs to the AAA ATPase family. (404 aa) |
| | Palb2 | Partner and localizer of BRCA2. (993 aa) |
| | I79_025001 | Lysine-specific demethylase 4D. (139 aa) |
| | I79_025058 | Uncharacterized protein C9orf142-like. (230 aa) |
| | Apbb1 | Amyloid beta A4 protein-binding family B member 1. (530 aa) |
| | I79_025305 | UPF0389 protein FAM162A. (213 aa) |
| | I79_025393 | Uncharacterized protein C10orf78-like. (362 aa) |
| | I79_025641 | BRCA1-A complex subunit Abraxas. (82 aa) |
| | Rpa1 | Replication protein A 70 kDa DNA-binding subunit. (209 aa) |
| | Smc5 | Structural maintenance of chromosomes protein 5. (80 aa) |
| | I79_025902 | DNA replication licensing factor MCM2. (182 aa) |
| | I79_026101 | E3 SUMO-protein ligase NSE2. (68 aa) |
