STRINGSTRING
I79_009115 I79_009115 I79_009116 I79_009116 I79_009191 I79_009191 Itgb3 Itgb3 Map3k3 Map3k3 Vegfc Vegfc I79_009958 I79_009958 Thbs1 Thbs1 Gata2 Gata2 Smoc2 Smoc2 Grn Grn Pik3c2a Pik3c2a Jcad Jcad I79_012336 I79_012336 Fgf16 Fgf16 I79_012556 I79_012556 Atp5f1b Atp5f1b I79_013867 I79_013867 Nus1 Nus1 Ccbe1 Ccbe1 Sp1 Sp1 Plcg1 Plcg1 I79_015916 I79_015916 Akt3 Akt3 Hif1a Hif1a Nrp1 Nrp1 Dicer1 Dicer1 Fut2 Fut2 Lgmn Lgmn Pdgfb Pdgfb Kctd5 Kctd5 Bcar1 Bcar1 Emc10 Emc10 Anxa1 Anxa1 I79_018849 I79_018849 Pik3cd Pik3cd H671_5g14804 H671_5g14804 Tgfb1 Tgfb1 Hmox1 Hmox1 I79_020968 I79_020968 I79_020969 I79_020969 Lcn2 Lcn2 I79_021045 I79_021045 I79_021283 I79_021283 I79_021564 I79_021564 Hdac7 Hdac7 I79_022034 I79_022034 I79_022056 I79_022056 I79_022271 I79_022271 I79_022645 I79_022645 Rras Rras I79_023268 I79_023268 Itgb1bp1 Itgb1bp1 Cib1 Cib1 Gfus Gfus Fgfbp1 Fgfbp1 I79_025933 I79_025933 Rhob Rhob Gata3 Gata3 Prox1 Prox1 Wnt7a Wnt7a Foxp1 Foxp1 Plpp3 Plpp3 Wnt5a Wnt5a Plk2 Plk2 Rac1 Rac1 Map2k3 Map2k3 Rin2 Rin2 Ptgs2 Ptgs2 Agt Agt Alox12 Alox12 Bmpr2 Bmpr2 Pdcd6 Pdcd6 I79_003683 I79_003683 Adgra2 Adgra2 I79_004031 I79_004031 Nfe2l2 Nfe2l2 Akt1 Akt1 I79_004922 I79_004922 I79_005201 I79_005201 I79_005202 I79_005202 Rhoj Rhoj Sparc Sparc Srpx2 Srpx2 Igf1 Igf1 Angpt4 Angpt4 I79_006225 I79_006225 I79_006254 I79_006254 Sema5a Sema5a Ets1 Ets1 Cd40 Cd40 I79_007015 I79_007015 Bcas3 Bcas3 I79_007063 I79_007063 I79_007264 I79_007264 Sirt1 Sirt1 I79_007391 I79_007391 Atp5f1a Atp5f1a I79_007548 I79_007548 I79_007624 I79_007624 I79_007693 I79_007693 I79_008095 I79_008095 Calr Calr Hdac9 Hdac9 Gpld1 Gpld1 Zc3h12a Zc3h12a Fgf1 Fgf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_009115Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (441 aa)
I79_009116Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (311 aa)
I79_009191Basigin. (437 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
Map3k3Mitogen-activated protein kinase kinase kinase 3. (616 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
I79_009958Angiopoietin-1 receptor. (793 aa)
Thbs1Thrombospondin-1. (533 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Smoc2SPARC-related modular calcium-binding protein 2. (457 aa)
GrnGranulins. (592 aa)
Pik3c2aPhosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide; Belongs to the PI3/PI4-kinase family. (637 aa)
JcadUncharacterized protein KIAA1462. (954 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
I79_012556Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1227 aa)
Atp5f1bATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (534 aa)
I79_013867Angiomotin-like protein 1. (941 aa)
Nus1Nogo-B receptor. (193 aa)
Ccbe1Collagen and calcium-binding EGF domain-containing protein 1. (303 aa)
Sp1Transcription factor Sp1. (778 aa)
Plcg1Phosphoinositide phospholipase C. (1217 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Fut2L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (646 aa)
LgmnLegumain. (438 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Kctd53-phosphoinositide-dependent protein kinase 1; Belongs to the peptidase S1 family. (799 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1. (879 aa)
Emc10UPF0510 protein INM02. (222 aa)
Anxa1Annexin. (346 aa)
I79_018849Serine/threonine-protein kinase D2. (513 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (910 aa)
H671_5g14804Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1012 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
I79_020969Fibroblast growth factor 18. (85 aa)
Lcn2Neutrophil gelatinase-associated lipocalin; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
I79_021045Heme oxygenase 1. (81 aa)
I79_021283Angiopoietin-1. (298 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Hdac7Histone deacetylase 7. (424 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
I79_022056Annexin. (319 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
I79_022645Programmed cell death protein 6. (224 aa)
RrasRas-related protein R-Ras. (126 aa)
I79_023268Disintegrin and metalloproteinase domain-containing protein 17. (527 aa)
Itgb1bp1Integrin beta-1-binding protein 1. (199 aa)
Cib1Calcium and integrin-binding protein 1. (191 aa)
GfusGDP-L-fucose synthetase. (321 aa)
Fgfbp1Fibroblast growth factor-binding protein 1. (248 aa)
I79_025933Programmed cell death protein 6. (60 aa)
RhobRho-related GTP-binding protein RhoB. (196 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Prox1Prospero homeobox protein 1. (738 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (282 aa)
Foxp1Forkhead box protein P1. (696 aa)
Plpp3Lipid phosphate phosphohydrolase 3. (312 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Plk2Serine/threonine-protein kinase PLK. (682 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
Map2k3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (340 aa)
Rin2Ras and Rab interactor 2. (896 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Alox12Arachidonate 12-lipoxygenase, 12S-type. (553 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Pdcd6Programmed cell death protein 6. (83 aa)
I79_003683Nogo-B receptor. (291 aa)
Adgra2Putative G-protein coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1048 aa)
I79_004031Fibroblast growth factor receptor. (731 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
I79_004922SAM and SH3 domain-containing protein 1. (999 aa)
I79_005201Serine/threonine-protein kinase D1. (116 aa)
I79_005202Serine/threonine-protein kinase D1. (748 aa)
RhojRho-related GTP-binding protein RhoJ. (170 aa)
SparcSPARC. (249 aa)
Srpx2Sushi repeat-containing protein SRPX2. (283 aa)
Igf1Insulin-like growth factor I. (75 aa)
Angpt4Angiopoietin-4. (499 aa)
I79_006225Sonic hedgehog protein. (226 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Sema5aSemaphorin-5A. (1046 aa)
Ets1Protein C-ets-1. (257 aa)
Cd40Tumor necrosis factor receptor superfamily member 5. (118 aa)
I79_007015Breast carcinoma-amplified sequence 3-like. (717 aa)
Bcas3Breast carcinoma-amplified sequence 3. (92 aa)
I79_007063Hepatocyte growth factor receptor. (1222 aa)
I79_007264Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (84 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007391ATP synthase subunit alpha, mitochondrial. (65 aa)
Atp5f1aATP synthase subunit alpha, mitochondrial. (285 aa)
I79_007548Angiopoietin-1. (112 aa)
I79_007624Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1071 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
I79_008095Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (213 aa)
CalrCalreticulin. (417 aa)
Hdac9Histone deacetylase 9. (576 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
Zc3h12aRibonuclease ZC3H12A. (577 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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