STRINGSTRING
Pfkfb2 Pfkfb2 Ppp1r3b Ppp1r3b I79_003945 I79_003945 Sesn2 Sesn2 Ptafr Ptafr I79_004236 I79_004236 Akt1 Akt1 Enpp1 Enpp1 I79_020647 I79_020647 Sik1 Sik1 I79_020120 I79_020120 Rubcnl Rubcnl I79_019839 I79_019839 Bckdk Bckdk Igfbp4 Igfbp4 I79_010352 I79_010352 I79_010620 I79_010620 Ranbp2 Ranbp2 I79_010863 I79_010863 Pdk2 Pdk2 Ppp4r3b Ppp4r3b I79_004757 I79_004757 Myog Myog Adipor1 Adipor1 Ppp1r3c Ppp1r3c Rgn Rgn Nln Nln C1qtnf3 C1qtnf3 I79_011304 I79_011304 P2ry1 P2ry1 Slc4a1 Slc4a1 Kat2a Kat2a Stat3 Stat3 Gck Gck Ppp1r3f Ppp1r3f I79_012336 I79_012336 Akt2 Akt2 Cry1 Cry1 I79_012722 I79_012722 Pdk3 Pdk3 Ier3 Ier3 I79_013328 I79_013328 I79_013329 I79_013329 Git1 Git1 I79_013817 I79_013817 I79_014111 I79_014111 Pdk4 Pdk4 Epm2aip1 Epm2aip1 Inpp5k Inpp5k Foxa2 Foxa2 I79_015895 I79_015895 I79_015916 I79_015916 Dusp12 Dusp12 Gper1 Gper1 Dgat2 Dgat2 I79_015045 I79_015045 I79_015109 I79_015109 Gpt Gpt Insr Insr Ppargc1a Ppargc1a Ep300 Ep300 Actn3 Actn3 Hnf4a Hnf4a Pth Pth Foxo1 Foxo1 Hif1a Hif1a Hdac4 Hdac4 Adipoq Adipoq I79_015980 I79_015980 I79_018194 I79_018194 C1qtnf12 C1qtnf12 Ppp1ca Ppp1ca Ppp4r3a Ppp4r3a Serpina12 Serpina12 Erfe Erfe Nnmt Nnmt Ddit4 Ddit4 I79_005309 I79_005309 LHCGR LHCGR Nfe2l1 Nfe2l1 Igf1 Igf1 Pfkfb1 Pfkfb1 I79_006470 I79_006470 I79_006650 I79_006650 Mst1 Mst1 Sirt1 Sirt1 Pgp Pgp I79_007993 I79_007993 Clk2 Clk2 Irs2 Irs2 I79_024210 I79_024210 Phlda2 Phlda2 Tcf7l2 Tcf7l2 Ddb1 Ddb1 Zmpste24 Zmpste24 Gpld1 Gpld1 C1qtnf2 C1qtnf2 Dgkq Dgkq Lcmt1 Lcmt1 Znf692 Znf692 Rora Rora P2ry6 P2ry6 Ppara Ppara I79_022390 I79_022390 I79_022343 I79_022343 Mtor Mtor I79_020783 I79_020783 I79_009790 I79_009790 Ntsr1 Ntsr1 Plek Plek Nr3c1 Nr3c1 Stk11 Stk11 Midn Midn I79_009443 I79_009443 I79_009691 I79_009691 I79_021840 I79_021840 Fam3c Fam3c Irs1 Irs1 I79_021679 I79_021679 Wdr5 Wdr5 Scarb2 Scarb2 I79_025689 I79_025689 C1qtnf6 C1qtnf6 I79_024892 I79_024892 Arpp19 Arpp19 slc25B4 slc25B4 CgPICR_005189 CgPICR_005189 Cbfa2t3 Cbfa2t3 Mlycd Mlycd Slc25a12 Slc25a12 Pdk1 Pdk1 Tigar Tigar Gnb3 Gnb3 I79_001592 I79_001592 Prkce Prkce Plcd1 Plcd1 Ncor1 Ncor1 I79_001744 I79_001744 Usp7 Usp7 Acadm Acadm I79_001927 I79_001927 Ppp1r3a Ppp1r3a Ppp1cb Ppp1cb I79_002020 I79_002020 Gcgr Gcgr I79_002406 I79_002406 Foxk2 Foxk2 I79_002536 I79_002536 I79_002566 I79_002566 Soga1 Soga1 Src Src Dyrk2 Dyrk2 Lep Lep
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pfkfb26-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2. (784 aa)
Ppp1r3bProtein phosphatase 1 regulatory subunit. (284 aa)
I79_003945Cytochrome c oxidase assembly protein COX11, mitochondrial. (142 aa)
Sesn2Sestrin-2. (480 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
I79_004236Protein-serine/threonine kinase. (49 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020647Protein FAM48A. (330 aa)
Sik1Serine/threonine-protein kinase SIK1. (729 aa)
I79_020120Uncharacterized protein C13orf18-like. (318 aa)
RubcnlUncharacterized protein C13orf18-like. (339 aa)
I79_019839Nuclear receptor coactivator. (1413 aa)
BckdkProtein-serine/threonine kinase. (412 aa)
Igfbp4Insulin-like growth factor-binding protein 4. (254 aa)
I79_010352Acetyl-CoA carboxylase 2. (2287 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Ranbp2E3 SUMO-protein ligase RanBP2. (3068 aa)
I79_010863Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (533 aa)
Pdk2Protein-serine/threonine kinase. (407 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B. (1364 aa)
I79_004757Complement C1q tumor necrosis factor-related protein 1. (314 aa)
MyogMyogenin. (224 aa)
Adipor1Adiponectin receptor protein 1. (375 aa)
Ppp1r3cProtein phosphatase 1 regulatory subunit. (312 aa)
RgnRegucalcin. (265 aa)
NlnNeurolysin, mitochondrial. (704 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
I79_011304Parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (626 aa)
P2ry1p2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Slc4a1Anion exchange protein. (915 aa)
Kat2aHistone acetyltransferase KAT2A. (663 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
GckPhosphotransferase. (465 aa)
Ppp1r3fProtein phosphatase 1 regulatory subunit 3F. (477 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Cry1Cryptochrome-1. (428 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
Pdk3Protein-serine/threonine kinase. (415 aa)
Ier3Radiation-inducible immediate-early gene IEX-1. (160 aa)
I79_013328Glycine N-methyltransferase. (71 aa)
I79_013329Glycine N-methyltransferase. (69 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
I79_014111Protein-serine/threonine kinase. (60 aa)
Pdk4Protein-serine/threonine kinase. (178 aa)
Epm2aip1EPM2A-interacting protein 1. (606 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (451 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
I79_015895Sorbin and SH3 domain-containing protein 1. (852 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Dusp12Dual specificity protein phosphatase 12. (291 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
I79_015045MAS proto-oncogene. (172 aa)
I79_015109Interleukin-6. (174 aa)
GptAlanine aminotransferase 1. (481 aa)
InsrInsulin receptor. (114 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Ep300Histone acetyltransferase p300. (2415 aa)
Actn3Alpha-actinin-3. (900 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Foxo1Forkhead box protein O1. (469 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
AdipoqAdiponectin. (248 aa)
I79_015980Leptin receptor. (533 aa)
I79_018194Protein FAM132A. (127 aa)
C1qtnf12Protein FAM132A. (61 aa)
Ppp1caSerine/threonine-protein phosphatase PP1-alpha catalytic subunit. (148 aa)
Ppp4r3aSerine/threonine-protein phosphatase 4 regulatory subunit 3A. (400 aa)
Serpina12Serpin A12; Belongs to the serpin family. (414 aa)
ErfeProtein FAM132B. (344 aa)
NnmtNicotinamide N-methyltransferase. (265 aa)
Ddit4DNA-damage-inducible transcript 4 protein. (231 aa)
I79_005309PAS domain-containing serine/threonine-protein kinase. (1162 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
Nfe2l1Nuclear factor erythroid 2-related factor 1. (740 aa)
Igf1Insulin-like growth factor I. (75 aa)
Pfkfb16-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1-like isoform 1. (448 aa)
I79_006470Natural killer cell receptor 2B4. (280 aa)
I79_006650Hepatocyte growth factor-like protein. (93 aa)
Mst1Hepatocyte growth factor-like protein. (88 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
PgpPhosphoglycolate phosphatase. (617 aa)
I79_007993Dual specificity protein kinase CLK2. (137 aa)
Clk2Dual specificity protein kinase CLK2. (109 aa)
Irs2Insulin receptor substrate 2. (465 aa)
I79_024210Nuclear protein 1. (103 aa)
Phlda2Pleckstrin-likey-like domain family A member 2. (134 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
DgkqDiacylglycerol kinase. (491 aa)
Lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (328 aa)
Znf692Zinc finger protein 692. (222 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
P2ry6p2Y purinoceptor 6. (328 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_009790MAS proto-oncogene; Belongs to the G-protein coupled receptor 1 family. (324 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PlekPleckstrin. (327 aa)
Nr3c1Glucocorticoid receptor. (748 aa)
Stk11Serine/threonine-protein kinase 11. (505 aa)
MidnMidnolin. (317 aa)
I79_009443Steroid hormone receptor ERR2. (475 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
I79_021840Nuclear receptor ROR-gamma. (341 aa)
Fam3cProtein FAM3C. (227 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_021679POU domain protein. (218 aa)
Wdr5WD repeat-containing protein 5. (334 aa)
Scarb2Lysosome membrane protein 2; Belongs to the CD36 family. (438 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
C1qtnf6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
I79_024892Fructose-1,6-bisphosphatase 1. (66 aa)
Arpp19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
slc25B4UDP-xylose and UDP-N-acetylglucosamine transporter. (331 aa)
CgPICR_005189cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (96 aa)
Cbfa2t3Protein CBFA2T3. (593 aa)
MlycdMalonyl-CoA decarboxylase, mitochondrial. (190 aa)
Slc25a12Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (646 aa)
Pdk1Protein-serine/threonine kinase. (344 aa)
TigarPutative fructose-2,6-bisphosphatase TIGAR. (266 aa)
Gnb3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (227 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
PrkceProtein kinase C epsilon type. (137 aa)
Plcd1Phosphoinositide phospholipase C. (782 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7. (82 aa)
AcadmMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (96 aa)
I79_001927Protein phosphatase 1 regulatory subunit 3A. (263 aa)
Ppp1r3aProtein phosphatase 1 regulatory subunit 3A. (692 aa)
Ppp1cbSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (299 aa)
I79_002020Glucokinase regulatory protein. (583 aa)
GcgrGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (486 aa)
I79_002406NAD-dependent deacetylase sirtuin-7. (306 aa)
Foxk2Forkhead box protein K2. (448 aa)
I79_002536Pro-opiomelanocortin. (159 aa)
I79_002566Ketohexokinase. (345 aa)
Soga1Uncharacterized protein C20orf117. (1897 aa)
SrcTyrosine-protein kinase. (536 aa)
Dyrk2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (528 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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