(25 nodes) Regulation of epidermal growth factor-activated receptor activity network (Cricetulus griseus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	Psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
	Cblb	E3 ubiquitin-protein ligase CBL-B. (984 aa)
	I79_013004	F-box/WD repeat-containing protein 7. (709 aa)
	Psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	App	Amyloid beta A4 protein. (433 aa)
	Vps25	Vacuolar protein-sorting-associated protein 25. (176 aa)
	Ncf1	Neutrophil cytosol factor 1. (303 aa)
	Zgpat	Zinc finger CCCH-type with G patch domain-containing protein. (188 aa)
	Fbxw9	F-box/WD repeat-containing protein 9. (458 aa)
	Gprc5a	Retinoic acid-induced protein 3. (354 aa)
	Socs4	Suppressor of cytokine signaling 4. (435 aa)
	Adora1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	Areg	Amphiregulin. (230 aa)
	Chmp6	Charged multivesicular body protein 6. (176 aa)
	I79_001115	Amyloid-like protein 2. (682 aa)
	I79_023268	Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
	Errfi1	ERBB receptor feedback inhibitor 1. (460 aa)
	I79_021564	Pro-epidermal growth factor. (699 aa)
	Ereg	Proepiregulin. (162 aa)
	I79_021125	Epigen. (135 aa)
	Socs5	Suppressor of cytokine signaling 5. (530 aa)
	Adra2a	Alpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	Tgfa	Protransforming growth factor alpha. (211 aa)
	Zfyve28	Lateral signaling target protein 2-like. (908 aa)
	I79_016131	Charged multivesicular body protein 6. (186 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
App	I79_001115	G3HMG4	G3GTX5	Amyloid beta A4 protein.	Amyloid-like protein 2.	0.592
App	I79_023268	G3HMG4	G3IHH8	Amyloid beta A4 protein.	Disintegrin and metalloproteinase domain-containing protein 17.	0.462
App	Psen1	G3HMG4	G3HNF2	Amyloid beta A4 protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.971
App	Psen2	G3HMG4	G3HV76	Amyloid beta A4 protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.906
Areg	Cblb	G3IBU4	G3HRG2	Amphiregulin.	E3 ubiquitin-protein ligase CBL-B.	0.509
Areg	Ereg	G3IBU4	G3IBU3	Amphiregulin.	Proepiregulin.	0.985
Areg	I79_021125	G3IBU4	G3IBU2	Amphiregulin.	Epigen.	0.859
Areg	I79_021564	G3IBU4	G3ID03	Amphiregulin.	Pro-epidermal growth factor.	0.777
Areg	I79_023268	G3IBU4	G3IHH8	Amphiregulin.	Disintegrin and metalloproteinase domain-containing protein 17.	0.455
Areg	Tgfa	G3IBU4	G3I6E7	Amphiregulin.	Protransforming growth factor alpha.	0.732
Cblb	Areg	G3HRG2	G3IBU4	E3 ubiquitin-protein ligase CBL-B.	Amphiregulin.	0.509
Cblb	Ereg	G3HRG2	G3IBU3	E3 ubiquitin-protein ligase CBL-B.	Proepiregulin.	0.508
Cblb	I79_021125	G3HRG2	G3IBU2	E3 ubiquitin-protein ligase CBL-B.	Epigen.	0.551
Cblb	I79_021564	G3HRG2	G3ID03	E3 ubiquitin-protein ligase CBL-B.	Pro-epidermal growth factor.	0.669
Cblb	Tgfa	G3HRG2	G3I6E7	E3 ubiquitin-protein ligase CBL-B.	Protransforming growth factor alpha.	0.593
Chmp6	I79_016131	G3GX54	G3HYJ7	Charged multivesicular body protein 6.	Charged multivesicular body protein 6.	0.902
Chmp6	Vps25	G3GX54	G3HLY6	Charged multivesicular body protein 6.	Vacuolar protein-sorting-associated protein 25.	0.964
Ereg	Areg	G3IBU3	G3IBU4	Proepiregulin.	Amphiregulin.	0.985
Ereg	Cblb	G3IBU3	G3HRG2	Proepiregulin.	E3 ubiquitin-protein ligase CBL-B.	0.508
Ereg	I79_021125	G3IBU3	G3IBU2	Proepiregulin.	Epigen.	0.775