(32 nodes) Response to iron ion network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	Atp7a	Copper-transporting ATPase 1. (1457 aa)
	I79_013257	Cytoplasmic aconitate hydratase. (808 aa)
	Becn1	Beclin-1. (448 aa)
	I79_010620	Alpha-synuclein; Belongs to the synuclein family. (166 aa)
	Alad	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
	I79_009364	Transcription factor AP-2 alpha. (411 aa)
	Gpld1	Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
	Hfe	Hereditary hemochromatosis protein-like; Belongs to the MHC class I family. (306 aa)
	Bmp6	Bone morphogenetic protein 6. (296 aa)
	Map1lc3a	Microtubule-associated proteins 1A/1B light chain 3A. (278 aa)
	I79_004403	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
	Drd2	D(2) dopamine receptor. (274 aa)
	B2m	Beta-2-microglobulin. (54 aa)
	Lct	DNA helicase; Belongs to the MCM family. (2669 aa)
	Slc40a1	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (574 aa)
	Fxn	Frataxin, mitochondrial. (136 aa)
	I79_003225	Serotransferrin. (1227 aa)
	I79_025355	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (325 aa)
	Ccnd1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
	Tfrc	Transferrin receptor protein 1. (757 aa)
	I79_001265	Cytochrome b reductase 1. (284 aa)
	Abat	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
	Slc11a2	Natural resistance-associated macrophage protein 2. (474 aa)
	I79_021045	Heme oxygenase 1. (81 aa)
	Hmox1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
	I79_018978	Transferrin receptor protein 2. (290 aa)
	Cpox	Coproporphyrinogen-III oxidase, mitochondrial. (233 aa)
	Fn1	Fibronectin. (2486 aa)
	Hif1a	Hypoxia-inducible factor 1 alpha. (820 aa)
	I79_016240	Beclin-1. (119 aa)
	I79_015113	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (240 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (147 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abat	Alad	G3GVN2	G3HHZ9	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.680
Alad	Abat	G3HHZ9	G3GVN2	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.680
Alad	Cpox	G3HHZ9	G3I3V3	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Coproporphyrinogen-III oxidase, mitochondrial.	0.900
Alad	Fxn	G3HHZ9	G3IKA0	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Frataxin, mitochondrial.	0.413
Alad	Hmox1	G3HHZ9	G3IAI6	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.410
Alad	I79_021045	G3HHZ9	G3IBL9	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Heme oxygenase 1.	0.410
Atg5	Becn1	G3HVR2	G3HLZ1	Autophagy protein 5; Involved in autophagic vesicle formation.	Beclin-1.	0.955
Atg5	I79_010620	G3HVR2	G3HIY8	Autophagy protein 5; Involved in autophagic vesicle formation.	Alpha-synuclein; Belongs to the synuclein family.	0.411
Atg5	I79_016240	G3HVR2	G3HYU8	Autophagy protein 5; Involved in autophagic vesicle formation.	Beclin-1.	0.955
Atg5	Map1lc3a	G3HVR2	G3HAP1	Autophagy protein 5; Involved in autophagic vesicle formation.	Microtubule-associated proteins 1A/1B light chain 3A.	0.799
B2m	Hfe	G3H0S7	G3HDU0	Beta-2-microglobulin.	Hereditary hemochromatosis protein-like; Belongs to the MHC class I family.	0.916
B2m	Tfrc	G3H0S7	G3GSM5	Beta-2-microglobulin.	Transferrin receptor protein 1.	0.654
Becn1	Atg5	G3HLZ1	G3HVR2	Beclin-1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.955
Becn1	I79_010620	G3HLZ1	G3HIY8	Beclin-1.	Alpha-synuclein; Belongs to the synuclein family.	0.439
Becn1	Map1lc3a	G3HLZ1	G3HAP1	Beclin-1.	Microtubule-associated proteins 1A/1B light chain 3A.	0.673
Bmp6	Hfe	G3HD96	G3HDU0	Bone morphogenetic protein 6.	Hereditary hemochromatosis protein-like; Belongs to the MHC class I family.	0.644
Bmp6	I79_018978	G3HD96	G3I666	Bone morphogenetic protein 6.	Transferrin receptor protein 2.	0.562
Ccnd1	Hif1a	A5A422	G3HZ04	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Hypoxia-inducible factor 1 alpha.	0.600
Cpox	Alad	G3I3V3	G3HHZ9	Coproporphyrinogen-III oxidase, mitochondrial.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.900
Cpox	Hmox1	G3I3V3	G3IAI6	Coproporphyrinogen-III oxidase, mitochondrial.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.432