STRINGSTRING
Mta1 Mta1 Prox1 Prox1 Hcrtr2 Hcrtr2 I79_000801 I79_000801 Lyrm9 Lyrm9 Ndufa9 Ndufa9 Ncor1 Ncor1 I79_001744 I79_001744 Ppp1cb Ppp1cb Kcnma1 Kcnma1 I79_002195 I79_002195 Csnk1d Csnk1d Ghrh Ghrh Vamp2 Vamp2 Tp53 Tp53 Cry2 Cry2 Pax4 Pax4 Lep Lep I79_003549 I79_003549 Nr1d2 Nr1d2 Hvcn1 Hvcn1 Drd2 Drd2 I79_004403 I79_004403 Ciart Ciart Bhlhe40 Bhlhe40 Htr7 Htr7 Prokr2 Prokr2 Tph2 Tph2 Nrip1 Nrip1 Igf1 Igf1 Prf1 Prf1 Hnrnpu Hnrnpu Kdm5a Kdm5a Hdac1 Hdac1 I79_006923 I79_006923 I79_006924 I79_006924 Thrap3 Thrap3 I79_007328 I79_007328 I79_007329 I79_007329 I79_007350 I79_007350 Sirt1 Sirt1 Gsk3b Gsk3b Ahcy Ahcy Noct Noct Mc3r Mc3r Srd5a1 Srd5a1 Ddx5 Ddx5 Id1 Id1 I79_008941 I79_008941 Pml Pml Egr1 Egr1 I79_009585 I79_009585 H671_1g1863 H671_1g1863 Nudt12 Nudt12 I79_009953 I79_009953 Rai1 Rai1 I79_010155 I79_010155 I79_010208 I79_010208 Gpr176 Gpr176 Hdac2 Hdac2 Fbxl3 Fbxl3 Prokr1 Prokr1 Cartpt Cartpt Ngf Ngf Ngfr Ngfr I79_011076 I79_011076 I79_011170 I79_011170 CUNH3orf70 CUNH3orf70 Btbd9 Btbd9 Naglu Naglu I79_011789 I79_011789 Id3 Id3 Cry1 Cry1 I79_012722 I79_012722 Mat2a Mat2a I79_012903 I79_012903 Maged1 Maged1 H671_3g9857 H671_3g9857 Fas Fas Slc6a4 Slc6a4 Prmt5 Prmt5 Timeless Timeless Mybbp1a Mybbp1a I79_013817 I79_013817 Kcnd2 Kcnd2 Ahr Ahr Aanat Aanat I79_014474 I79_014474 Dyrk1a Dyrk1a I79_015041 I79_015041 I79_015073 I79_015073 Mtnr1a Mtnr1a Rpe65 Rpe65 Top1 Top1 Mettl3 Mettl3 Ppargc1a Ppargc1a Bhlhe41 Bhlhe41 H671_3g9558 H671_3g9558 Nfil3 Nfil3 Adipoq Adipoq Nr0b2 Nr0b2 Tnf Tnf CgPICR_005625 CgPICR_005625 I79_016597 I79_016597 Dbp Dbp Homer1 Homer1 I79_016952 I79_016952 I79_017006 I79_017006 Per2 Per2 Zfhx3 Zfhx3 Kcnh7 Kcnh7 I79_017784 I79_017784 H671_3g9316 H671_3g9316 I79_018047 I79_018047 Klf10 Klf10 Ppp1ca Ppp1ca I79_018181 I79_018181 Kdm2a Kdm2a CgPICR_009543 CgPICR_009543 Rbm4b Rbm4b Ep300 Ep300 I79_018586 I79_018586 Nr1d1 Nr1d1 Nfilz Nfilz Kmt2a Kmt2a Hnf1b Hnf1b Lgr4 Lgr4 I79_019129 I79_019129 Atf5 Atf5 Hnrnpd Hnrnpd Nlgn3 Nlgn3 I79_019663 I79_019663 Ntrk2 Ntrk2 I79_019797 I79_019797 I79_019839 I79_019839 I79_020248 I79_020248 Clock Clock Hs3st2 Hs3st2 Dpyd Dpyd I79_021577 I79_021577 I79_021789 I79_021789 I79_021840 I79_021840 I79_021911 I79_021911 I79_022055 I79_022055 I79_022091 I79_022091 I79_022343 I79_022343 I79_022390 I79_022390 Ppara Ppara Setx Setx Tyms Tyms Rora Rora I79_022944 I79_022944 Atf4 Atf4 I79_023378 I79_023378 Ntrk3 Ntrk3 I79_023597 I79_023597 Usp2 Usp2 Prkg2 Prkg2 I79_023713 I79_023713 CgPICR_008504 CgPICR_008504 I79_024078 I79_024078 Gpr157 Gpr157 I79_024271 I79_024271 I79_024386 I79_024386 Tph1 Tph1 I79_024533 I79_024533 CgPICR_017245 CgPICR_017245 Ass1 Ass1 I79_025387 I79_025387 I79_025645 I79_025645 I79_025745 I79_025745 IMPDH2 IMPDH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mta1Metastasis-associated protein MTA1. (697 aa)
Prox1Prospero homeobox protein 1. (738 aa)
Hcrtr2Orexin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
I79_000801Histone deacetylase 1. (92 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
Ndufa9NmrA domain-containing protein. (377 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (299 aa)
Kcnma1Uncharacterized protein. (462 aa)
I79_002195Calcium-activated potassium channel subunit alpha-1. (326 aa)
Csnk1dCasein kinase I isoform delta. (358 aa)
GhrhSomatoliberin. (102 aa)
Vamp2Period circadian protein-like 1. (1281 aa)
Tp53Cellular tumor antigen p53. (148 aa)
Cry2Cryptochrome-2. (577 aa)
Pax4Paired box protein Pax-4. (231 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Nr1d2Nuclear receptor subfamily 1 group D member 2. (265 aa)
Hvcn1Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (511 aa)
Drd2D(2) dopamine receptor. (274 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
CiartUncharacterized protein C1orf51-like. (119 aa)
Bhlhe40Class E basic helix-loop-helix protein 40. (411 aa)
Htr75-hydroxytryptamine receptor 7. (391 aa)
Prokr2Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
Tph2Tryptophan 5-hydroxylase 2. (488 aa)
Nrip1Nuclear receptor-interacting protein 1. (1172 aa)
Igf1Insulin-like growth factor I. (75 aa)
Prf1Perforin-1. (555 aa)
HnrnpuHeterogeneous nuclear ribonucleoprotein U. (512 aa)
Kdm5aLysine-specific demethylase 5A. (1608 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
I79_006923Histone deacetylase 1. (235 aa)
I79_006924Histone deacetylase 1. (188 aa)
Thrap3Thyroid hormone receptor-associated protein 3. (307 aa)
I79_007328Histone deacetylase 2. (91 aa)
I79_007329Histone deacetylase 1. (250 aa)
I79_007350Protein atonal-like 7. (65 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
AhcyAdenosylhomocysteinase. (432 aa)
NoctNocturnin. (365 aa)
Mc3rMelanocortin receptor 3. (311 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
Ddx5Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (615 aa)
Id1DNA-binding protein inhibitor ID-1. (157 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
PmlPutative transcription factor PML. (540 aa)
Egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa)
I79_009585Tyrosine-protein kinase receptor. (727 aa)
H671_1g1863Aromatic-L-amino-acid decarboxylase-like protein. (447 aa)
Nudt12Peroxisomal NADH pyrophosphatase NUDT12. (462 aa)
I79_009953Transcription factor AP-1. (72 aa)
Rai1Retinoic acid-induced protein 1. (1764 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
I79_010208Putative G-protein coupled receptor 176. (84 aa)
Gpr176Putative G-protein coupled receptor 176. (327 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
Fbxl3Putative E3 ubiquitin-protein ligase MYCBP2. (4586 aa)
Prokr1Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family. (399 aa)
CartptCocaine-and amphetamine-regulated transcript protein. (112 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (429 aa)
I79_011076Coagulation factor X. (629 aa)
I79_011170BTB/POZ domain-containing protein 9. (247 aa)
CUNH3orf70UPF0524 protein C3orf70-like. (178 aa)
Btbd9BTB/POZ domain-containing protein 9. (385 aa)
NagluAlpha-N-acetylglucosaminidase. (740 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Id3DNA-binding protein inhibitor ID-3. (119 aa)
Cry1Cryptochrome-1. (428 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
Mat2aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (332 aa)
I79_012903Pulmonary surfactant-associated protein A. (238 aa)
Maged1Melanoma-associated antigen D1-like protein. (776 aa)
H671_3g9857Tumor necrosis factor receptor superfamily member 6-like protein. (170 aa)
FasTumor necrosis factor receptor superfamily member 6. (124 aa)
Slc6a4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (520 aa)
Prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (577 aa)
TimelessProtein timeless-like. (1200 aa)
Mybbp1aMyb-binding protein 1A. (932 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
Kcnd2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
AhrAryl hydrocarbon receptor. (247 aa)
AanatSerotonin N-acetyltransferase. (207 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
Dyrk1aDual specificity tyrosine-phosphorylation-regulated kinase 1A. (761 aa)
I79_015041Thymidylate synthase. (192 aa)
I79_015073Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (277 aa)
Mtnr1aMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (353 aa)
Rpe65Retinoid isomerohydrolase. (924 aa)
Top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (715 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Bhlhe41Class E basic helix-loop-helix protein 41. (165 aa)
H671_3g9558Tyrosine 3-monooxygenase-like protein. (542 aa)
Nfil3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (457 aa)
AdipoqAdiponectin. (248 aa)
Nr0b2Nuclear receptor subfamily 0 group B member 2. (260 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
CgPICR_005625Agouti-related protein. (131 aa)
I79_016597Krueppel-like factor 10. (439 aa)
DbpD site-binding protein. (123 aa)
Homer1Homer protein-like 1. (366 aa)
I79_016952Nicotinamide phosphoribosyltransferase. (401 aa)
I79_017006Aryl hydrocarbon receptor nuclear translocator-like protein 2. (391 aa)
Per2Period circadian protein-like 2. (1262 aa)
Zfhx3Zinc finger homeobox protein 3. (2785 aa)
Kcnh7Potassium voltage-gated channel subfamily H member 7. (689 aa)
I79_017784Dihydropyrimidine dehydrogenase [NADP+]. (519 aa)
H671_3g9316Adenosylhomocysteinase. (328 aa)
I79_018047Krueppel-like factor 10. (94 aa)
Klf10Krueppel-like factor 10. (212 aa)
Ppp1caSerine/threonine-protein phosphatase PP1-alpha catalytic subunit. (148 aa)
I79_018181Lysine-specific demethylase 2A. (122 aa)
Kdm2aLysine-specific demethylase 2A. (977 aa)
CgPICR_009543RNA-binding protein 4. (360 aa)
Rbm4bRNA-binding protein 4B. (357 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
NfilzNuclear factor interleukin-3-regulated protein. (278 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3512 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
I79_019129Sulfotransferase; Belongs to the sulfotransferase 1 family. (209 aa)
Atf5Cyclic AMP-dependent transcription factor ATF-5. (279 aa)
HnrnpdHeterogeneous nuclear ribonucleoprotein D0. (257 aa)
Nlgn3Neuroligin-3. (828 aa)
I79_01966325-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (216 aa)
Ntrk2Tyrosine-protein kinase receptor. (383 aa)
I79_019797BDNF/NT-3 growth factors receptor. (192 aa)
I79_019839Nuclear receptor coactivator. (1413 aa)
I79_020248Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (231 aa)
ClockCircadian locomoter output cycles protein kaput. (599 aa)
Hs3st2Sulfotransferase; Belongs to the sulfotransferase 1 family. (203 aa)
DpydDihydropyrimidine dehydrogenase [NADP+]. (74 aa)
I79_021577Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (248 aa)
I79_021789NT-3 growth factor receptor. (389 aa)
I79_021840Nuclear receptor ROR-gamma. (341 aa)
I79_021911Casein kinase I isoform epsilon. (370 aa)
I79_022055Argininosuccinate synthase. (97 aa)
I79_022091Protein kinase C delta-binding protein. (268 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
SetxPutative helicase senataxin. (443 aa)
TymsThymidylate synthase-like protein. (307 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
I79_022944Mitogen-activated protein kinase. (343 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (348 aa)
I79_023378Sulfotransferase; Belongs to the sulfotransferase 1 family. (119 aa)
Ntrk3Tyrosine-protein kinase receptor. (226 aa)
I79_023597Ubiquitin carboxyl-terminal hydrolase 2. (306 aa)
Usp2Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family. (379 aa)
Prkg2cGMP-dependent protein kinase 2. (546 aa)
I79_023713Dihydropyrimidine dehydrogenase [NADP+]. (120 aa)
CgPICR_008504Serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like protein. (326 aa)
I79_024078Period circadian protein-like 3. (949 aa)
Gpr157Putative G-protein coupled receptor 157. (253 aa)
I79_024271NT-3 growth factor receptor. (114 aa)
I79_024386JmjC domain-containing protein 5. (455 aa)
Tph1Tryptophan 5-hydroxylase 1. (115 aa)
I79_024533Tryptophan 5-hydroxylase 1. (131 aa)
CgPICR_017245Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
Ass1Argininosuccinate synthase. (242 aa)
I79_025387Krueppel-like factor 10. (314 aa)
I79_025645Cone-rod homeobox protein. (95 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. Belongs to the IMPDH/GMPR family. (514 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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