(19 nodes) Specification of animal organ identity network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	Gli3	Zinc finger protein GLI3. (1582 aa)
	Foxh1	Forkhead box protein H1. (367 aa)
	I79_017126	T-box brain protein 1. (74 aa)
	Tbr1	T-box brain protein 1. (231 aa)
	I79_021155	Paired box protein Pax-2. (503 aa)
	Rbpj	Recombining binding protein suppressor of hairless-like protein. (486 aa)
	Pax8	Paired box protein Pax-8. (452 aa)
	I79_024048	Paired box protein Pax-3. (324 aa)
	Fgfr2	Fibroblast growth factor receptor 2. (659 aa)
	I79_024314	Paired box protein Pax-3. (301 aa)
	Smarcd3	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (300 aa)
	Mef2c	Myocyte-specific enhancer factor 2C. (465 aa)
	Ext1	Exostosin-1. (388 aa)
	Axin2	Axin-2. (809 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	Isl1	Insulin gene enhancer protein ISL-1. (257 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	I79_001239	Low-density lipoprotein receptor-related protein 2. (4664 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Axin2	I79_001239	G3H862	G3GU85	Axin-2.	Low-density lipoprotein receptor-related protein 2.	0.485
Axin2	Wnt11	G3H862	G3HUR9	Axin-2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.563
Axin2	Wnt5a	G3H862	G3GUT6	Axin-2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.532
Foxh1	I79_017126	G3HWK9	G3I177	Forkhead box protein H1.	T-box brain protein 1.	0.414
Foxh1	Tbr1	G3HWK9	G3I178	Forkhead box protein H1.	T-box brain protein 1.	0.414
I79_001239	Axin2	G3GU85	G3H862	Low-density lipoprotein receptor-related protein 2.	Axin-2.	0.485
I79_001239	Wnt5a	G3GU85	G3GUT6	Low-density lipoprotein receptor-related protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.401
I79_006254	Isl1	G3H7C4	G3H207	Bone morphogenetic protein 4.	Insulin gene enhancer protein ISL-1.	0.532
I79_017126	Foxh1	G3I177	G3HWK9	T-box brain protein 1.	Forkhead box protein H1.	0.414
I79_024048	I79_024314	G3IJL2	G3IKB5	Paired box protein Pax-3.	Paired box protein Pax-3.	0.889
I79_024314	I79_024048	G3IKB5	G3IJL2	Paired box protein Pax-3.	Paired box protein Pax-3.	0.889
Isl1	I79_006254	G3H207	G3H7C4	Insulin gene enhancer protein ISL-1.	Bone morphogenetic protein 4.	0.532
Isl1	Mef2c	G3H207	G3HAW1	Insulin gene enhancer protein ISL-1.	Myocyte-specific enhancer factor 2C.	0.601
Mef2c	Isl1	G3HAW1	G3H207	Myocyte-specific enhancer factor 2C.	Insulin gene enhancer protein ISL-1.	0.601
Mef2c	Smarcd3	G3HAW1	G3HB60	Myocyte-specific enhancer factor 2C.	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3.	0.549
Smarcd3	Mef2c	G3HB60	G3HAW1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3.	Myocyte-specific enhancer factor 2C.	0.549
Tbr1	Foxh1	G3I178	G3HWK9	T-box brain protein 1.	Forkhead box protein H1.	0.414
Wnt11	Axin2	G3HUR9	G3H862	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin-2.	0.563
Wnt11	Wnt5a	G3HUR9	G3GUT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.557
Wnt5a	Axin2	G3GUT6	G3H862	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin-2.	0.532