STRINGSTRING
Prkca Prkca I79_009691 I79_009691 I79_013817 I79_013817 Inpp5k Inpp5k Tnf Tnf I79_016547 I79_016547 Ostn Ostn Prkcb Prkcb Enpp1 Enpp1 Pid1 Pid1 Ahi1 Ahi1 Myc Myc Gsk3a Gsk3a IL1B IL1B I79_017273 I79_017273 Stxbp3 Stxbp3 Fabp5 Fabp5 Lep Lep Pea15 Pea15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (451 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
OstnOsteocrin. (105 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
Ahi1Jouberin. (988 aa)
MycMyc proto-oncogene protein. (281 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
I79_017273Protein kinase C alpha type. (128 aa)
Stxbp3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
Fabp5Fatty acid-binding protein, epidermal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Pea15Astrocytic phosphoprotein PEA-15. (130 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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