(11 nodes) Axon guidance receptor activity network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ephb2	Ephrin type-B receptor 2. (1018 aa)
	I79_010159	Roundabout-like 1. (1362 aa)
	Robo1	Roundabout-like 1. (129 aa)
	I79_000700	Receptor protein-tyrosine kinase. (871 aa)
	Ephb1	Ephrin type-B receptor 1. (737 aa)
	Sema5a	Semaphorin-5A. (1046 aa)
	I79_004732	Palladin. (379 aa)
	Ephb3	Ephrin type-B receptor 3. (930 aa)
	I79_004731	Palladin. (311 aa)
	L1cam	Neural cell adhesion molecule L1. (1287 aa)
	I79_012060	Roundabout-like 2. (1397 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ephb1	Ephb2	G3HD26	G3HIN4	Ephrin type-B receptor 1.	Ephrin type-B receptor 2.	0.920
Ephb1	Ephb3	G3HD26	G3I8W3	Ephrin type-B receptor 1.	Ephrin type-B receptor 3.	0.926
Ephb1	L1cam	G3HD26	G3HSW5	Ephrin type-B receptor 1.	Neural cell adhesion molecule L1.	0.628
Ephb2	Ephb1	G3HIN4	G3HD26	Ephrin type-B receptor 2.	Ephrin type-B receptor 1.	0.920
Ephb2	Ephb3	G3HIN4	G3I8W3	Ephrin type-B receptor 2.	Ephrin type-B receptor 3.	0.925
Ephb2	L1cam	G3HIN4	G3HSW5	Ephrin type-B receptor 2.	Neural cell adhesion molecule L1.	0.628
Ephb3	Ephb1	G3I8W3	G3HD26	Ephrin type-B receptor 3.	Ephrin type-B receptor 1.	0.926
Ephb3	Ephb2	G3I8W3	G3HIN4	Ephrin type-B receptor 3.	Ephrin type-B receptor 2.	0.925
I79_004731	I79_004732	G3H3B6	G3H3B7	Palladin.	Palladin.	0.899
I79_004732	I79_004731	G3H3B7	G3H3B6	Palladin.	Palladin.	0.899
I79_010159	Robo1	G3HHQ3	G3HHQ2	Roundabout-like 1.	Roundabout-like 1.	0.899
I79_012060	Robo1	G3HMT6	G3HHQ2	Roundabout-like 2.	Roundabout-like 1.	0.916
L1cam	Ephb1	G3HSW5	G3HD26	Neural cell adhesion molecule L1.	Ephrin type-B receptor 1.	0.628
L1cam	Ephb2	G3HSW5	G3HIN4	Neural cell adhesion molecule L1.	Ephrin type-B receptor 2.	0.628
Robo1	I79_010159	G3HHQ2	G3HHQ3	Roundabout-like 1.	Roundabout-like 1.	0.899
Robo1	I79_012060	G3HHQ2	G3HMT6	Roundabout-like 1.	Roundabout-like 2.	0.916