STRINGSTRING
Hoxd4 Hoxd4 Dlx2 Dlx2 I79_003731 I79_003731 Gli2 Gli2 Tp63 Tp63 Dlx1 Dlx1 Aldh1a2 Aldh1a2 Grem1 Grem1 Irx1 Irx1 Irx2 Irx2 Pbx2 Pbx2 Gli1 Gli1 Gli3 Gli3 I79_014806 I79_014806 Hoxc10 Hoxc10 I79_013067 I79_013067 Dll1 Dll1 Pbx1 Pbx1 Apc Apc Wnt8a Wnt8a Osr1 Osr1 Hoxa11 Hoxa11 I79_008458 I79_008458 Hoxa9 Hoxa9 Ctnnb1 Ctnnb1 Nodal Nodal Chsy1 Chsy1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hoxd4Homeobox protein Hox-D10. (371 aa)
Dlx2Homeobox protein DLX-2. (347 aa)
I79_003731Iroquois-class homeodomain protein IRX-3. (341 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
Dlx1Homeobox protein DLX-1. (255 aa)
Aldh1a2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (460 aa)
Grem1Gremlin-1. (117 aa)
Irx1Iroquois-class homeodomain protein IRX-1. (319 aa)
Irx2Iroquois-class homeodomain protein IRX-2. (211 aa)
Pbx2Pre-B-cell leukemia transcription factor 2. (240 aa)
Gli1Zinc finger protein GLI1. (1104 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
I79_014806Homeobox protein Hox-C11. (229 aa)
Hoxc10Homeobox protein Hox-C10. (299 aa)
I79_013067Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (443 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
ApcAdenomatous polyposis coli protein. (2488 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (195 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
I79_008458Homeobox protein Hox-A10. (117 aa)
Hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (271 aa)
Ctnnb1Catenin beta-1. (781 aa)
NodalNodal. (309 aa)
Chsy1Hexosyltransferase. (203 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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