STRINGSTRING
CUNH9orf116 CUNH9orf116 I79_012378 I79_012378 Mapk9 Mapk9 Ercc2 Ercc2 I79_012652 I79_012652 H671_21027 H671_21027 Tp53i13 Tp53i13 Map2k7 Map2k7 I79_013706 I79_013706 I79_013707 I79_013707 Opn5 Opn5 Ddias Ddias Ro60 Ro60 Sde2 Sde2 Parp1 Parp1 Usp47 Usp47 Mettl3 Mettl3 I79_015813 I79_015813 Dhx36 Dhx36 Hus1 Hus1 I79_016104 I79_016104 N4bp1 N4bp1 Cul4b Cul4b I79_016412 I79_016412 Mapk13 Mapk13 I79_016638 I79_016638 I79_016646 I79_016646 I79_016692 I79_016692 Tipin Tipin I79_017305 I79_017305 Sdf4 Sdf4 Ep300 Ep300 Dtl Dtl Men1 Men1 CgPICR_011305 CgPICR_011305 I79_019171 I79_019171 Triap1 Triap1 Pold1 Pold1 Chek1 Chek1 Ei24 Ei24 I79_019845 I79_019845 I79_019899 I79_019899 I79_020089 I79_020089 Pold3 Pold3 Poli Poli I79_020497 I79_020497 Ube4b Ube4b I79_020548 I79_020548 Crip1 Crip1 Sirt1 Sirt1 Mmp9 Mmp9 Gpx1 Gpx1 Hyal2 Hyal2 I79_006285 I79_006285 I79_006201 I79_006201 Cdkn2d Cdkn2d Wrn Wrn Msh6 Msh6 Msh2 Msh2 Fech Fech Timp1 Timp1 I79_021404 I79_021404 I79_021699 I79_021699 Rela Rela Ercc5 Ercc5 Polk Polk I79_022455 I79_022455 Pclaf Pclaf Ddb1 Ddb1 Ivl Ivl Noc2l Noc2l I79_023875 I79_023875 I79_024061 I79_024061 I79_024437 I79_024437 Pbk Pbk Polh Polh I79_024790 I79_024790 Smpd1 Smpd1 I79_025438 I79_025438 Zbtb1 Zbtb1 Pik3r1 Pik3r1 I79_005238 I79_005238 Tmem161a Tmem161a Pcna Pcna Uaca Uaca Akt1 Akt1 Ube2b Ube2b Eif2s1 Eif2s1 Mmp2 Mmp2 Zranb3 Zranb3 Bak1 Bak1 Ccnd1 Ccnd1 I79_000157 I79_000157 Xpc Xpc RNF168 RNF168 Primpol Primpol I79_000761 I79_000761 Rhno1 Rhno1 Prkcd Prkcd Ccar2 Ccar2 Ercc8 Ercc8 Ercc4 Ercc4 Ptgs2 Ptgs2 Sprtn Sprtn I79_002649 I79_002649 I79_002881 I79_002881 Cat Cat Opn1sw Opn1sw I79_003202 I79_003202 Usp1 Usp1 I79_008527 I79_008527 IL12B IL12B I79_008941 I79_008941 Pml Pml Elane Elane Stk11 Stk11 Cirbp Cirbp I79_009795 I79_009795 Prkaa1 Prkaa1 I79_010114 I79_010114 Rev1 Rev1 Bmf Bmf I79_010207 I79_010207 Tp53inp1 Tp53inp1 Kdm1a Kdm1a Aqp1 Aqp1 Uvssa Uvssa Cdkn1a Cdkn1a Map3k2 Map3k2 Trex1 Trex1 I79_011284 I79_011284 Cdc25a Cdc25a I79_011834 I79_011834 Brca2 Brca2 I79_011990 I79_011990 I79_012059 I79_012059 I79_012163 I79_012163
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUNH9orf116UPF0691 protein C9orf116. (136 aa)
I79_012378Ubiquitin carboxyl-terminal hydrolase 1. (200 aa)
Mapk9Mitogen-activated protein kinase 9. (303 aa)
Ercc2TFIIH basal transcription factor complex helicase subunit. (141 aa)
I79_012652TFIIH basal transcription factor complex helicase subunit. (108 aa)
H671_21027DNA excision repair protein ERCC-1. (111 aa)
Tp53i13Tumor protein p53-inducible protein 13. (227 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7. (391 aa)
I79_013706CREB-binding protein. (759 aa)
I79_013707CREB-binding protein. (202 aa)
Opn5Opsin-5; Belongs to the G-protein coupled receptor 1 family. (258 aa)
DdiasNitric oxide-inducible gene protein. (902 aa)
Ro6060 kDa SS-A/Ro ribonucleoprotein. (503 aa)
Sde2UPF0667 protein C1orf55-like. (439 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa)
Usp47Ubiquitin carboxyl-terminal hydrolase 47. (754 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
I79_015813DNA polymerase kappa. (231 aa)
Dhx36Putative ATP-dependent RNA helicase DHX36. (922 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (281 aa)
I79_016104BR serine/threonine-protein kinase 1. (410 aa)
N4bp1NEDD4-binding protein 1. (811 aa)
Cul4bCullin-4B; Belongs to the cullin family. (834 aa)
I79_016412Mitogen-activated protein kinase kinase kinase kinase 5. (1079 aa)
Mapk13Mitogen-activated protein kinase. (278 aa)
I79_016638Protein phosphatase 1 regulatory subunit 15A. (445 aa)
I79_016646RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (518 aa)
I79_016692CREB-binding protein. (1054 aa)
TipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (243 aa)
I79_017305Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Sdf445 kDa calcium-binding protein. (355 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
DtlDenticleless protein-like. (667 aa)
Men1Menin. (610 aa)
CgPICR_011305E3 ubiquitin-protein ligase RAD18. (72 aa)
I79_019171E3 ubiquitin-protein ligase RAD18. (252 aa)
Triap1TP53-regulated inhibitor of apoptosis 1. (79 aa)
Pold1DNA polymerase. (1056 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
Ei24Etoposide-induced protein 2.4-like. (341 aa)
I79_019845Melanoma-associated antigen G1. (278 aa)
I79_019899E3 ubiquitin-protein ligase RAD18. (497 aa)
I79_020089Caspase-9; Belongs to the peptidase C14A family. (689 aa)
Pold3DNA polymerase delta subunit 3. (462 aa)
PoliDNA polymerase iota. (670 aa)
I79_020497Ubiquitin conjugation factor E4 B. (214 aa)
Ube4bUbiquitin conjugation factor E4 B. (385 aa)
I79_020548Receptor-type tyrosine-protein phosphatase kappa. (858 aa)
Crip1Cysteine-rich protein 1. (70 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Hyal2Hyaluronidase. (359 aa)
I79_006285DNA repair protein complementing XP-A cells-like. (231 aa)
I79_006201Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (77 aa)
Cdkn2dCyclin-dependent kinase 4 inhibitor D. (166 aa)
WrnWerner syndrome ATP-dependent helicase-like. (1405 aa)
Msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1260 aa)
Msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa)
FechFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (348 aa)
Timp1Metalloproteinase inhibitor 1-like protein. (203 aa)
I79_021404Putative DNA helicase INO80 complex-like 1. (1058 aa)
I79_021699Rhomboid domain-containing protein 1. (298 aa)
RelaTranscription factor p65. (546 aa)
Ercc5DNA repair protein complementing XP-G cells-like. (1028 aa)
PolkDNA polymerase kappa. (440 aa)
I79_022455Receptor-type tyrosine-protein phosphatase kappa. (375 aa)
PclafPCNA-associated factor. (111 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
IvlInvolucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. (406 aa)
Noc2lPutative nucleolar complex protein 2 like protein. (748 aa)
I79_023875Tripartite motif-containing protein 32. (265 aa)
I79_024061Ubiquitin carboxyl-terminal hydrolase 28; Belongs to the peptidase C19 family. (1027 aa)
I79_024437Enterin neuropeptides. (161 aa)
PbkLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
PolhDNA polymerase eta. (633 aa)
I79_024790Cysteine-rich protein 1. (77 aa)
Smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (593 aa)
I79_025438Uncharacterized protein C10orf90. (366 aa)
Zbtb1Zinc finger and BTB domain-containing protein 1. (713 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
I79_005238RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (193 aa)
Tmem161aTransmembrane protein 161A. (219 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
UacaUveal autoantigen with coiled-coil domains and ankyrin repeats. (1396 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Ube2bUbiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (119 aa)
Eif2s1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
Mmp272 kDa type IV collagenase. (662 aa)
Zranb3Zinc finger Ran-binding domain-containing protein 3. (723 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
I79_000157E3 ubiquitin-protein ligase NEDD4. (1032 aa)
XpcDNA repair protein complementing XP-C cells-like. (926 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (564 aa)
PrimpolCoiled-coil domain-containing protein 111. (288 aa)
I79_000761Non-specific serine/threonine protein kinase; Belongs to the PI3/PI4-kinase family. (1026 aa)
Rhno1Uncharacterized protein C12orf32-like. (245 aa)
PrkcdNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
Ccar2Protein KIAA1967-like. (916 aa)
Ercc8DNA excision repair protein ERCC-8. (397 aa)
Ercc4DNA repair endonuclease XPF. (585 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
SprtnZinc finger RAD18 domain-containing protein C1orf124-like. (502 aa)
I79_002649Actin-related protein 5; Belongs to the actin family. (269 aa)
I79_002881DNA damage-binding protein 2. (294 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
Opn1swShort-wave-sensitive opsin 1-like protein. (346 aa)
I79_003202Ubiquitin carboxyl-terminal hydrolase 1; Belongs to the peptidase C19 family. (303 aa)
Usp1Ubiquitin carboxyl-terminal hydrolase 1; Belongs to the peptidase C19 family. (419 aa)
I79_008527Nuclear factor of activated T-cells, cytoplasmic 4. (849 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
PmlPutative transcription factor PML. (540 aa)
ElaneNeutrophil elastase; Belongs to the peptidase S1 family. (252 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
CirbpCold-inducible RNA-binding protein. (184 aa)
I79_009795Mitogen-activated protein kinase kinase kinase 4. (1824 aa)
Prkaa1Non-specific serine/threonine protein kinase. (477 aa)
I79_010114DNA repair protein REV1. (463 aa)
Rev1DNA repair protein REV1. (701 aa)
BmfBcl-2-modifying factor. (199 aa)
I79_010207Eukaryotic translation initiation factor 2-alpha kinase 4. (1513 aa)
Tp53inp1Tumor protein p53-inducible nuclear protein 1. (239 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
UvssaUncharacterized protein KIAA1530. (700 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1. (163 aa)
Map3k2TFIIH basal transcription factor complex helicase XPB subunit. (1183 aa)
Trex1Three prime repair exonuclease 1. (320 aa)
I79_011284M-phase inducer phosphatase 1. (307 aa)
Cdc25aM-phase inducer phosphatase 1. (121 aa)
I79_011834Breast cancer type 2 susceptibility protein-like. (143 aa)
Brca2Breast cancer type 2 susceptibility protein-like. (3008 aa)
I79_011990Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (220 aa)
I79_012059Tripartite motif-containing protein 32. (556 aa)
I79_012163Etoposide-induced protein 2.4-like. (140 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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