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| | Snai2 | Zinc finger protein SNAI2-like protein. (268 aa) |
| | I79_017129 | TRAF family member-associated NF-kappa-B activator. (427 aa) |
| | I79_017613 | DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa) |
| | Spidr | Uncharacterized protein KIAA0146. (595 aa) |
| | Ikbip | Inhibitor of nuclear factor kappa-B kinase-interacting protein. (373 aa) |
| | I79_017872 | RING finger and WD repeat domain-containing protein 3. (105 aa) |
| | Rfwd3 | RING finger and WD repeat domain-containing protein 3. (641 aa) |
| | Hras | GTPase HRas-like protein. (189 aa) |
| | Rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (392 aa) |
| | Kars1 | Lysine--tRNA ligase. (626 aa) |
| | I79_018721 | Elongation factor 1-delta. (332 aa) |
| | Anxa1 | Annexin. (346 aa) |
| | I79_018795 | Integrator complex subunit 7. (108 aa) |
| | I79_018796 | Integrator complex subunit 7. (652 aa) |
| | Men1 | Menin. (610 aa) |
| | Krt14 | Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (483 aa) |
| | Bak1 | Bcl-2-likeous antagonist/killer. (209 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | Gata3 | Trans-acting T-cell-specific transcription factor GATA-3. (443 aa) |
| | Net1 | Neuroepithelial cell-transforming gene 1 protein. (540 aa) |
| | I79_000233 | Cytochrome b-245 light chain. (206 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (564 aa) |
| | I79_000761 | Non-specific serine/threonine protein kinase; Belongs to the PI3/PI4-kinase family. (1026 aa) |
| | CgPICR_012052 | Growth factor receptor-bound protein 2. (217 aa) |
| | Lig4 | DNA ligase. (912 aa) |
| | CgPICR_003438 | C-C motif chemokine. (143 aa) |
| | I79_001072 | C-C motif chemokine. (97 aa) |
| | I79_001239 | Low-density lipoprotein receptor-related protein 2. (4664 aa) |
| | I79_001275 | Uncharacterized protein. (119 aa) |
| | Map3k20 | Mitogen-activated protein kinase kinase kinase MLT. (445 aa) |
| | Rhno1 | Uncharacterized protein C12orf32-like. (245 aa) |
| | Ccnd2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa) |
| | Tigar | Putative fructose-2,6-bisphosphatase TIGAR. (266 aa) |
| | I79_001367 | RAD51-associated protein 1. (336 aa) |
| | I79_001484 | 65 kDa Yes-associated protein. (257 aa) |
| | Ercc8 | DNA excision repair protein ERCC-8. (397 aa) |
| | Brat1 | HEAT repeat-containing protein C7orf27. (822 aa) |
| | I79_002013 | BRCA1-A complex subunit BRE. (288 aa) |
| | I79_002347 | Fanconi anemia group D2 protein-like. (261 aa) |
| | Fancd2 | Fanconi anemia group D2 protein-like. (1068 aa) |
| | Rad54l | DNA repair and recombination protein RAD54-like. (306 aa) |
| | Topbp1 | DNA topoisomerase II-binding protein 1. (1517 aa) |
| | Tp53bp1 | Tumor suppressor p53-binding protein 1. (1952 aa) |
| | Uimc1 | BRCA1-A complex subunit RAP80. (722 aa) |
| | I79_004195 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (501 aa) |
| | Fam216a | Cell cycle checkpoint control protein RAD9B-like. (231 aa) |
| | I79_020102 | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | I79_020287 | X-ray radiation resistance-associated protein 1. (520 aa) |
| | Nox4 | NADPH oxidase 4. (130 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (237 aa) |
| | Lzic | Protein LZIC. (167 aa) |
| | Prap1 | Proline-rich acidic protein 1. (148 aa) |
| | Polg | DNA polymerase subunit gamma-1. (1215 aa) |
| | Nabp1 | SOSS complex subunit B2. (198 aa) |
| | Ticrr | Uncharacterized protein C15orf42-like. (1305 aa) |
| | Aen | Apoptosis-enhancing nuclease. (320 aa) |
| | I79_021404 | Putative DNA helicase INO80 complex-like 1. (1058 aa) |
| | Vcam1 | Vascular cell adhesion protein 1. (220 aa) |
| | Kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | Tmem109 | Transmembrane protein 109. (242 aa) |
| | Blm | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (464 aa) |
| | I79_023244 | Bloom syndrome protein-like. (721 aa) |
| | Xrcc6 | ATP-dependent DNA helicase 2 subunit 1. (608 aa) |
| | I79_024061 | Ubiquitin carboxyl-terminal hydrolase 28; Belongs to the peptidase C19 family. (1027 aa) |
| | I79_024097 | Vascular cell adhesion protein 1. (225 aa) |
| | I79_024437 | Enterin neuropeptides. (161 aa) |
| | I79_025001 | Lysine-specific demethylase 4D. (139 aa) |
| | Smpd1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (593 aa) |
| | I79_025438 | Uncharacterized protein C10orf90. (366 aa) |
| | I79_025641 | BRCA1-A complex subunit Abraxas. (82 aa) |
| | Myc | Myc proto-oncogene protein. (281 aa) |
| | Paxip1 | PAX-interacting protein 1. (91 aa) |
| | Cryab | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa) |
| | Mta1 | Metastasis-associated protein MTA1. (697 aa) |
| | Nek1 | Serine/threonine-protein kinase Nek1. (1232 aa) |
| | Mfsd11 | UNC93-like protein MFSD11. (446 aa) |
| | I79_004955 | Nuclear ubiquitous casein and cyclin-dependent kinases substrate. (173 aa) |
| | Xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | I79_005151 | BRCA1-A complex subunit MERIT40. (362 aa) |
| | I79_005573 | Secreted frizzled-related protein 2. (268 aa) |
| | Msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa) |
| | Wrn | Werner syndrome ATP-dependent helicase-like. (1405 aa) |
| | I79_005867 | Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa) |
| | Ect2 | Protein ECT2. (881 aa) |
| | I79_006232 | PAX-interacting protein 1. (79 aa) |
| | Gpx1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa) |
| | Itgb6 | Integrin beta; Belongs to the integrin beta chain family. (792 aa) |
| | Cav1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | Cop1 | E3 ubiquitin-protein ligase RFWD2. (556 aa) |
| | Sirt1 | NAD-dependent deacetylase sirtuin-1. (554 aa) |
| | Ints3 | Integrator complex subunit 3. (1041 aa) |
| | I79_007993 | Dual specificity protein kinase CLK2. (137 aa) |
| | Clk2 | Dual specificity protein kinase CLK2. (109 aa) |
| | Chek2 | Serine/threonine-protein kinase Chk2. (539 aa) |
| | Zmpste24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | Rhob | Rho-related GTP-binding protein RhoB. (196 aa) |
| | Bcl2l1 | Bcl-2-like protein 1. (233 aa) |
| | Pml | Putative transcription factor PML. (540 aa) |
| | Egr1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (421 aa) |
| | Stk11 | Serine/threonine-protein kinase 11. (505 aa) |
| | I79_009416 | Serine-protein kinase ATM. (1640 aa) |
| | Gtf2h5 | General transcription factor IIH subunit 5. (71 aa) |
| | Tlk2 | Serine/threonine-protein kinase tousled-like 2. (750 aa) |
| | Fignl1 | Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa) |
| | Fbxo4 | F-box only protein 4. (248 aa) |
| | Prkaa1 | Non-specific serine/threonine protein kinase. (477 aa) |
| | Polb | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | Sfrp1 | Secreted frizzled-related protein 1. (104 aa) |
| | Alad | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa) |
| | Kdm1a | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa) |
| | Nipbl | Nipped-B-like protein. (104 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | Rad1 | Cell cycle checkpoint protein RAD1. (279 aa) |
| | I79_011207 | DNA repair protein XRCC4. (176 aa) |
| | Trex1 | Three prime repair exonuclease 1. (320 aa) |
| | Brca1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa) |
| | I79_011834 | Breast cancer type 2 susceptibility protein-like. (143 aa) |
| | Brca2 | Breast cancer type 2 susceptibility protein-like. (3008 aa) |
| | I79_012384 | Leukocyte common antigen. (962 aa) |
| | I79_012568 | UPF0544 protein C5orf45-like. (154 aa) |
| | Mrnip | UPF0544 protein C5orf45-like. (195 aa) |
| | H671_21027 | DNA excision repair protein ERCC-1. (111 aa) |
| | Inip | SOSS complex subunit C-like protein. (104 aa) |
| | I79_012727 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa) |
| | I79_012829 | Histone H2A; Belongs to the histone H2A family. (146 aa) |
| | Tnks1bp1 | 182 kDa tankyrase-1-binding protein. (1693 aa) |
| | Nabp2 | SOSS complex subunit B1. (211 aa) |
| | Kdm4d | Lysine-specific demethylase 4D. (324 aa) |
| | I79_013864 | Lysine-specific demethylase 4D. (160 aa) |
| | Trim13 | Tripartite motif-containing protein 13. (407 aa) |
| | Ddias | Nitric oxide-inducible gene protein. (902 aa) |
| | Parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (971 aa) |
| | Bard1 | BRCA1-associated RING domain protein 1. (670 aa) |
| | Sod2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa) |
| | I79_015356 | Heat shock factor protein 1. (524 aa) |
| | Elk1 | ETS domain-containing protein Elk-1. (425 aa) |
| | Hus1 | Checkpoint protein; Belongs to the HUS1 family. (281 aa) |
| | Rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | Xrcc2 | DNA repair protein XRCC2. (222 aa) |
| | I79_016307 | Lys-63-specific deubiquitinase BRCC36-like. (291 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (349 aa) |
| | I79_016810 | Serine-protein kinase ATM. (473 aa) |
| | Rnf4 | RING finger protein 4. (128 aa) |
