STRINGSTRING
Cacna1h Cacna1h Calm2 Calm2 Fgf13 Fgf13 I79_007364 I79_007364 I79_007363 I79_007363 Chrm2 Chrm2 I79_007135 I79_007135 Cav1 Cav1 Ctnna3 Ctnna3 Lck Lck Atp1a1 Atp1a1 I79_006562 I79_006562 Atp1a2 Atp1a2 I79_006462 I79_006462 MED4 MED4 Tacr2 Tacr2 Ghsr Ghsr I79_005566 I79_005566 Gucy1a1 Gucy1a1 I79_005451 I79_005451 Rgs2 Rgs2 Adora1 Adora1 Tnnt2 Tnnt2 Tnni1 Tnni1 F2r F2r Gja5 Gja5 I79_004283 I79_004283 Ptafr Ptafr Slc8a3 Slc8a3 Arg2 Arg2 Dbn1 Dbn1 Cav3 Cav3 Oxtr Oxtr Tacr1 Tacr1 Edn1 Edn1 Chrnb4 Chrnb4 Chrna3 Chrna3 Adra2b Adra2b Fkbp1b Fkbp1b I79_003100 I79_003100 Mybpc3 Mybpc3 I79_002707 I79_002707 Ucn Ucn Ghrl Ghrl Ptgs2 Ptgs2 I79_002195 I79_002195 Kcnma1 Kcnma1 I79_002099 I79_002099 I79_002035 I79_002035 Abat Abat Pde4d Pde4d Dock5 Dock5 Stc1 Stc1 I79_001488 I79_001488 CgPICR_018403 CgPICR_018403 Kcna1 Kcna1 H671_2g5863 H671_2g5863 Kcnj2 Kcnj2 Sstr2 Sstr2 Cttn Cttn Smad7 Smad7 I79_013214 I79_013214 I79_013215 I79_013215 I79_013440 I79_013440 Ankrd52 Ankrd52 Sri Sri I79_013721 I79_013721 I79_013771 I79_013771 Tbxa2r Tbxa2r CgPICR_017756 CgPICR_017756 Myl3 Myl3 Sphk1 Sphk1 Chga Chga I79_014629 I79_014629 Gper1 Gper1 I79_015668 I79_015668 I79_015685 I79_015685 I79_015904 I79_015904 Kcnq1 Kcnq1 I79_016153 I79_016153 I79_016154 I79_016154 Hdac4 Hdac4 Slc9a1 Slc9a1 Srf Srf I79_016311 I79_016311 Trpm4 Trpm4 I79_016797 I79_016797 Dmd Dmd Smtn Smtn I79_017432 I79_017432 Chrm3 Chrm3 CgPICR_015426 CgPICR_015426 I79_017791 I79_017791 Agrn Agrn Ehd3 Ehd3 Actn3 Actn3 I79_018847 I79_018847 Adra2a Adra2a I79_019510 I79_019510 I79_019511 I79_019511 I79_020009 I79_020009 Stpg4 Stpg4 I79_020258 I79_020258 Akap6 Akap6 Ccn2 Ccn2 I79_020786 I79_020786 Ptgs1 Ptgs1 Rnf207 Rnf207 I79_021595 I79_021595 Adrb2 Adrb2 I79_022161 I79_022161 I79_022297 I79_022297 Pkp2 Pkp2 Ank2 Ank2 Nppa Nppa I79_023668 I79_023668 I79_023773 I79_023773 I79_024406 I79_024406 I79_024941 I79_024941 I79_025018 I79_025018 Kit Kit Tacr3 Tacr3 I79_025396 I79_025396 Map2k1 Map2k1 Ormdl3 Ormdl3 I79_026275 I79_026275 I79_012425 I79_012425 I79_012424 I79_012424 Adra1a Adra1a Jup Jup Tnnc2 Tnnc2 Ada Ada Pde4b Pde4b I79_011402 I79_011402 I79_011367 I79_011367 Atp2b1 Atp2b1 Bin1 Bin1 I79_010942 I79_010942 Tnni3k Tnni3k Casq2 Casq2 Setd3 Setd3 Bmp10 Bmp10 Trpv4 Trpv4 I79_010073 I79_010073 H671_xg20748 H671_xg20748 Hcn4 Hcn4 I79_008884 I79_008884 Zc3h12a Zc3h12a Adra1b Adra1b Dsp Dsp I79_008310 I79_008310 I79_008250 I79_008250 Zdhhc21 Zdhhc21 Shc1 Shc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H. (2745 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (161 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (117 aa)
I79_007364Catenin alpha-3. (100 aa)
I79_007363Catenin alpha-1. (93 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (558 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Ctnna3Catenin alpha-3. (95 aa)
LckProto-oncogene tyrosine-protein kinase LCK. (158 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (773 aa)
I79_006562Voltage-dependent L-type calcium channel subunit alpha-1C. (1112 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha-2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1194 aa)
I79_006462cGMP-dependent protein kinase 1, beta isozyme; Belongs to the protein kinase superfamily. (227 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (104 aa)
Tacr2Substance-K receptor. (320 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
I79_005566Neuropeptide Y receptor type 2; Belongs to the G-protein coupled receptor 1 family. (381 aa)
Gucy1a1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
I79_005451Annexin. (676 aa)
Rgs2Regulator of G-protein signaling 2. (207 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Tnnt2Troponin T, cardiac muscle. (215 aa)
Tnni1Troponin I, slow skeletal muscle. (166 aa)
F2rProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (396 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
I79_004283Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (906 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Slc8a3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
Arg2Arginase. (305 aa)
Dbn1Drebrin. (597 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
OxtrOxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (353 aa)
Tacr1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
Edn1Endothelin-1. (202 aa)
Chrnb4Neuronal acetylcholine receptor subunit beta-4. (496 aa)
Chrna3Neuronal acetylcholine receptor subunit alpha-3. (500 aa)
Adra2bAlpha-2B adrenergic receptor. (449 aa)
Fkbp1bPeptidylprolyl isomerase. (143 aa)
I79_003100Myocardin. (371 aa)
Mybpc3Myosin-binding protein C, cardiac-type. (1374 aa)
I79_002707Ran guanine nucleotide release factor. (163 aa)
UcnUrocortin. (122 aa)
GhrlAppetite-regulating hormone. (100 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
I79_002195Calcium-activated potassium channel subunit alpha-1. (326 aa)
Kcnma1Uncharacterized protein. (462 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
I79_002035Alpha-2C adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (230 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
Pde4dPhosphodiesterase. (507 aa)
Dock5Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (1446 aa)
Stc1Stanniocalcin-1. (247 aa)
I79_001488Rho GTPase-activating protein 10-like. (439 aa)
CgPICR_018403Protein C10. (126 aa)
Kcna1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
H671_2g5863Trimeric intracellular cation channel type B-like protein. (176 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
Sstr2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CttnSrc substrate cortactin. (550 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
I79_013214Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1929 aa)
I79_013215Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1866 aa)
I79_013440Calcitonin gene-related peptide type 1 receptor. (426 aa)
Ankrd52Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C. (1091 aa)
SriSorcin. (117 aa)
I79_013721P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (360 aa)
I79_013771Calcitonin. (206 aa)
Tbxa2rThromboxane A2 receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
CgPICR_017756Calmodulin-like protein; Belongs to the calmodulin family. (98 aa)
Myl3Myosin light chain 3. (200 aa)
Sphk1Sphingosine kinase 1. (383 aa)
ChgaChromogranin-A. (434 aa)
I79_014629Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (369 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
I79_015668Uncharacterized protein. (115 aa)
I79_015685EF-hand domain-containing protein. (101 aa)
I79_015904Potassium voltage-gated channel subfamily KQT member 1. (216 aa)
Kcnq1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (308 aa)
I79_016153Protein MRVI1. (378 aa)
I79_016154Protein MRVI1. (479 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
SrfSerum response factor. (361 aa)
I79_016311PRKC apoptosis WT1 regulator protein. (214 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4. (315 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
DmdDystrophin. (617 aa)
SmtnSmoothelin. (70 aa)
I79_017432Smoothelin. (918 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (589 aa)
CgPICR_015426Ran guanine nucleotide release factor. (154 aa)
I79_017791A-kinase anchor protein 9. (3428 aa)
AgrnAgrin. (2036 aa)
Ehd3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
Actn3Alpha-actinin-3. (900 aa)
I79_018847Calmodulin; Belongs to the calmodulin family. (152 aa)
Adra2aAlpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
I79_019510Desmocollin-2. (370 aa)
I79_019511Desmocollin-2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (430 aa)
I79_020009Phosphodiesterase. (597 aa)
Stpg4Calmodulin; Belongs to the calmodulin family. (211 aa)
I79_020258Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1853 aa)
Akap6A-kinase anchor protein 6. (1368 aa)
Ccn2Connective tissue growth factor-like protein. (348 aa)
I79_020786Calmodulin; Belongs to the calmodulin family. (141 aa)
Ptgs1Prostaglandin G/H synthase 1. (589 aa)
Rnf207RING finger protein 207. (603 aa)
I79_021595Neuromedin-K receptor; Belongs to the G-protein coupled receptor 1 family. (231 aa)
Adrb2Beta-2 adrenergic receptor. (337 aa)
I79_022161Dystrophin. (655 aa)
I79_022297Plakophilin-2. (324 aa)
Pkp2Plakophilin-2. (429 aa)
Ank2Ankyrin-2. (3299 aa)
NppaAtrial natriuretic factor. (362 aa)
I79_023668A-kinase anchor protein 9. (79 aa)
I79_023773Nuclear receptor subfamily 4 group A member 1. (924 aa)
I79_024406A-kinase anchor protein 6. (211 aa)
I79_024941Calmodulin; Belongs to the calmodulin family. (149 aa)
I79_025018Ankyrin-2. (85 aa)
KitMast/stem cell growth factor receptor. (452 aa)
Tacr3Neuromedin-K receptor. (166 aa)
I79_025396Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A. (230 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
Ormdl3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
I79_026275A-kinase anchor protein 9. (62 aa)
I79_012425Ryanodine receptor 2. (2233 aa)
I79_012424Ryanodine receptor 2. (2535 aa)
Adra1aAlpha-1A adrenergic receptor. (465 aa)
JupJunction plakoglobin. (1148 aa)
Tnnc2Troponin C, skeletal muscle. (145 aa)
AdaAdenosine deaminase. (363 aa)
Pde4bPhosphodiesterase. (517 aa)
I79_011402Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B. (579 aa)
I79_011367Plasma membrane calcium-transporting ATPase 1. (327 aa)
Atp2b1Plasma membrane calcium-transporting ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (384 aa)
Bin1Myc box-dependent-interacting protein 1. (522 aa)
I79_010942Serine/threonine-protein kinase TNNI3K. (584 aa)
Tnni3kSerine/threonine-protein kinase TNNI3K. (101 aa)
Casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (382 aa)
Setd3Protein-histidine N-methyltransferase. (577 aa)
Bmp10Bone morphogenetic protein 10. (399 aa)
Trpv4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
H671_xg20748Angiotensin-converting enzyme. (644 aa)
Hcn4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1033 aa)
I79_008884Myosin light chain kinase 2, skeletal/cardiac muscle. (747 aa)
Zc3h12aRibonuclease ZC3H12A. (577 aa)
Adra1bAlpha-1B adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (291 aa)
DspDesmoplakin. (2836 aa)
I79_008310Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1939 aa)
I79_008250Endothelin-2. (137 aa)
Zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
Shc1SHC-transforming protein 1. (579 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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